CAMK4 蛋白 (CAMK4)产品概述

Full name:
Calcium/calmodulin-Dependent Protein Kinase IV 蛋白 (CAMK4)
在www.antibodies-online.cn可供17 Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) 蛋白的9不同的供货商。 再加上,我们可以发CAMK4 抗体 (179)CAMK4 试剂盒 (5)和数多这个蛋白质的别的产品。 总共216 CAMK4产品已列进来了。
别名:
A430110E23Rik, AI666733, caMK, CaMK-GR, CAMK4, camk4-A, CaMK IV, CaMKIV, CaMKIV/Gr, Ccdpk, D18Bwg0362e, IV, RATCCDPK, wu:fj42a03, zgc:110275
列出全部蛋白 基因 基因ID UniProt
CAMK4 814 Q16566
CAMK4 12326  
CAMK4 25050 P13234

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引用最多的CAMK4 蛋白

  1. Human CAMK4 Protein expressed in Baculovirus infected Insect Cells - ABIN2003189 : Chatila, Anderson, Ho, Means: A unique phosphorylation-dependent mechanism for the activation of Ca2+/calmodulin-dependent protein kinase type IV/GR. in The Journal of biological chemistry 1996 (PubMed)
    Show all 5 references for 2003189

  2. Mouse (Murine) CAMK4 Protein expressed in Baculovirus infected Insect Cells - ABIN2008360 : Melander Gradin, Marklund, Larsson, Chatila, Gullberg: Regulation of microtubule dynamics by Ca2+/calmodulin-dependent kinase IV/Gr-dependent phosphorylation of oncoprotein 18. in Molecular and cellular biology 1997 (PubMed)
    Show all 5 references for 2008360

  3. Human CAMK4 Protein expressed in Baculovirus infected Insect Cells - ABIN411947 : Wei, Qiu, Liauw, Robinson, Ho, Chatila, Zhuo: Calcium calmodulin-dependent protein kinase IV is required for fear memory. in Nature neuroscience 2002 (PubMed)
    Show all 4 references for 411947

  4. Human CAMK4 Protein expressed in Escherichia coli (E. coli) - ABIN668012 : Tombes, Grant, Westin, Krystal: G1 cell cycle arrest and apoptosis are induced in NIH 3T3 cells by KN-93, an inhibitor of CaMK-II (the multifunctional Ca2+/CaM kinase). in Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996 (PubMed)

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Human Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) interaction partners

  1. Within the pH range 5.0-11.5, CAMK4 maintained both its secondary and tertiary structures, along with its function, whereas significant aggregation was observed at acidic pH (2.0-4.5).

  2. A positive association was not observed between rs10491334 in the CAMK4 gene and longevity in a Chinese population.

  3. The T-allele of rs10491334 in CAMK4 was associated with hypertension in the Uygur group.

  4. Expression of CaMKIV inhibits autophosphorylation and activation of CaMKII (显示 CAMK2G 蛋白), and elicits G0/G1cell cycle arrest,impairing cell proliferation.

  5. An imbalance of specific isoforms of CYFIP1 (显示 CYFIP1 蛋白), an FMRP (显示 FMR1 蛋白) interaction partner, and CAMK4, a transcriptional regulator of the FMRP (显示 FMR1 蛋白) gene, modulates risk for autism spectrum disorders.

  6. CaMK4-dependent activation of AKT (显示 AKT1 蛋白)/mTOR (显示 FRAP1 蛋白) and CREM (显示 CREM 蛋白)-alpha underlies autoimmunity-associated Th17 imbalance.

  7. CaMK4 regulates beta-cell proliferation and apoptosis in a CREB (显示 CREB1 蛋白)-dependent manner and CaMK4-induced IRS-2 (显示 IRS2 蛋白) expression is important in these processes

  8. study suggests that the mutations in CAMK4 may lead to abnormal semen parameters

  9. Phosphorylated Notch1 (显示 NOTCH1 蛋白)-IC by CaMKIV increases Notch1 (显示 NOTCH1 蛋白)-IC stability, which enhances osteoclast differentiation.

  10. Prolongevity genes are activated by CAMKIV, the levels of which are influenced by rs10491334, a single-nucleotide polymorphism associated with human longevity.

