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BRCA2 抗体

(Breast Cancer 2, Early Onset (BRCA2))
Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq, Dec 2008].
BRCA2 抗体  (AA 21-130) BRCA2 抗体  (AA 21-130) BRCA2 抗体 (AA 21-130) (ABIN673434)

BRCA2 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

BRCA2 抗体 BRCA2 抗体 BRCA2 抗体 (ABIN7234156)

BRCA2 适用: 人, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

BRCA2 抗体  (AA 2990-3232) BRCA2 抗体  (AA 2990-3232) BRCA2 抗体 (AA 2990-3232) (ABIN7433543)

BRCA2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

BRCA2 抗体 by 适用

Find BRCA2 抗体 for a variety of species such as anti-Human BRCA2, anti-Rat BRCA2, anti-Mouse BRCA2. The species listed below are among those available. Click on a link to go to the corresponding products.

BRCA2 抗体 by 应用范围

Find BRCA2 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

BRCA2 抗体 by 抗体来源

Find BRCA2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

BRCA2 抗体 by 抗原表位

Find BRCA2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

BRCA2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal BRCA2 抗体. Click on a link to go to the corresponding products.

BRCA2 抗体 by 克隆

Find BRCA2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

BRCA2 抗体 by 标记

Find BRCA2 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular BRCA2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
  • (1)
Cat. No. ABIN673434
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN7234156
Quantity 200 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7433543
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN560095
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN3016069
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN5013248
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (1)
Cat. No. ABIN7433540
Quantity 100 μL
Datasheet Datasheet
Reactivity Zebrafish (Danio rerio)
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7179702
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7138558
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6242777
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IC
Validations
  • (2)
Cat. No. ABIN7306984
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Rat
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN7299116
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN673436
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN7090792
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN885444
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our BRCA2 抗体

Whelan, Lee, Yin, Ofri, Bermudez-Hernandez, Keegan, Fenyo, Rothenberg: "Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks." in: Nature communications, Vol. 9, Issue 1, pp. 3882, (2019) (PubMed).

Chang, Zhang, Chang, Song, Qin, Chang, Guo, Wei: "Expression characteristics of FHIT, p53, BRCA2 and MLH1 in families with a history of oesophageal cancer in a region with a high incidence of oesophageal cancer." in: Oncology letters, Vol. 9, Issue 1, pp. 430-436, (2015) (PubMed).

Moeller, Yordy, Williams, Giri, Raju, Molkentine, Byers, Heymach, Story, Lee, Sturgis, Weber, Garden, Ang, Schwartz: "DNA repair biomarker profiling of head and neck cancer: Ku80 expression predicts locoregional failure and death following radiotherapy." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 7, pp. 2035-43, (2011) (PubMed).

Bernard-Gallon, Dechelotte, Le Corre, Chalabi, Vissac-Sabatier, Bignon: "Differential expressions of BRCA1 and BRCA2 in infantile gynecomastia." in: Anticancer research, Vol. 24, Issue 1, pp. 321-4, (2004) (PubMed).

Bernard-Gallon, Déchelotte, Vissac, Aunoble, Cravello, Malpuech, Bignon: "BRCA1 and BRCA2 protein expressions in an ovotestis of a 46, XX true hermaphrodite." in: Breast cancer research : BCR, Vol. 3, Issue 1, pp. 61-5, (2001) (PubMed).

Wu, Jiang, Thangaraju, Wu, Couch: "Induction of the BRCA2 promoter by nuclear factor-kappa B." in: The Journal of biological chemistry, Vol. 275, Issue 45, pp. 35548-56, (2000) (PubMed).

Sergeeva, Ershova, Veiko, Malinovskaya, Kalyanov, Kameneva, Stukalov, Dolgikh, Konkova, Ermakov, Veiko, Izhevskaya, Kutsev, Kostyuk: "Low-Dose Ionizing Radiation Affects Mesenchymal Stem Cells via Extracellular Oxidized Cell-Free DNA: A Possible Mediator of Bystander Effect and Adaptive Response." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 9515809 (PubMed).

Aliases for BRCA2 抗体

BRCA2, DNA repair associated (BRCA2) 抗体
Breast cancer 2, early onset homolog (Brca2) 抗体
BRCA2, DNA repair associated (Brca2) 抗体
breast cancer 2, early onset (brca2) 抗体
breast cancer 2, early onset (LOC584780) 抗体
BRCA2, DNA repair associated (brca2) 抗体
breast cancer 2, early onset (Brca2) 抗体
30169 抗体
AI256696 抗体
AW045498 抗体
BcDNA:SD25109 抗体
brca2 抗体
BRCA2 抗体
BRCC2 抗体
brcc2 抗体
BROVCA2 抗体
brovca2 抗体
CG13583 抗体
CG13584 抗体
CG30169 抗体
dmbrca2 抗体
Dmel\\CG30169 抗体
FACD 抗体
facd 抗体
FAD 抗体
fad 抗体
FAD1 抗体
fad1 抗体
FANCB 抗体
fancb 抗体
FANCD 抗体
FANCD1 抗体
fancd1 抗体
Fancd1 抗体
GLM3 抗体
PNCA2 抗体
RAB163 抗体
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