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XRCC5 抗体

(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008].
XRCC5 抗体  (AA 1-732) XRCC5 抗体  (AA 1-732) XRCC5 抗体 (AA 1-732) (ABIN563391)

XRCC5 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3D8 unconjugated

XRCC5 抗体  (AA 543-732) XRCC5 抗体  (AA 543-732) XRCC5 抗体 (AA 543-732) (ABIN6150309)

XRCC5 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

XRCC5 抗体 XRCC5 抗体 XRCC5 抗体 (ABIN7010873)

XRCC5 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

XRCC5 抗体 by Grade

Find XRCC5 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

XRCC5 抗体 by 适用

Find XRCC5 抗体 for a variety of species such as anti-Human XRCC5, anti-Mouse XRCC5, anti-Monkey XRCC5. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find XRCC5 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

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Find XRCC5 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular XRCC5 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (3)
  • (6)
Cat. No. ABIN563391
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (2)
  • (12)
Cat. No. ABIN6150309
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (6)
Cat. No. ABIN7010873
Quantity 60 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, ELISA, FACS, ICC
Validations
  • (2)
  • (5)
Cat. No. ABIN969463
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), ICC
Validations
  • (6)
Cat. No. ABIN3044235
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IP
Validations
  • (4)
Cat. No. ABIN7175897
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (4)
Cat. No. ABIN7127596
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN6150308
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (4)
Cat. No. ABIN7271406
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN2778271
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, FACS
Validations
  • (5)
Cat. No. ABIN3029653
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7175904
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP, ICC
Validations
  • (3)
Cat. No. ABIN6241745
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC
Validations
  • (3)
Cat. No. ABIN7477623
Quantity 1 mL
Datasheet Datasheet
Reactivity Human
Application WB, IF, FACS
Validations
  • (4)
Cat. No. ABIN655900
Quantity 400 μL
Datasheet Datasheet

Latest Publications for our XRCC5 抗体

Assani, Segbo, Yu, Yessoufou, Xiong, Zhou, Zhou: "Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 20, Issue 12, pp. 3679-3687, (2020) (PubMed).

Zhang, Chang, Sun, Chen, Yang, Tang, Jing, Kang, He, Wu, Wei, Wang, Xu, Zhu, Shen, Zeng, Wang, Liu, Zhang, Mao, Jiang, Sun: "Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability." in: Journal of cell science, Vol. 131, Issue 12, (2018) (PubMed).

Oing, Tennstedt, Simon, Volquardsen, Borgmann, Bokemeyer, Petersen, Dikomey, Rothkamm, Mansour: "BCL2-overexpressing prostate cancer cells rely on PARP1-dependent end-joining and are sensitive to combined PARP inhibitor and radiation therapy." in: Cancer letters, Vol. 423, pp. 60-70, (2018) (PubMed).

Li, Zhang, Chen, Guo, Zhang, Tang, Xu, Zhang, Tao, Wang, Jiang, Sun, Mao: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).

Hori, Someya, Matsumoto, Nakata, Kitagawa, Hasegawa, Tsuchiya, Fukushima, Gocho, Sato, Ohnuma, Kato, Sugita, Hasegawa, Sakata: "Influence of XRCC4 expression in esophageal cancer cells on the response to radiotherapy." in: Medical molecular morphology, Vol. 50, Issue 1, pp. 25-33, (2016) (PubMed).

Hasegawa, Someya, Hori, Matsumoto, Nakata, Nojima, Kitagawa, Tsuchiya, Masumori, Hasegawa, Sakata: "Expression of Ku70 predicts results of radiotherapy in prostate cancer." in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], Vol. 193, Issue 1, pp. 29-37, (2016) (PubMed).

Nomura, Sogawa, Noda, Seimiya, Matsushita, Miura, Tomonaga, Yoshitomi, Imazeki, Takizawa, Mogushi, Miyazaki, Yokosuka: "Serum anti-Ku86 is a potential biomarker for early detection of hepatitis C virus-related hepatocellular carcinoma." in: Biochemical and biophysical research communications, Vol. 421, Issue 4, pp. 837-43, (2012) (PubMed).

Nolens, Pignon, Koopmansch, Elmoualij, Zorzi, De Pauw, Winkler: "Ku proteins interact with activator protein-2 transcription factors and contribute to ERBB2 overexpression in breast cancer cell lines." in: Breast cancer research : BCR, Vol. 11, Issue 6, pp. R83, (2010) (PubMed).

Dedieu, Canron, Rezvani, Bouchecareilh, Mazurier, Sinisi, Zanda, Moenner, Bikfalvi, North: "The cytoprotective drug amifostine modifies both expression and activity of the pro-angiogenic factor VEGF-A." in: BMC medicine, Vol. 8, pp. 19, (2010) (PubMed).

Heemers, Regan, Schmidt, Anderson, Ballman, Tindall: "Androgen modulation of coregulator expression in prostate cancer cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 23, Issue 4, pp. 572-83, (2009) (PubMed).

Aliases for XRCC5 抗体

X-ray repair cross complementing 5 (XRCC5) 抗体
X-ray repair complementing defective repair in Chinese hamster cells 5 (Xrcc5) 抗体
X-ray repair cross complementing 5 (Xrcc5) 抗体
X-ray repair complementing defective repair in Chinese hamster cells 5 L homeolog (xrcc5.L) 抗体
AI314015 抗体
KARP-1 抗体
KARP1 抗体
Ku80 抗体
KU80 抗体
Ku86 抗体
KUB2 抗体
Kup80 抗体
NFIV 抗体
XRCC5 抗体
xrcc5-a 抗体
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