anti-PTK2B (PTK2B) 抗体产品概述

Full name:
anti-PTK2B Protein tyrosine Kinase 2 beta 抗体 (PTK2B)
在www.antibodies-online.cn可供257 PTK2B Protein tyrosine Kinase 2 beta (PTK2B) 抗体的25不同的供货商。 再加上,我们可以发PTK2B 试剂盒 (23)PTK2B 蛋白 (14)和数多这个蛋白质的别的产品。 总共312 PTK2B产品已列进来了。
别名:
Akt, CADTK, CAKB, CAKbeta, E430023O05Rik, FADK2, FAK2, PKB, PKB/Akt, PKBalpha, PTK, Pyk2, Rac, Raftk

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引用最多的anti-PTK2B 抗体

  1. Human Polyclonal PTK2B Primary Antibody for IF, IHC (p) - ABIN196952 : Gluck: Acid sensing in renal epithelial cells. in The Journal of clinical investigation 2004 (PubMed)
    Show all 5 references for 196952

  2. Human Monoclonal PTK2B Primary Antibody for IHC, ELISA - ABIN1724705 : Dylla, Deyle, Theunissen, Padurean, Verfaillie: Integrin engagement-induced inhibition of human myelopoiesis is mediated by proline-rich tyrosine kinase 2 gene products. in Experimental hematology 2004 (PubMed)
    Show all 3 references for 1724705

  3. Human Polyclonal PTK2B Primary Antibody for ELISA, WB - ABIN1533144 : Lev, Moreno, Martinez, Canoll, Peles, Musacchio, Plowman, Rudy, Schlessinger: Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions. in Nature 1995 (PubMed)
    Show all 2 references for 1533144

  4. Human Polyclonal PTK2B Primary Antibody for IHC, ELISA - ABIN1532112 : Herzog, Nicholl, Hort, Sutherland, Shine: Molecular cloning and assignment of FAK2, a novel human focal adhesion kinase, to 8p11.2-p22 by nonisotopic in situ hybridization. in Genomics 1997 (PubMed)
    Show all 2 references for 1532112

  5. Human Polyclonal PTK2B Primary Antibody for IF, IHC (p) - ABIN197440 : Benzing, Gerke, Höpker, Hildebrandt, Kim, Walz: Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2. in Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
    Show all 2 references for 197440

  6. Human Polyclonal PTK2B Primary Antibody for IF (p), IHC (p) - ABIN745763 : Cao, Zheng, Wang, Wang, Li, Li, Lai, Wang, Qin: Src blockage by siRNA inhibits VEGF-induced vascular hyperpemeability and osteoclast activity - an in vitro mechanism study for preventing destructive repair of osteonecrosis. in Bone 2015 (PubMed)

  7. Cow (Bovine) Polyclonal PTK2B Primary Antibody for WB - ABIN2779800 : Ling, Sheng, Braun: The calcium-dependent activity of large-conductance, calcium-activated K+ channels is enhanced by Pyk2- and Hck-induced tyrosine phosphorylation. in American journal of physiology. Cell physiology 2004 (PubMed)

  8. Human Polyclonal PTK2B Primary Antibody for ICC, IF - ABIN257536 : Lu, Chen, Shimoda, Park, Zhang, Tran, Zhang, Semenza: Chemotherapy-Induced Ca(2+) Release Stimulates Breast Cancer Stem Cell Enrichment. in Cell reports 2017 (PubMed)

更多抗PTK2B的相互作用对抗体

Mouse (Murine) PTK2B Protein tyrosine Kinase 2 beta (PTK2B) interaction partners

  1. TSC1 (显示 TSC1 抗体)/TSC2 (显示 TSC2 抗体) complex upregulation of OPN (显示 SPP1 抗体) expression is mediated by transcription factor SOX9 (显示 SOX9 抗体) in an mTOR (显示 FRAP1 抗体)-independent manner. Moreover, ablation of OPN (显示 SPP1 抗体) by deficient TSC1 (显示 TSC1 抗体)/TSC2 (显示 TSC2 抗体) complex contributed to inactivation of AKT (显示 AKT1 抗体) in TSC (显示 SLC12A3 抗体) cells

  2. Our results suggest that increasing Akt (显示 AKT1 抗体)/ NF-kappaB (显示 NFKB1 抗体) is a crucial mediator of skin aging, which can increase the susceptibility of cell transformation.

  3. findings highlight a pivotal link between an epigenetic regulator, WHSC1, and key intracellular signaling molecules, AKT, RICTOR, and Rac1, to drive prostate cancer metastasis.

  4. Studies indicate that the Pten (显示 PTEN 抗体)+/- genotype displayed neoplasia in multiple organs, including the endometrium and that the Pten (显示 PTEN 抗体) is a key regulatory player in the PI3K/PTEN (显示 PTEN 抗体)/AKT (显示 AKT1 抗体) pathway.

  5. a simple, linear, four-compartment ordinary differential equation (ODE) model of Akt (显示 AKT1 抗体) activation that tracks both the biochemical state and the physical location of Akt (显示 AKT1 抗体), is reported.

  6. Psgl-1 (显示 SELPLG 抗体) deficiency accelerates bleomycin-induced lung fibrosis and inflammation in mice through activating the PI3K/AKT (显示 AKT1 抗体) axis.

  7. Data show that docetaxel, rapamycin and tanespimycin multi-drug loaded micelles targeted against HSP90 (显示 HSP90 抗体) and the PI3K/AKT (显示 AKT1 抗体)/mTOR (显示 FRAP1 抗体) pathway in prostate cancer.

