anti-LIG3 (LIG3) 抗体产品概述

Full name:
anti-Ligase III, DNA, ATP-Dependent 抗体 (LIG3)
在www.antibodies-online.cn可供68 Ligase III, DNA, ATP-Dependent (LIG3) 抗体的17不同的供货商。 再加上,我们可以发LIG3 试剂盒 (6)LIG3 蛋白 (5)和数多这个蛋白质的别的产品。 总共83 LIG3产品已列进来了。
别名:
An02g06890, AO090003000668, D11Wsu78e, DDBDRAFT_0218523, DDBDRAFT_0232266, DDB_0218523, DDB_0232266, LIG2, LIG3, orf36, wu:fb12c02, wu:fd10b03, wu:fm79b09
列出全部抗体 基因 基因ID UniProt
LIG3 3980 P49916
LIG3 303369  
LIG3 16882  

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抗Human LIG3 抗体:

抗Rat (Rattus) LIG3 抗体:

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引用最多的anti-LIG3 抗体

  1. Chicken Monoclonal LIG3 Primary Antibody for BP, ICC - ABIN445494 : Leppard, Dong, Mackey, Tomkinson: Physical and functional interaction between DNA ligase IIIalpha and poly(ADP-Ribose) polymerase 1 in DNA single-strand break repair. in Molecular and cellular biology 2003 (PubMed)
    Show all 10 references for 445494

  2. Human Monoclonal LIG3 Primary Antibody for ICC, IF - ABIN151084 : Klungland, Hoess, Gunz, Constantinou, Clarkson, Doetsch, Bolton, Wood, Lindahl: Base excision repair of oxidative DNA damage activated by XPG protein. in Molecular cell 1999 (PubMed)
    Show all 8 references for 151084

  3. Dog (Canine) Monoclonal LIG3 Primary Antibody for IF, WB - ABIN968692 : Chen, Tomkinson, Ramos, Mackey, Danehower, Walter, Schultz, Besterman, Husain: Mammalian DNA ligase III: molecular cloning, chromosomal localization, and expression in spermatocytes undergoing meiotic recombination. in Molecular and cellular biology 1995 (PubMed)
    Show all 4 references for 968692

  4. Human Polyclonal LIG3 Primary Antibody for ICC, IF - ABIN4305495 : Fan, Li, Small, Rassool: Cells expressing FLT3/ITD mutations exhibit elevated repair errors generated through alternative NHEJ pathways: implications for genomic instability and therapy. in Blood 2010 (PubMed)
    Show all 2 references for 4305495

  5. Mouse (Murine) Polyclonal LIG3 Primary Antibody for IHC, WB - ABIN3022649 : Xu, Zhang, Zhang, Meng, Zhang, Jiang, Xu, Van Meter, Seluanov, Gorbunova, Mao: SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner. in Cell cycle (Georgetown, Tex.) 2015 (PubMed)

  6. Human Polyclonal LIG3 Primary Antibody for EIA, WB - ABIN951931 : Cotner-Gohara, Kim, Hammel, Tainer, Tomkinson, Ellenberger: Human DNA ligase III recognizes DNA ends by dynamic switching between two DNA-bound states. in Biochemistry 2010 (PubMed)

更多抗LIG3的相互作用对抗体

Human Ligase III, DNA, ATP-Dependent (LIG3) interaction partners

  1. The g.29661G>A and g.29059C>T polymorphisms of LIG3 may play a role in the keratoconus and Fuchs endothelial corneal dystrophy pathogenesis and can be considered as markers in these diseases.

  2. A computational approach to determine susceptibility to cancer by evaluating the deleterious effect of nsSNP in XRCC1 (显示 XRCC1 抗体) gene on binding interaction of XRCC1 (显示 XRCC1 抗体) protein with ligase III.

  3. In the context of tyrosine kinase (显示 TXK 抗体)-activated leukemias, c-MYC (显示 MYC 抗体) contributes to aberrant DNA repair through downstream targets LIG3 and PARP1 (显示 PARP1 抗体) up-regulation.

  4. there is an absolute requirement for fully functional DNA ligase III (LIG3), but not ligase IV (LIG4 (显示 LIG4 抗体)), to facilitate the escape from a telomere-driven crisis.

