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RECQL2 抗体

(Werner syndrome RecQ like helicase (WRN))
This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging. [provided by RefSeq, Jul 2008].
RECQL2 抗体  (AA 1322-1432) RECQL2 抗体  (AA 1322-1432) RECQL2 抗体 (AA 1322-1432) (ABIN521400)

WRN 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C11 unconjugated

RECQL2 抗体  (Internal Region) RECQL2 抗体  (Internal Region) RECQL2 抗体 (Internal Region) (ABIN6266052)

WRN 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

RECQL2 抗体  (Center) RECQL2 抗体  (Center) RECQL2 抗体 (Center) (ABIN2854925)

WRN 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

RECQL2 抗体 by 适用

Find RECQL2 抗体 for a variety of species such as anti-Human RECQL2, anti-Mouse RECQL2, anti-Rat RECQL2. The species listed below are among those available. Click on a link to go to the corresponding products.

RECQL2 抗体 by 应用范围

Find RECQL2 抗体 validated for a specific application such as WB, ELISA, FACS, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

RECQL2 抗体 by 抗体来源

Find RECQL2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

RECQL2 抗体 by 抗原表位

Find RECQL2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

RECQL2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal RECQL2 抗体. Click on a link to go to the corresponding products.

RECQL2 抗体 by 克隆

Find RECQL2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

RECQL2 抗体 by 标记

Find RECQL2 抗体 with a specific conjugate such as Biotin, APC, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular RECQL2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN521400
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6266052
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC, IHC (p)
Validations
  • (3)
Cat. No. ABIN2854925
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, ICC
Validations
  • (1)
  • (3)
Cat. No. ABIN2668372
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN656017
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7254655
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN521399
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN563387
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6150263
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, EIA
Validations
  • (2)
Cat. No. ABIN955584
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN6989653
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
Cat. No. ABIN7182989
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
Cat. No. ABIN6280780
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application IHC
Validations
Cat. No. ABIN7448866
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
Cat. No. ABIN7450969
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our RECQL2 抗体

Hayashi, Tasaka, Kondo, Ishikawa, Goto, Matsuhashi, Sadahira, Sugihara, Wada: "Successful Cord Blood Transplantation in a Werner Syndrome Patient with High-risk Myelodysplastic Syndrome." in: Internal medicine (Tokyo, Japan), Vol. 58, Issue 1, pp. 109-113, (2019) (PubMed).

Chan, Shibue, McFarland, Gaeta, Ghandi, Dumont, Gonzalez, McPartlan, Li, Zhang, Bin Liu, Lazaro, Gu, Piett, Apffel, Ali, Deasy, Keskula, Ng, Roberts, Reznichenko, Leung, Alimova, Schenone, Islam et al.: "WRN helicase is a synthetic lethal target in microsatellite unstable cancers. ..." in: Nature, Vol. 568, Issue 7753, pp. 551-556, (2019) (PubMed).

Kawakubo-Yasukochi, Morioka, Hazekawa, Yasukochi, Nishinakagawa, Ono, Kawano, Nakamura, Nakashima: "miR-200c-3p spreads invasive capacity in human oral squamous cell carcinoma microenvironment." in: Molecular carcinogenesis, Vol. 57, Issue 2, pp. 295-302, (2018) (PubMed).

Thangavel, Berti, Levikova, Pinto, Gomathinayagam, Vujanovic, Zellweger, Moore, Lee, Hendrickson, Cejka, Stewart, Lopes, Vindigni: "DNA2 drives processing and restart of reversed replication forks in human cells." in: The Journal of cell biology, Vol. 208, Issue 5, pp. 545-62, (2015) (PubMed).

Maddukuri, Ketkar, Eddy, Zafar, Eoff: "The Werner syndrome protein limits the error-prone 8-oxo-dG lesion bypass activity of human DNA polymerase kappa." in: Nucleic acids research, Vol. 42, Issue 19, pp. 12027-40, (2014) (PubMed).

Sidorova, Kehrli, Mao, Monnat: "Distinct functions of human RECQ helicases WRN and BLM in replication fork recovery and progression after hydroxyurea-induced stalling." in: DNA repair, Vol. 12, Issue 2, pp. 128-39, (2013) (PubMed).

Bétous, Glick, Zhao, Cortez: "Identification and characterization of SMARCAL1 protein complexes." in: PLoS ONE, Vol. 8, Issue 5, pp. e63149, (2013) (PubMed).

Indig, Rybanska, Karmakar, Devulapalli, Fu, Carrier, Bohr: "Nucleolin inhibits G4 oligonucleotide unwinding by Werner helicase." in: PLoS ONE, Vol. 7, Issue 6, pp. e35229, (2012) (PubMed).

Maddukuri, Ketkar, Eddy, Zafar, Griffin, Eoff: "Enhancement of human DNA polymerase η activity and fidelity is dependent upon a bipartite interaction with the Werner syndrome protein." in: The Journal of biological chemistry, Vol. 287, Issue 50, pp. 42312-23, (2012) (PubMed).

Thangavel, Mendoza-Maldonado, Tissino, Sidorova, Yin, Wang, Monnat, Falaschi, Vindigni: "Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation." in: Molecular and cellular biology, Vol. 30, Issue 6, pp. 1382-96, (2010) (PubMed).

Aliases for RECQL2 抗体

Werner syndrome RecQ like helicase (WRN) 抗体
mediator of RNA polymerase II transcription subunit 34 (LOC9327212) 抗体
Bloom syndrome RecQ like helicase (blm) 抗体
Werner syndrome RecQ like helicase (Wrn) 抗体
Werner syndrome, RecQ helicase-like L homeolog (wrn.L) 抗体
AI846146 抗体
ffa-1 抗体
recq2 抗体
RECQ3 抗体
RECQL2 抗体
recql2 抗体
RECQL3 抗体
recql3 抗体
RGD1564788 抗体
xBLM 抗体
xwrn 抗体
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