DNA Damage Repair

DNA是合成任意生物的基因信息的载体。DNA中修复的基因编码对于亚细胞放大可见的过程和生物总体功能至关重要。尽管如此,DNA一直受到内来源的损伤,比如:水解、氧化、烷基化或复制错误。另外,电离辐射、紫外线辐射和过多的化学试剂已经成为威胁DNA完整性的外部因素。

与RNA和蛋白不一样的是,DNA受损后不能降解重新合成。而是存在多种修复途径来确保DNA仍然保持完好。在1974年,弗朗西斯·克里克注意到“在DNA修复中,我们完全漏掉了酶可能的作用。我后来意识到DNA很珍贵,因此有可能存在多种不同的机制。

到今天这个预言还是适用:参与到DNA修复途径复杂的网络中后,一百多个基因被表征。DNA损伤可以通过六种不同的途径修复,这取决于损伤的类型:化学改性、未合并的核苷酸,通过直接反转(DR)、错配修复(MMR)和核苷酸切除修复机制反转交联。DNA单链断裂通过基本切除修复改善。高诱变DNA双链断裂最后通过多种复杂的途径修复,这些途径依赖于姐妹染色单体(在细胞周期S或G2阶段)的同源重组(HR)或双链断裂两端的非同源末端接合(NHEJ)。在DNA损伤不能及时修复的情况下,专门的DNA聚合酶启动跨损伤合成(TLS),从而防止DNA复制叉停止。造成这些修复途径的组件不工作的突变会导致疾病,比如:着色性干皮病、共济失调毛细血管扩张、范科尼贫血和患癌症的倾向。

另外,对于目前通常利用细胞DNA修复机制的靶向基因组编辑方法来说,这些修复机制受到高度关注。

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Canonical Non-Homologous End-Joining

PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide):

This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010].   更多...

XRCC6 - X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6

XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining)):

此分类里的别的抗原:
ATM (Ataxia Telangiectasia Mutated): ATM 抗体 ATM ELISA试剂盒 ATM 蛋白
TRIM29 (Tripartite Motif Containing 29): TRIM29 抗体 TRIM29 ELISA试剂盒 TRIM29 蛋白
ATR (Ataxia Telangiectasia and Rad3 Related): ATR 抗体 ATR ELISA试剂盒  
H2AFX - H2A Histone Family, Member X: H2AFX 抗体 H2AFX ELISA试剂盒 H2AFX 蛋白
XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4): XRCC4 抗体 XRCC4 ELISA试剂盒 XRCC4 蛋白
LIG4 - Ligase IV, DNA, ATP-Dependent: LIG4 抗体 LIG4 ELISA试剂盒 LIG4 蛋白
NHEJ1 - Nonhomologous End-Joining Factor 1: NHEJ1 抗体 NHEJ1 ELISA试剂盒 NHEJ1 蛋白
APTX - Aprataxin: APTX 抗体 APTX ELISA试剂盒 APTX 蛋白
APLF (Aprataxin and PNKP Like Factor): APLF 抗体 APLF ELISA试剂盒 APLF 蛋白
DCLRE1C (DNA Cross-Link Repair 1C): DCLRE1C 抗体 DCLRE1C ELISA试剂盒 DCLRE1C 蛋白
PNKP (Polynucleotide Kinase 3'-Phosphatase): PNKP 抗体 PNKP ELISA试剂盒 PNKP 蛋白
DNTT - Deoxynucleotidyltransferase, terminal: DNTT 抗体 DNTT ELISA试剂盒 DNTT 蛋白
POLL (Polymerase (DNA Directed), lambda): POLL 抗体 POLL ELISA试剂盒 POLL 蛋白
POLM - Polymerase (DNA Directed), mu: POLM 抗体   POLM 蛋白
MRE11A - MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae): MRE11A 抗体 MRE11A ELISA试剂盒 MRE11A 蛋白
RAD50 (RAD50 Homolog (S. Cerevisiae)): RAD50 抗体 RAD50 ELISA试剂盒 RAD50 蛋白
NBN - Nibrin: NBN 抗体 NBN ELISA试剂盒 NBN 蛋白
TP53BP1 (Tumor Protein P53 Binding Protein 1): TP53BP1 抗体 TP53BP1 ELISA试剂盒 TP53BP1 蛋白

Microhomology-Mediated End-Joining

PARP1 (Poly (ADP-Ribose) Polymerase 1):

