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Minichromosome Maintenance Deficient 4 抗体

(Minichromosome Maintenance Deficient 4 (MCM4))
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008].
MCM4 抗体  (AA 1-863) MCM4 抗体  (AA 1-863) MCM4 抗体 (AA 1-863) (ABIN950014)

MCM4 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

MCM4 抗体  (AA 1-863) MCM4 抗体  (AA 1-863) MCM4 抗体 (AA 1-863) (ABIN517777)

MCM4 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Polyclonal unconjugated

MCM4 抗体 MCM4 抗体 MCM4 抗体 (ABIN7074631)

MCM4 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

Minichromosome Maintenance Deficient 4 抗体 by 适用

Find Minichromosome Maintenance Deficient 4 抗体 for a variety of species such as anti-Human Minichromosome Maintenance Deficient 4, anti-Mouse Minichromosome Maintenance Deficient 4, anti-Rat Minichromosome Maintenance Deficient 4. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find Minichromosome Maintenance Deficient 4 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find Minichromosome Maintenance Deficient 4 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

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Minichromosome Maintenance Deficient 4 抗体 by 标记

Find Minichromosome Maintenance Deficient 4 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Minichromosome Maintenance Deficient 4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (7)
Cat. No. ABIN950014
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IF
Validations
  • (6)
Cat. No. ABIN517777
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7074631
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (3)
Cat. No. ABIN7150334
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7242281
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN3031812
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN561762
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (1)
Cat. No. ABIN6143642
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN203262
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN203261
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Human, Monkey
Application WB
Validations
  • (1)
Cat. No. ABIN203260
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6747321
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7268545
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN1532597
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN2774884
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our Minichromosome Maintenance Deficient 4 抗体

Song, Lafont, Chen, Wu, Shirahige, Rankin: "Cohesin acetylation promotes sister chromatid cohesion only in association with the replication machinery." in: The Journal of biological chemistry, Vol. 287, Issue 41, pp. 34325-36, (2012) (PubMed).

Orr, Gaymes, Ladon, Chronis, Czepulkowski, Wang, Mufti, Marcotte, Thomas: "Reducing MCM levels in human primary T cells during the G(0)-->G(1) transition causes genomic instability during the first cell cycle." in: Oncogene, Vol. 29, Issue 26, pp. 3803-14, (2010) (PubMed).

Tsuruga, Yabuta, Hashizume, Ikeda, Endo, Nojima: "Expression, nuclear localization and interactions of human MCM/P1 proteins." in: Biochemical and biophysical research communications, Vol. 236, Issue 1, pp. 118-25, (1997) (PubMed).

Musahl, Schulte, Burkhart, Knippers: "A human homologue of the yeast replication protein Cdc21. Interactions with other Mcm proteins." in: European journal of biochemistry / FEBS, Vol. 230, Issue 3, pp. 1096-101, (1995) (PubMed).

Hu, Burkhart, Schulte, Musahl, Knippers: "The P1 family: a new class of nuclear mammalian proteins related to the yeast Mcm replication proteins." in: Nucleic acids research, Vol. 21, Issue 23, pp. 5289-93, (1994) (PubMed).

Coxon, Maundrell, Kearsey: "Fission yeast cdc21+ belongs to a family of proteins involved in an early step of chromosome replication." in: Nucleic acids research, Vol. 20, Issue 21, pp. 5571-7, (1993) (PubMed).

Koonin: "A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication." in: Nucleic acids research, Vol. 21, Issue 11, pp. 2541-7, (1993) (PubMed).

Aliases for Minichromosome Maintenance Deficient 4 抗体

minichromosome maintenance complex component 4 L homeolog (mcm4.L) 抗体
minichromosome maintenance complex component 4 S homeolog (mcm4.S) 抗体
minichromosome maintenance complex component 4 (MCM4) 抗体
minichromosome maintenance complex component 4 (mcm4) 抗体
minichromosome maintenance complex component 4 (Mcm4) 抗体
19G 抗体
AI325074 抗体
AU045576 抗体
cb1025 抗体
cdc21 抗体
CDC21 抗体
Cdc21 抗体
CDC54 抗体
fc12c09 抗体
fj85g09 抗体
hCdc21 抗体
hm:zeh1616 抗体
mcdc21 抗体
Mcmd4 抗体
mKIAA4003 抗体
NKCD 抗体
NKGCD 抗体
P1-CDC21 抗体
wu:fc12c09 抗体
wu:fj85g09 抗体
zeh1616 抗体
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