Mouse (Murine) Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) interaction partners

  1. results imply that CaMKIV plays a role in maintenance the structure of chromatoid body by regulating the associations of proteins in it

  2. CaMK4 activity is increased in T cells from systemic lupus erythematosus mice compared with the control group.

  3. Results demonstrated that genetically inhibiting the CaMKK (显示 CAMKK2 蛋白) pathway via CaMKKbeta or CaMK IV is detrimental in the response of female mice to cerebral ischemia

  4. CaMKIV-mTOR (显示 FRAP1 蛋白)-dependent autophagy is conserved in both immune and nonimmune/parenchymal cells and is fundamental for the respective functional and adaptive responses to septic insult.

  5. CaMK4-dependent activation of AKT (显示 AKT1 蛋白)/mTOR (显示 FRAP1 蛋白) and CREM (显示 CREM 蛋白)-alpha underlies autoimmunity-associated Th17 imbalance.

  6. The stimulation of CaMKII (显示 CAMK2G 蛋白) activity in the hippocampus is essential for rivastigmine-induced memory improvement in olfactory bulbectomized mice.

  7. CaMKK (显示 CAMKK2 蛋白)/CaMK IV pathway is a key endogenous protective mechanism in cerebral ischemia.

  8. CaMKIV has opposing roles in nicotine and cocaine reward.

  9. CaMK4 regulates beta-cell proliferation and apoptosis in a CREB (显示 CREB1 蛋白)-dependent manner and CaMK4-induced IRS-2 (显示 IRS2 蛋白) expression is important in these processes

  10. The reduced fertility of Crybb2 (显示 CRYbB2 蛋白) knockout male mice may result from the disordered proliferation and apoptosis of germ cells in the testis, possibly due to reduced CaMKIV from the loss of Crybb2 (显示 CRYbB2 蛋白).

Zebrafish Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) interaction partners

  1. We identified the zebrafish homologue of CaMKIV (zCaMKIV) on the basis of biochemical characterization. zCaMKIV showed similar biochemical properties as well as tissue and subcellular distributions to rat CaMKIV (rCaMKIV)

Pig (Porcine) Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) interaction partners

  1. Data suggest that Tyr (显示 TYR 蛋白)(99) phosphorylated calmodulin (显示 CALM 蛋白), as compared to non-phosphorylated, binds with a higher affinity at the calmodulin (显示 CALM 蛋白) binding site (rich in basic amino acids) of CaM kinase IV leading to increased activation of CaM kinase IV.

  2. conclude that the hypoxia-induced increased activation of CaM kinase IV cascade increases with the increase in the degree of cerebral tissue hypoxia as measured by cerebral tissue high energy phosphates in a curvilinear manner

蛋白简介CAMK4

蛋白简介

The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.

Alternative names and synonyms associated with CAMK4

  • calcium/calmodulin-dependent protein kinase IV-like (CAMK4L)
  • calcium/calmodulin-dependent protein kinase IV (CAMK4)
  • calcium/calmodulin-dependent protein kinase IV (camk4)
  • calcium/calmodulin-dependent protein kinase IV (Camk4)
  • A430110E23Rik 蛋白
  • AI666733 蛋白
  • caMK 蛋白
  • CaMK-GR 蛋白
  • CAMK4 蛋白
  • camk4-A 蛋白
  • CaMK IV 蛋白
  • CaMKIV 蛋白
  • CaMKIV/Gr 蛋白
  • Ccdpk 蛋白
  • D18Bwg0362e 蛋白
  • IV 蛋白
  • RATCCDPK 蛋白
  • wu:fj42a03 蛋白
  • zgc:110275 蛋白

Protein level used designations for CAMK4

calcium/calmodulin-dependent protein kinase type IV-like , calcium/calmodulin-dependent protein kinase IV , CAM kinase IV , CAM kinase- GR , brain Ca(2+)-calmodulin-dependent protein kinase type IV , brain Ca++-calmodulin-dependent protein kinase type IV , caM kinase-GR , calcium/calmodulin-dependent protein kinase type IV , calcium/calmodulin-dependent protein kinase type IV catalytic chain , CAM kinase-GR , Ca2+/calmodulin-dependent protein kinase type IV/Gr , caMK IV , Calmodulin-dependent protein kinase IV , calspermin , zCaMKIV

GENE ID SPECIES
427267 Gallus gallus
712322 Macaca mulatta
100388410 Callithrix jacchus
100461605 Pongo abelii
100473015 Ailuropoda melanoleuca
100583900 Nomascus leucogenys
373837 Xenopus laevis
814 Homo sapiens
100684140 Canis lupus familiaris
12326 Mus musculus
25050 Rattus norvegicus
550270 Danio rerio
723973 Gallus gallus
461992 Pan troglodytes
100337083 Bos taurus
100515364 Sus scrofa
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