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BRCC3 抗体

(BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3))
This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response, where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains, and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya, a cerebrovascular angiopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jun 2011].
BRCC3 抗体  (AA 14-316) BRCC3 抗体  (AA 14-316) BRCC3 抗体 (AA 14-316) (ABIN7158679)

BRCC3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

BRCC3 抗体  (AA 1-316) BRCC3 抗体  (AA 1-316) BRCC3 抗体 (AA 1-316) (ABIN7158678)

BRCC3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

BRCC3 抗体  (AA 1-316) BRCC3 抗体  (AA 1-316) BRCC3 抗体 (AA 1-316) (ABIN462274)

BRCC3 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal AT3B1 unconjugated

BRCC3 抗体 by 适用

Find BRCC3 抗体 for a variety of species such as anti-Human BRCC3, anti-Mouse BRCC3, anti-Rat BRCC3. The species listed below are among those available. Click on a link to go to the corresponding products.

BRCC3 抗体 by 应用范围

Find BRCC3 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

BRCC3 抗体 by 抗体来源

Find BRCC3 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

BRCC3 抗体 by 抗原表位

Find BRCC3 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

BRCC3 抗体 by 克隆形成能力

Find available monoclonal or polyclonal BRCC3 抗体. Click on a link to go to the corresponding products.

BRCC3 抗体 by 克隆

Find BRCC3 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

BRCC3 抗体 by 标记

Find BRCC3 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular BRCC3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (4)
Cat. No. ABIN7158679
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7158678
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN462274
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), EIA
Validations
  • (4)
Cat. No. ABIN400864
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN949635
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6243066
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6243065
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, ICC
Validations
  • (1)
Cat. No. ABIN5649331
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN2590581
Quantity 100 μg
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6747830
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Horse, Human, Monkey, Pig, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6747829
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN1866942
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB, IF
Validations
  • (2)
Cat. No. ABIN2788976
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN499495
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
Cat. No. ABIN872718
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our BRCC3 抗体

Xu, Moresco, Chang, Mukim, Smith, Diedrich, Yates, Jones: "SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy." in: PLoS pathogens, Vol. 14, Issue 5, pp. e1007071, (2018) (PubMed).

Chen, Arciero, Wang, Broccoli, Godwin: "BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and nuclear foci formation." in: Cancer research, Vol. 66, Issue 10, pp. 5039-46, (2006) (PubMed).

Dong, Hakimi, Chen, Kumaraswamy, Cooch, Godwin, Shiekhattar: "Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair." in: Molecular cell, Vol. 12, Issue 5, pp. 1087-99, (2003) (PubMed).

Aliases for BRCC3 抗体

BRCA1/BRCA2-containing complex subunit 3 (BRCC3) 抗体
DEP domain containing 1B (depdc1b) 抗体
BRCA1/BRCA2-containing complex subunit 3 (brcc3) 抗体
BRCA1/BRCA2-containing complex, subunit 3 (Brcc3) 抗体
BRCA1/BRCA2-containing complex subunit 3 L homeolog (brcc3.L) 抗体
BRCC3 抗体
brcc3 抗体
BRCC36 抗体
brcc36 抗体
C6.1A 抗体
CXorf53 抗体
xtp1 抗体
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