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery...   更多...
此分类里的别的抗原:
LIG3 (Ligase III, DNA, ATP-Dependent): LIG3 抗体 LIG3 ELISA试剂盒 LIG3 蛋白
LIG2 - Ligase II, DNA, ATP-Dependent:   LIG2 ELISA试剂盒  
PARP2 - Poly (ADP-Ribose) Polymerase 2: PARP2 抗体 PARP2 ELISA试剂盒 PARP2 蛋白
LIG1 (Ligase I, DNA, ATP-Dependent): LIG1 抗体 LIG1 ELISA试剂盒 LIG1 蛋白
ATM (Ataxia Telangiectasia Mutated): ATM 抗体 ATM ELISA试剂盒 ATM 蛋白
TRIM29 (Tripartite Motif Containing 29): TRIM29 抗体 TRIM29 ELISA试剂盒 TRIM29 蛋白
ATR (Ataxia Telangiectasia and Rad3 Related): ATR 抗体 ATR ELISA试剂盒  
RBBP8 - Retinoblastoma Binding Protein 8: RBBP8 抗体 RBBP8 ELISA试剂盒 RBBP8 蛋白
MRE11A - MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae): MRE11A 抗体 MRE11A ELISA试剂盒 MRE11A 蛋白
RAD50 (RAD50 Homolog (S. Cerevisiae)): RAD50 抗体 RAD50 ELISA试剂盒 RAD50 蛋白
NBN - Nibrin: NBN 抗体 NBN ELISA试剂盒 NBN 蛋白
RECQL2 - RECQL2 (ARABIDOPSIS RECQ HELICASE L2), 3'-5' DNA Helicase/ ATP-Dependent Helicase/ Four-Way Junction Helicase/ Protein Binding: RECQL2 抗体 RECQL2 ELISA试剂盒  

Homologous Recombination

RAD51 (DNA Repair Protein Homolog 1):

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of...   更多...

BRCA1 (Breast Cancer 1):

BRCA2 (Breast Cancer 2, Early Onset):

此分类里的别的抗原:
POLE (Polymerase (DNA Directed), Epsilon, Catalytic Subunit): POLE 抗体    
POLE2 - Polymerase (DNA Directed), epsilon 2 (p59 Subunit): POLE2 抗体 POLE2 ELISA试剂盒 POLE2 蛋白
POLE3 - Polymerase (DNA Directed), epsilon 3 (p17 Subunit): POLE3 抗体 POLE3 ELISA试剂盒 POLE3 蛋白
POLE4 (Polymerase (DNA-Directed), epsilon 4 (p12 Subunit)): POLE4 抗体 POLE4 ELISA试剂盒 POLE4 蛋白
POLD1 - Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa: POLD1 抗体 POLD1 ELISA试剂盒 POLD1 蛋白
POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit): POLD2 抗体 POLD2 ELISA试剂盒 POLD2 蛋白
POLD3 - Polymerase (DNA-Directed), delta 3, Accessory Subunit: POLD3 抗体 POLD3 ELISA试剂盒 POLD3 蛋白
POLD4 (Polymerase (DNA-Directed), delta 4, Accessory Subunit): POLD4 抗体 POLD4 ELISA试剂盒 POLD4 蛋白
ATM (Ataxia Telangiectasia Mutated): ATM 抗体 ATM ELISA试剂盒 ATM 蛋白
TRIM29 (Tripartite Motif Containing 29): TRIM29 抗体 TRIM29 ELISA试剂盒 TRIM29 蛋白
ATR (Ataxia Telangiectasia and Rad3 Related): ATR 抗体 ATR ELISA试剂盒  
Rad51B - RAD51 Homolog B (S. Cerevisiae): Rad51B 抗体   Rad51B 蛋白
RAD51C (RAD51 Homolog C (S. Cerevisiae)): RAD51C 抗体 RAD51C ELISA试剂盒 RAD51C 蛋白
XRCC2 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 2): XRCC2 抗体 XRCC2 ELISA试剂盒 XRCC2 蛋白
XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3): XRCC3 抗体 XRCC3 ELISA试剂盒 XRCC3 蛋白
BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1): BRIP1 抗体 BRIP1 ELISA试剂盒  
BARD1 (BRCA1 Associated RING Domain 1): BARD1 抗体 BARD1 ELISA试剂盒 BARD1 蛋白
RBBP8 - Retinoblastoma Binding Protein 8: RBBP8 抗体 RBBP8 ELISA试剂盒 RBBP8 蛋白
FAM175A - Family with Sequence Similarity 175, Member A: FAM175A 抗体 FAM175A ELISA试剂盒 FAM175A 蛋白
UIMC1 - Ubiquitin Interaction Motif Containing 1: UIMC1 抗体 UIMC1 ELISA试剂盒 UIMC1 蛋白
MRE11A - MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae): MRE11A 抗体 MRE11A ELISA试剂盒 MRE11A 蛋白
RAD50 (RAD50 Homolog (S. Cerevisiae)): RAD50 抗体 RAD50 ELISA试剂盒 RAD50 蛋白
NBN - Nibrin: NBN 抗体 NBN ELISA试剂盒 NBN 蛋白
TP53BP1 (Tumor Protein P53 Binding Protein 1): TP53BP1 抗体 TP53BP1 ELISA试剂盒 TP53BP1 蛋白
RPA1 - Replication Protein A1, 70kDa: RPA1 抗体 RPA1 ELISA试剂盒 RPA1 蛋白
RPA2 (Replication Protein A2, 32kDa): RPA2 抗体 RPA2 ELISA试剂盒 RPA2 蛋白
RPA3 (Replication Protein A3, 14kDa): RPA3 抗体   RPA3 蛋白
PALB2 (Partner and Localizer of BRCA2): PALB2 抗体 PALB2 ELISA试剂盒 PALB2 蛋白
TOP3A (Topoisomerase (DNA) III alpha): TOP3A 抗体 TOP3A ELISA试剂盒  
RMI1 (Homolog of Yeast RecQ-mediated Genome Instability 1): RMI1 抗体 RMI1 ELISA试剂盒 RMI1 蛋白
RMI2 (RMI2, RecQ Mediated Genome Instability 2, Homolog (S. Cerevisiae)): RMI2 抗体 RMI2 ELISA试剂盒 RMI2 蛋白
DNA2 (DNA Replication Helicase 2 Homolog (Yeast)): DNA2 抗体 DNA2 ELISA试剂盒  
RECQL2 - RECQL2 (ARABIDOPSIS RECQ HELICASE L2), 3'-5' DNA Helicase/ ATP-Dependent Helicase/ Four-Way Junction Helicase/ Protein Binding: RECQL2 抗体 RECQL2 ELISA试剂盒  
RAD54L (RAD54-Like (S. Cerevisiae)): RAD54L 抗体 RAD54L ELISA试剂盒 RAD54L 蛋白
MUS81 (MUS81 Endonuclease Homolog (S. Cerevisiae)): MUS81 抗体 MUS81 ELISA试剂盒 MUS81 蛋白
SLX1B - SLX1 Structure-Specific Endonuclease Subunit Homolog B (S. Cerevisiae): SLX1B 抗体 SLX1B ELISA试剂盒 SLX1B 蛋白
BTBD12 - BTB (POZ) Domain Containing 12: BTBD12 抗体 BTBD12 ELISA试剂盒  
GEN1 (Gen Endonuclease Homolog 1 (Drosophila)): GEN1 抗体    

