Orthodenticle Homeobox 2 (OTX2) ELISA试剂盒产品概述

在www.antibodies-online.cn可供8 Orthodenticle Homeobox 2 (OTX2) ELISA试剂盒的6不同的供货商。 再加上,我们可以发Orthodenticle Homeobox 2 抗体 (105)Orthodenticle Homeobox 2 蛋白 (11)和数多这个蛋白质的别的产品。 总共129 Orthodenticle Homeobox 2产品已列进来了。
别名:
CPHD6, E130306E05Rik, id:ibd2915, MCOPS5, otx-2, otx2, Xotx-2, Xotx2, zgc:136535, zotx-2, zOtx2
list all ELISA KIts 基因 基因ID UniProt
OTX2 5015 P32243
OTX2 305858  
OTX2 18424  

Orthodenticle Homeobox 2 (OTX2) ELISA试剂盒 by Reactivity

适于 Orthodenticle Homeobox 2 相互作用对的更多 ELISA 试剂盒

Human Orthodenticle Homeobox 2 (OTX2) interaction partners

  1. One subgroup of atypical teratoid rhabdoid tumors was characterized by high expression of OTX2.

  2. TNF-alpha (显示 TNF ELISA试剂盒), secreted from activated Monocytes, mediates the downregulation of OTX2 and essential retinal pigment epithelium genes.

  3. OTX1 and OTX2 genes might have a role in the pathogenesis of different types of sinonasal neoplasms.

  4. OTX2 gene frameshift mutation is associated with microphthalmia, ectopic pituitary and growth hormone (显示 GH1 PLURAL_@44952@) deficiency.

  5. OTX2 mutations can cause ACTH (显示 POMC ELISA试剂盒) deficiency in the neonatal period. Study also shows that OTX2 mutations are associated with agenesis of the Left Internal Carotid Artery.

  6. A novel pathogenic variant in OTX2, c.651delC, p.(Thr218Hisfs*76) identified in a patient with syndromic bilateral anophthalmia .

  7. demonstrated the role of OTX2 on TAp63 regulation necessary for the correct formation of macular neuroepithelium

  8. Loss of OTX2 expression resulted in decreased expression of C-MYC (显示 MYC ELISA试剂盒) and CRX (显示 CRX ELISA试剂盒), genes previously implicated in retinoblastoma tumorigenesis. Loss of OTX2 expression increased the phosphorylation of RB, a potential mechanism of modulating cell proliferation

  9. A novel role for OTX2 in self-renewal and migration of human embryonic neural precursors and Medulloblastoma cells, is reported.

  10. We showed that miR (显示 MLXIP ELISA试剂盒)-410 directly regulates predicted target genes OTX2 and RPE65 (显示 RPE65 ELISA试剂盒).

Xenopus laevis Orthodenticle Homeobox 2 (OTX2) interaction partners

  1. barH-like homeobox-2 (显示 BARHL2 ELISA试剂盒) gene barhl2 (显示 BARHL2 ELISA试剂盒) acts downstream of orthodentricle-2 and together with iroquois-3 in establishment of the caudal (显示 CAD ELISA试剂盒) forebrain signaling center induced by Sonic Hedgehog (显示 SHH ELISA试剂盒)

  2. While otx2 and otx5 are both capable to promote cement gland formation, otx1 is not.

  3. direct interaction and interdependence between the Otx2 and Sox2 (显示 SOX2 ELISA试剂盒) proteins coordinate Rax (显示 RAX ELISA试剂盒) expression in eye development, providing molecular linkages among the genes responsible for ocular malformation.

Zebrafish Orthodenticle Homeobox 2 (OTX2) interaction partners

  1. Lbh-like is a new regulator of photoreceptor differentiation directly through modulating otx2 expression in zebrafish.

  2. These findings suggest that one or more Otx targets in addition to mitfa (显示 MITF ELISA试剂盒) and mitfb (显示 MITF ELISA试剂盒), possibly another mitf (显示 MITF ELISA试剂盒) family member, are necessary for development of the retinal pigmented epithelium in zebrafish.

