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Geminin 抗体

(Geminin, DNA Replication Inhibitor (GMNN))
This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16. [provided by RefSeq, Oct 2011].
Geminin 抗体  (AA 110-209) Geminin 抗体  (AA 110-209) Geminin 抗体 (AA 110-209) (ABIN565518)

GMNN 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A8 unconjugated

Geminin 抗体  (AA 1-209) Geminin 抗体  (AA 1-209) Geminin 抗体 (AA 1-209) (ABIN6141186)

GMNN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

Geminin 抗体  (AA 50-100) Geminin 抗体  (AA 50-100) Geminin 抗体 (AA 50-100) (ABIN1574066)

GMNN 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

Geminin 抗体 by Grade

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Geminin 抗体 by 适用

Find Geminin 抗体 for a variety of species such as anti-Human Geminin, anti-Mouse Geminin, anti-Rat Geminin. The species listed below are among those available. Click on a link to go to the corresponding products.

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Geminin 抗体 by 抗原表位

Find Geminin 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Geminin 抗体 by 克隆形成能力

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Geminin 抗体 by 克隆

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Geminin 抗体 by 标记

Find Geminin 抗体 with a specific conjugate such as FITC, Biotin, APC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Geminin 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (7)
Cat. No. ABIN565518
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN6141186
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (1)
  • (2)
Cat. No. ABIN1574066
Quantity 40 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7444142
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, IF, StM
Validations
  • (3)
Cat. No. ABIN6940265
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), IF (p)
Validations
  • (2)
Cat. No. ABIN1387623
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7153777
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN526422
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN5013600
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7127514
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN5013598
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN651420
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF/ICC
Validations
  • (2)
Cat. No. ABIN1843722
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7153780
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7153778
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Geminin 抗体

Tsunematsu, Takihara, Ishimaru, Pagano, Takata, Kudo: "Aurora-A controls pre-replicative complex assembly and DNA replication by stabilizing geminin in mitosis." in: Nature communications, Vol. 4, pp. 1885, (2013) (PubMed).

Wang, Kirschner: "Emi1 preferentially inhibits ubiquitin chain elongation by the anaphase-promoting complex." in: Nature cell biology, Vol. 15, Issue 7, pp. 797-806, (2013) (PubMed).

Yim, Erikson: "Polo-like kinase 1 depletion induces DNA damage in early S prior to caspase activation." in: Molecular and cellular biology, Vol. 29, Issue 10, pp. 2609-21, (2009) (PubMed).

Pitulescu, Kessel, Luo: "The regulation of embryonic patterning and DNA replication by geminin." in: Cellular and molecular life sciences : CMLS, Vol. 62, Issue 13, pp. 1425-33, (2005) (PubMed).

Luo, Yang, Takihara, Knoetgen, Kessel: "The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions." in: Nature, Vol. 427, Issue 6976, pp. 749-53, (2004) (PubMed).

Montanari, Boninsegna, Faraglia, Coco, Giordano, Cittadini, Sgambato: "Increased expression of geminin stimulates the growth of mammary epithelial cells and is a frequent event in human tumors." in: Journal of cellular physiology, Vol. 202, Issue 1, pp. 215-22, (2004) (PubMed).

ElShamy, Livingston: "Identification of BRCA1-IRIS, a BRCA1 locus product." in: Nature cell biology, Vol. 6, Issue 10, pp. 954-67, (2004) (PubMed).

Eward, Obermann, Shreeram, Loddo, Fanshawe, Williams, Jung, Prevost, Blow, Stoeber, Williams: "DNA replication licensing in somatic and germ cells." in: Journal of cell science, Vol. 117, Issue Pt 24, pp. 5875-86, (2004) (PubMed).

Wohlschlegel, Dwyer, Dhar, Cvetic, Walter, Dutta: "Inhibition of eukaryotic DNA replication by geminin binding to Cdt1." in: Science (New York, N.Y.), Vol. 290, Issue 5500, pp. 2309-12, (2000) (PubMed).

Aliases for Geminin 抗体

geminin, DNA replication inhibitor (GMNN) 抗体
CG3183 gene product from transcript CG3183-RA (geminin) 抗体
geminin, DNA replication inhibitor (gmnn) 抗体
geminin (LOC410093) 抗体
GE24654 gene product from transcript GE24654-RA (Dyak\geminin) 抗体
geminin (Gmnn) 抗体
geminin, DNA replication inhibitor (Gmnn) 抗体
anon-WO0257455.1 抗体
AW546347 抗体
CG3183 抗体
Dmel\\CG3183 抗体
Dm Geminin 抗体
Dm geminin 抗体
DyakGE24654 抗体
dyak_GLEANR_833 抗体
GB16871 抗体
GE24654 抗体
Gem 抗体
gem 抗体
Geminin 抗体
geminin 抗体
GMNN 抗体
l(2)k14019 抗体
LOC100049517 抗体
sb:cb254 抗体
v(2)k09107 抗体
zgc:66217 抗体
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