Single Strand Annealing

MSH2 - MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli)

ERCC1 (Excision Repair Cross Complementing Polypeptide-1):

此分类里的别的抗原:
MSH3 (MutS Homolog 3 (E. Coli)): MSH3 抗体 MSH3 ELISA试剂盒  
ERCC4 - Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4: ERCC4 抗体 ERCC4 ELISA试剂盒  
ATM (Ataxia Telangiectasia Mutated): ATM 抗体 ATM ELISA试剂盒 ATM 蛋白
TRIM29 (Tripartite Motif Containing 29): TRIM29 抗体 TRIM29 ELISA试剂盒 TRIM29 蛋白
ATR (Ataxia Telangiectasia and Rad3 Related): ATR 抗体 ATR ELISA试剂盒  
MRE11A - MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae): MRE11A 抗体 MRE11A ELISA试剂盒 MRE11A 蛋白
RAD50 (RAD50 Homolog (S. Cerevisiae)): RAD50 抗体 RAD50 ELISA试剂盒 RAD50 蛋白
NBN - Nibrin: NBN 抗体 NBN ELISA试剂盒 NBN 蛋白
RPA1 - Replication Protein A1, 70kDa: RPA1 抗体 RPA1 ELISA试剂盒 RPA1 蛋白
RPA2 (Replication Protein A2, 32kDa): RPA2 抗体 RPA2 ELISA试剂盒 RPA2 蛋白
RPA3 (Replication Protein A3, 14kDa): RPA3 抗体   RPA3 蛋白
RAD52 (RAD52 Homolog (S. Cerevisiae)): RAD52 抗体 RAD52 ELISA试剂盒 RAD52 蛋白