  3. In vertebrates, the Otx2 promoter acquires multiple, spatiotemporally specific cis (显示 CISH ELISA试剂盒)-regulators in order to precisely control highly coordinated processes in head development.

  4. The Zona limitans intrathalamica is induced within the competence area established by Otx1l/2, and is posteriorly restricted by Irx1b.

Mouse (Murine) Orthodenticle Homeobox 2 (OTX2) interaction partners

  1. These results suggest that tau haploinsufficiency, without the compensation effect of MAP1A (显示 MAP1A ELISA试剂盒), induces reduction of Otx2 expression, increases prenatal cell death, and accordingly leads to selective loss of VTA DA neurons in the early postnatal stage.

  2. Otx2-mediated Nanog (显示 NANOG ELISA试剂盒) regulation contributes to the integrity of the embryonic stem cell state and cell lineage specification in preimplantation development (显示 MTA2 ELISA试剂盒).

  3. Our genetic model reveals that non-cell autonomous Otx2 regulates plasticity broadly across cortical modalities. In Otx2+/AAmice, PV+ cell maturation was delayed throughout the neocortex and ectopic windows of cortical plasticity arose in occipital, parietal and frontal areas, including A1 and mPFC.

  4. Postnatal secretion of this single-chain antibody by PV cells delays PV maturation and reduces plasticity gene expression. Induced adult expression of this single-chain antibody in cerebrospinal fluid decreases Otx2 internalization by PV cells, strongly induces plasticity gene expression and reopens physiological plasticity.

  5. bipolar cell subpopulation imports Otx2 protein from photoreceptors to protect itself from glutamate (显示 GRIN1 ELISA试剂盒) excitotoxicity in the dark.

  6. The Hmga2 gene is activated by Otx2 and Hmga2 protein binds to the enhancers targeted by Otx2, thus facilitating the engagement and/or the stable association of Otx2.

  7. the Otx2 interactome in the adult neural retina

  8. Otx2S is a novel variant of the Otx2 gene with a deletion within the homeodomain sequence. Otx2S is expressed in both the neural retina and retinal pigmented epithelium, and encodes a protein that is targeted to the nucleus.

  9. Otx2 critically depends on Lmx1b (显示 LMX1B ELISA试剂盒) for the formation of mdDA neurons.

  10. Otx2 was required for ventral, but not dorsal, identity, thus controlling the production of specific MGE derivatives.

Orthodenticle Homeobox 2 (OTX2) 抗原简介

Antigen Summary

This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.

Alternative names and synonyms associated with Orthodenticle Homeobox 2 (OTX2)

  • orthodenticle homeobox 2 (OTX2) Elisa Kit
  • orthodenticle homeobox 2 (Otx2) Elisa Kit
  • orthodenticle homeobox 2 (otx2-a) Elisa Kit
  • orthodenticle homolog 2 (otx2) Elisa Kit
  • orthodenticle homolog 2 (Drosophila) (Otx2) Elisa Kit
  • CPHD6 Elisa Kit
  • E130306E05Rik Elisa Kit
  • id:ibd2915 Elisa Kit
  • MCOPS5 Elisa Kit
  • otx-2 Elisa Kit
  • otx2 Elisa Kit
  • Xotx-2 Elisa Kit
  • Xotx2 Elisa Kit
  • zgc:136535 Elisa Kit
  • zotx-2 Elisa Kit
  • zOtx2 Elisa Kit

Protein level used designations for OTX2

homeobox protein OTX2 , orthodenticle homolog 2 , orthodenticle homeobox protein 2 , homeobox Otx2 , homeobox protein OTX2-A , orthodenticle 2-A , orthodenticle-A-like protein A , xOTX2-A , etID309955.17

GENE ID SPECIES
5015 Homo sapiens
395191 Gallus gallus
490708 Canis lupus familiaris
538953 Bos taurus
100009374 Oryctolagus cuniculus
305858 Rattus norvegicus
399342 Xenopus laevis
30501 Danio rerio
18424 Mus musculus
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