Mre11 抗体
(MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog\; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
recommended
recommended
MRE11A 适用: 人, 大鼠, 小鼠, 小鸡, Hamster WB, IHC, IF, IP, ICC, ChIP, FACS 宿主: 兔 Polyclonal unconjugated
recommended
MRE11A 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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Find available monoclonal or polyclonal Mre11 抗体. Click on a link to go to the corresponding products.
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Cat. No.
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Human
Application
WB, IHC, IF, IP
Validations
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- (4)
Cat. No.
ABIN3016250
Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IF, IP, ICC, ChIP, FACS
Validations
- (5)
Cat. No.
ABIN363310
Quantity
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Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
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Cat. No.
ABIN747293
Quantity
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Cat. No.
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Quantity
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Application
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Cat. No.
ABIN7150623
Quantity
100 μL
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Reactivity
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Application
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Validations
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Cat. No.
ABIN7150624
Quantity
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Datasheet
Datasheet
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Application
WB, ELISA, IHC, IF, ICC
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Cat. No.
ABIN6263351
Quantity
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Datasheet
Datasheet
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Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Application
WB, ELISA, IHC
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Cat. No.
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Quantity
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Datasheet
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Application
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Cat. No.
ABIN518014
Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IF, IP, IC
Validations
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
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Validations
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Quantity
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Datasheet
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Latest Publications for our Mre11 抗体
: "MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining." in: Molecular cell, Vol. 71, Issue 2, pp. 332-342.e8, (2019) (PubMed).: "Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination." in: Nature communications, Vol. 9, Issue 1, pp. 3872, (2019) (PubMed).
: "Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation." in: Nucleic acids research, Vol. 47, Issue 8, pp. 4068-4085, (2019) (PubMed).
: "UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. ..." in: Cell, Vol. 176, Issue 3, pp. 505-519.e22, (2019) (PubMed).
: "PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis." in: Cell reports, Vol. 26, Issue 5, pp. 1333-1343.e7, (2019) (PubMed).
: "Hypoosmotic stress induces R loop formation in nucleoli and ATR/ATM-dependent silencing of nucleolar transcription." in: Nucleic acids research, Vol. 47, Issue 13, pp. 6811-6825, (2019) (PubMed).
: "C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex." in: Molecular cell, (2019) (PubMed).
: "Increased error-free DNA repair gene expression through reprogramming in human iPS cells." in: Regenerative therapy, Vol. 11, pp. 101-105, (2019) (PubMed).
: "Rat Glioma Cell-Based Functional Characterization of Anti-Stress and Protein Deaggregation Activities in the Marine Carotenoids, Astaxanthin and Fucoxanthin." in: Marine drugs, Vol. 17, Issue 3, (2019) (PubMed).
: "Nanostructure of Clustered DNA Damage in Leukocytes after In-Solution Irradiation with the Alpha Emitter Ra-223." in: Cancers, Vol. 11, Issue 12, (2019) (PubMed).
Aliases for Mre11 抗体
MRE11 homolog A, double strand break repair nuclease (mre11a) 抗体MRE11 homolog, double strand break repair nuclease (MRE11) 抗体
MRE11A homolog A, double strand break repair nuclease (Mre11a) 抗体
MRE11 homolog A, double strand break repair nuclease (Mre11a) 抗体
ATLD 抗体
HNGS1 抗体
Mre11 抗体
MRE11 抗体
Mre11b 抗体
MRE11B 抗体
wu:faa63d12 抗体
zgc:64018 抗体
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