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APEX1 抗体

(Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene\; all encode the same protein. [provided by RefSeq, Jul 2008].
APEX1 抗体  (AA 1-318) APEX1 抗体  (AA 1-318) APEX1 抗体 (AA 1-318) (ABIN513392)

APEX1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated

APEX1 抗体  (AA 1-242) APEX1 抗体  (AA 1-242) APEX1 抗体 (AA 1-242) (ABIN1490625)

APEX1 适用: 人, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1H9 unconjugated

APEX1 抗体  (AA 219-318) APEX1 抗体  (AA 219-318) APEX1 抗体 (AA 219-318) (ABIN5611191)

APEX1 适用: 人, 大鼠, 猴 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 7A2G7 unconjugated

APEX1 抗体 by Grade

Find APEX1 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

APEX1 抗体 by 适用

Find APEX1 抗体 for a variety of species such as anti-Human APEX1, anti-Mouse APEX1, anti-Rat APEX1. The species listed below are among those available. Click on a link to go to the corresponding products.

APEX1 抗体 by 应用范围

Find APEX1 抗体 validated for a specific application such as WB, ELISA, IHC (p), IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

APEX1 抗体 by 抗体来源

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APEX1 抗体 by 抗原表位

Find APEX1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

APEX1 抗体 by 克隆形成能力

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APEX1 抗体 by 克隆

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APEX1 抗体 by 标记

Find APEX1 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular APEX1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (6)
Cat. No. ABIN513392
Quantity 50 μg
Datasheet Datasheet
Reactivity Dog, Human, Monkey
Application WB, IHC, IHC (p)
Validations
  • (8)
Cat. No. ABIN1490625
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Rat
Application WB, ELISA, IHC, ICC, FACS, Neut
Validations
  • (8)
Cat. No. ABIN5611191
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (5)
Cat. No. ABIN947565
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (7)
Cat. No. ABIN3043785
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (4)
Cat. No. ABIN6242774
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN3181880
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (4)
Cat. No. ABIN6136981
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6259977
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rabbit, Rat
Application WB, IHC, IF, ICC, IP, ChIP, Neut
Validations
  • (5)
Cat. No. ABIN363379
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, ChIP
Validations
  • (3)
Cat. No. ABIN7150355
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (3)
Cat. No. ABIN2857038
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN604869
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN184704
Quantity 100 μg
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN1490626
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our APEX1 抗体

Song, Zeng, Roychoudhury, Biswas, Mohapatra, Ray, Dowlatshahi, Wang, Band, Talmon, Bhakat: "Targeting Histone Chaperone FACT Complex Overcomes 5-Fluorouracil Resistance in Colon Cancer." in: Molecular cancer therapeutics, Vol. 19, Issue 1, pp. 258-269, (2020) (PubMed).

Zhang, Chao, Patil, Qin, Tiwari, Chiou, Dobin, Tsai, Li, Dang, Gupta, Urdahl, Nizet, Gingeras, Gaulton, Rana: "The long noncoding RNA ROCKI regulates inflammatory gene expression." in: The EMBO journal, Vol. 38, Issue 8, (2019) (PubMed).

Frossi, Antoniali, Yu, Akhtar, Kaplan, Kelley, Tell, Pucillo: "Endonuclease and redox activities of human apurinic/apyrimidinic endonuclease 1 have distinctive and essential functions in IgA class switch recombination." in: The Journal of biological chemistry, Vol. 294, Issue 13, pp. 5198-5207, (2019) (PubMed).

Cho, Jin, Pang, Wang, Mivechi, Moskophidis et al.: "The Molecular Chaperone Heat Shock Protein 70 Controls Liver Cancer Initiation and Progression by Regulating Adaptive DNA Damage and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated ..." in: Molecular and cellular biology, Vol. 39, Issue 9, (2019) (PubMed).

Pascut, Sukowati, Antoniali, Mangiapane, Burra, Mascaretti, Buonocore, Crocè, Tiribelli, Tell: "Serum AP-endonuclease 1 (sAPE1) as novel biomarker for hepatocellular carcinoma." in: Oncotarget, Vol. 10, Issue 3, pp. 383-394, (2019) (PubMed).

George, Bessho, Bessho: "Inactivation of XPF Sensitizes Cancer Cells to Gemcitabine." in: Journal of nucleic acids, Vol. 2019, pp. 6357609, (2019) (PubMed).

Malfatti, Gerratana, Dalla, Isola, Damante, Di Loreto, Puglisi, Tell: "APE1 and NPM1 protect cancer cells from platinum compounds cytotoxicity and their expression pattern has a prognostic value in TNBC." in: Journal of experimental & clinical cancer research : CR, Vol. 38, Issue 1, pp. 309, (2019) (PubMed).

Sun, Feng, Zhang, Xu: "The endonuclease APE1 processes miR-92b formation, thereby regulating expression of the tumor suppressor LDLR in cervical cancer cells." in: Therapeutic advances in medical oncology, Vol. 11, pp. 1758835919855859, (2019) (PubMed).

Lee, Joo, Lee, Cho, Choi, Kim, Jeon: "ATP Binding Cassette Transporter A1 is Involved in Extracellular Secretion of Acetylated APE1/Ref-1." in: International journal of molecular sciences, Vol. 20, Issue 13, (2019) (PubMed).

Cho, Kumari, Thakur, Vu, Kim, Choi: "Decreased APE-1 by Nitroxoline Enhances Therapeutic Effect in a Temozolomide-resistant Glioblastoma: Correlation with Diffusion Weighted Imaging." in: Scientific reports, Vol. 9, Issue 1, pp. 16613, (2019) (PubMed).

Aliases for APEX1 抗体

apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1) 抗体
APEX nuclease (multifunctional DNA repair enzyme) 1 (apex1) 抗体
APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog (apex1.L) 抗体
DNA-(apurinic or apyrimidinic site) lyase (CNG03640) 抗体
DNA-(apurinic or apyrimidinic site) lyase (CNH01280) 抗体
DNA-(apurinic or apyrimidinic site) lyase (nth) 抗体
DNA-(apurinic or apyrimidinic site) lyase (Spirs_4119) 抗体
DNA-(apurinic or apyrimidinic site) lyase (Palpr_0103) 抗体
apurinic/apyrimidinic endodeoxyribonuclease 1 (Apex1) 抗体
apurinic/apyrimidinic endonuclease 1 (Apex1) 抗体
APE 抗体
APE1 抗体
APEN 抗体
APEX 抗体
Apex 抗体
apex1 抗体
apex1a 抗体
APX 抗体
BAP1 抗体
HAP1 抗体
hm:zehn1532 抗体
MGC76280 抗体
MGC78928 抗体
MGC79645 抗体
REF-1 抗体
Ref-1 抗体
REF1 抗体
wu:fc13d11 抗体
zgc:66204 抗体
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