  5. Results show that overexpression of DNA ligase III in mitochondria improves mitochondrial base excision repair and enhances cell survival after oxidative stress.

  6. data confirm previous work showing that Lig3 is required to maintain mtDNA integrity and function, and highlight a new function of ATM (显示 ATM 抗体) in regulating DNA Lig3 stability and consequently mtDNA repair

  7. Human Mre11 (显示 MRE11A 抗体)/human Rad50 (显示 RAD50 抗体)/Nbs1 (显示 NBN 抗体) and DNA ligase IIIalpha/XRCC1 (显示 XRCC1 抗体) protein complexes act together in an alternative nonhomologous end joining pathway.

  8. Using our cohort of 480 breast cancer patients, we provide replicated evidence that a polymorphism near the LIG3 gene is associated with acute skin toxicity following radiotherapy.

  9. results establish a role for Lig3 in mitochondria, but distinguish it from its interacting protein Xrcc1 (显示 XRCC1 抗体)

  10. The collective results support a "jackknife model" in which the ZnF (显示 ZNF629 抗体) loads ligase III onto nicked DNA and conformational changes deliver DNA into the active site.

Mouse (Murine) Ligase III, DNA, ATP-Dependent (LIG3) interaction partners

  1. Results show that overexpression of DNA ligase III in mitochondria improves mitochondrial base excision repair and enhances cell survival after oxidative stress.

  2. data confirm previous work showing that Lig3 is required to maintain mtDNA integrity and function, and highlight a new function of ATM (显示 ATM 抗体) in regulating DNA Lig3 stability and consequently mtDNA repair

  3. Lig3 has an essential role in mtDNA maintenance but is dispensable for the viability of cultured cells

  4. data reveal that the critical biological role of Lig3 is to maintain mtDNA integrity and not Xrcc1 (显示 XRCC1 抗体)-dependent DNA repair

  5. results establish a role for Lig3 in mitochondria, but distinguish it from its interacting protein Xrcc1 (显示 XRCC1 抗体)

  6. Early embryonic lethality is due to targeted inactivation of DNA ligase III.

LIG3 抗原简介

Antigen Summary

This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with LIG3

  • ligase III, DNA, ATP-dependent (lig3) 抗体
  • ligase III, DNA, ATP-dependent (LIG3) 抗体
  • DNA ligase III (orf36) 抗体
  • DNA ligase 3 (ANI_1_2644024) 抗体
  • DNA ligase 3 (AOR_1_1174154) 抗体
  • DNA ligase III (Bm1_22840) 抗体
  • BRCT domain-containing protein (lig3) 抗体
  • ligase III, DNA, ATP-dependent (Lig3) 抗体
  • An02g06890 抗体
  • AO090003000668 抗体
  • D11Wsu78e 抗体
  • DDBDRAFT_0218523 抗体
  • DDBDRAFT_0232266 抗体
  • DDB_0218523 抗体
  • DDB_0232266 抗体
  • LIG2 抗体
  • LIG3 抗体
  • orf36 抗体
  • wu:fb12c02 抗体
  • wu:fd10b03 抗体
  • wu:fm79b09 抗体

Protein level used designations for LIG3

ligase III, DNA, ATP-dependent , DNA ligase 3 , DNA ligase (ATP) 3 , DNA ligase 3 isoform alpha , DNA ligase III , DNA ligase 3-like , ligase II, DNA, ATP-dependent , polydeoxyribonucleotide synthase [ATP] 3

GENE ID SPECIES
336509 Danio rerio
417530 Gallus gallus
454581 Pan troglodytes
491145 Canis lupus familiaris
514719 Bos taurus
549105 Xenopus (Silurana) tropicalis
715181 Macaca mulatta
955080 Heliothis zea virus 1
4979178 Aspergillus niger CBS 513.88
5991803 Aspergillus oryzae RIB40
6099475 Brugia malayi
8624245 Dictyostelium discoideum AX4
100071671 Equus caballus
100344941 Oryctolagus cuniculus
100405358 Callithrix jacchus
100455958 Pongo abelii
100464510 Ailuropoda melanoleuca
100634887 Amphimedon queenslandica
3980 Homo sapiens
303369 Rattus norvegicus
16882 Mus musculus
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