  8. results show that Pyk2 contributes to cytotoxic T lymphocyte(CTL) migration by regulating detachment of CTL at the trailing edge, which could explain why Pyk2 is important for chemotactic and migratory responses.

  9. Furthermore, Leishmania RNA virus 1-induced TLR-3 (显示 TLR3 抗体) activation promoted parasite persistence by enhancing macrophage survival through Akt (显示 AKT1 抗体) activation in a manner partially dependent on miR (显示 MLXIP 抗体)-155.

  10. Collectively, these findings showed that SA suppressed mammary gland development of pubertal mice, which was coincident with the SA-inhibited HC11 (显示 CCL2 抗体) proliferation, and was associated with inhibition of PI3K/Akt (显示 AKT1 抗体) signaling pathway through activation of GPR120 (显示 O3FAR1 抗体).

Human PTK2B Protein tyrosine Kinase 2 beta (PTK2B) interaction partners

  1. Our findings suggest that Pyk2 plays an important role in the coordination of stabilization of beta-catenin (显示 CTNNB1 抗体) in the crosstalk between Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) and Wnt (显示 WNT2 抗体)/Ca(2 (显示 CA2 抗体)+) signaling pathways upon Wnt3a (显示 WNT3A 抗体) stimulation in differentiating hNPCs.

  2. STIM1 (显示 STIM1 抗体)-induced Ca(2 (显示 CA2 抗体)+) signaling activates Pyk2 to inhibit the interaction of VE-PTP (显示 PTPRB 抗体) and VE-cadherin (显示 CDH5 抗体) and hence increase endothelial permeability.

  3. Ascites and CCL18 (显示 CCL18 抗体) stimulate the phosphorylation and expression of Pyk2, which positively regulates ascites-induced ovarian cancer cell migration.

  4. We demonstrated trophoblast cytoprotection by intervention with supraphysiological concentrations of relaxin, a process in part mediated through the PI3-kinase (显示 PIK3CA 抗体)-Akt/PKB (显示 AKT1 抗体) cell survival pathway. These results provide further rationale for clinical investigation of relaxin as a potential therapeutic in preeclampsia.

  5. PTK2B polymorphism (rs28834970) could modify the risk of late-onset Alzheimer's disease (LOAD), and PTK2B polymorphism (rs28834970) and APOE may interact to increase LOAD risk in a Han Chinese population.

  6. Studies suggest that PYK2 is a common downstream effector of ErbB (显示 EGFR 抗体) and IL8 (显示 IL8 抗体) receptors, and that PYK2 integrates their signaling pathways through a positive feedback loop to potentiate breast cancer invasion.

  7. Pyk2 is a key downstream signaling molecules of CCR7 (显示 CCR7 抗体) in SCCHN, which promotes SCCHN tumorigenesis and progression.

  8. Phosphoproteomic analysis identifies FAK2 as a potential therapeutic target for tamoxifen resistance in breast cancer.

  9. Pyk2-focal adhesion targeting domain interacts with and binds to leupaxin (显示 LPXN 抗体).

  10. Src (显示 SRC 抗体) has a role in priming Pyk2 (but not FAK (显示 PTK2 抗体)) phosphorylation and subsequent activation downstream of integrins

Cow (Bovine) PTK2B Protein tyrosine Kinase 2 beta (PTK2B) interaction partners

  1. Ptk2b activation may play a key role in the signaling responses in ECs under hemodynamic influence [proline-rich tyrosine kinase 2]

PTK2B 抗原简介

Antigen Summary

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with PTK2B

  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) 抗体
  • thymoma viral proto-oncogene 1 (Akt1) 抗体
  • protein tyrosine kinase 2 beta (PTK2B) 抗体
  • protein tyrosine kinase 2 beta (Ptk2b) 抗体
  • PTK2 protein tyrosine kinase 2 beta (Ptk2b) 抗体
  • PTK2B protein tyrosine kinase 2 beta (PTK2B) 抗体
  • Akt 抗体
  • CADTK 抗体
  • CAKB 抗体
  • CAKbeta 抗体
  • E430023O05Rik 抗体
  • FADK2 抗体
  • FAK2 抗体
  • PKB 抗体
  • PKB/Akt 抗体
  • PKBalpha 抗体
  • PTK 抗体
  • Pyk2 抗体
  • Rac 抗体
  • Raftk 抗体

Protein level used designations for PTK2B

AKT1 kinase , PKB alpha , RAC protein kinase alpha RAC-PK alpha , RAC-PK-alpha , RAC-alpha serine/threonine-protein kinase , murine thymoma viral (v-akt) oncogene homolog 1 , protein kinase B alpha , thymoma viral proto-oncogene 1 , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , CAK-beta , FADK 2 , PTK2B protein tyrosine kinase 2 beta , calcium-dependent tyrosine kinase , calcium-regulated non-receptor proline-rich tyrosine kinase , cell adhesion kinase beta , focal adhesion kinase 2 , proline-rich tyrosine kinase 2 , protein kinase B , protein-tyrosine kinase 2-beta , related adhesion focal tyrosine kinase , CADTK , CAK beta , PTK2 protein tyrosine kinase 2 beta , cellular adhesion kinase beta , protein tyrosine kinase 2 beta

GENE ID SPECIES
24185 Rattus norvegicus
11651 Mus musculus
2185 Homo sapiens
50646 Rattus norvegicus
19229 Mus musculus
486102 Canis lupus familiaris
541008 Bos taurus
421998 Gallus gallus
100157507 Sus scrofa
100342358 Oryctolagus cuniculus
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