Break-Induced Replication

MCM2 - Minichromosome Maintenance Complex Component 2

MCM7 - Minichromosome Maintenance Complex Component 7

此分类里的别的抗原:
RAD51 (DNA Repair Protein Homolog 1): RAD51 抗体 RAD51 ELISA试剂盒 RAD51 蛋白
MRE11A - MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae): MRE11A 抗体 MRE11A ELISA试剂盒 MRE11A 蛋白
RAD50 (RAD50 Homolog (S. Cerevisiae)): RAD50 抗体 RAD50 ELISA试剂盒 RAD50 蛋白
NBN - Nibrin: NBN 抗体 NBN ELISA试剂盒 NBN 蛋白
RPA1 - Replication Protein A1, 70kDa: RPA1 抗体 RPA1 ELISA试剂盒 RPA1 蛋白
RPA2 (Replication Protein A2, 32kDa): RPA2 抗体 RPA2 ELISA试剂盒 RPA2 蛋白
RPA3 (Replication Protein A3, 14kDa): RPA3 抗体   RPA3 蛋白
MCM3 (Minichromosome Maintenance Complex Component 3): MCM3 抗体 MCM3 ELISA试剂盒 MCM3 蛋白
MCM4 (Minichromosome Maintenance Deficient 4): MCM4 抗体 MCM4 ELISA试剂盒 MCM4 蛋白
MCM5 - Minichromosome Maintenance Complex Component 5: MCM5 抗体 MCM5 ELISA试剂盒 MCM5 蛋白
MCM6 - Minichromosome Maintenance Complex Component 6: MCM6 抗体 MCM6 ELISA试剂盒 MCM6 蛋白

Base Excision Repair

OGG1 (8-Oxoguanine DNA Glycosylase):

This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the...   更多...

UNG (Uracil-DNA Glycosylase):

APEX1 - APEX Nuclease (Multifunctional DNA Repair Enzyme) 1

此分类里的别的抗原:
MPG - N-Methylpurine-DNA Glycosylase: MPG 抗体 MPG ELISA试剂盒 MPG 蛋白
SMUG1 - Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1: SMUG1 抗体 SMUG1 ELISA试剂盒 SMUG1 蛋白
TDG - Thymine-DNA Glycosylase: TDG 抗体 TDG ELISA试剂盒 TDG 蛋白
MBD4 (Methyl-CpG Binding Domain Protein 4): MBD4 抗体 MBD4 ELISA试剂盒 MBD4 蛋白
MUTYH - MutY Homolog (E. Coli): MUTYH 抗体 MUTYH ELISA试剂盒 MUTYH 蛋白
NEIL1 (Endonuclease VIII-Like 1): NEIL1 抗体 NEIL1 ELISA试剂盒 NEIL1 蛋白
NEIL2 (Nei Endonuclease VIII-Like 2 (E. Coli)): NEIL2 抗体 NEIL2 ELISA试剂盒 NEIL2 蛋白
NEIL3 (Nei Endonuclease VIII-Like 3 (E. Coli)): NEIL3 抗体 NEIL3 ELISA试剂盒 NEIL3 蛋白
POLB (Polymerase (DNA Directed), beta): POLB 抗体 POLB ELISA试剂盒 POLB 蛋白
POLD1 - Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa: POLD1 抗体 POLD1 ELISA试剂盒 POLD1 蛋白
POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit): POLD2 抗体 POLD2 ELISA试剂盒 POLD2 蛋白
POLD3 - Polymerase (DNA-Directed), delta 3, Accessory Subunit: POLD3 抗体 POLD3 ELISA试剂盒 POLD3 蛋白
POLD4 (Polymerase (DNA-Directed), delta 4, Accessory Subunit): POLD4 抗体 POLD4 ELISA试剂盒 POLD4 蛋白
FEN1 (Flap Structure-Specific Endonuclease 1): FEN1 抗体 FEN1 ELISA试剂盒 FEN1 蛋白
LIG1 (Ligase I, DNA, ATP-Dependent): LIG1 抗体 LIG1 ELISA试剂盒 LIG1 蛋白

Nuleotide Excision Repair

POLR2B - Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa

This gene encodes the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA. [provided by RefSeq, Jul 2008].   更多...

XPC (Xeroderma Pigmentosum, Complementation Group C):

DDB1 (Damage Specific DNA Binding Protein 1):

此分类里的别的抗原:
XPA (Xeroderma Pigmentosum, Complementation Group A): XPA 抗体 XPA ELISA试剂盒 XPA 蛋白
RAD23A (RAD23 Homolog A (S. Cerevisiae)): RAD23A 抗体 RAD23A ELISA试剂盒 RAD23A 蛋白
RAD23B - RAD23 Homolog B (S. Cerevisiae): RAD23B 抗体 RAD23B ELISA试剂盒 RAD23B 蛋白
CETN2 (Centrin, EF-Hand Protein, 2): CETN2 抗体 CETN2 ELISA试剂盒 CETN2 蛋白
DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa): DDB2 抗体 DDB2 ELISA试剂盒 DDB2 蛋白
ERCC1 (Excision Repair Cross Complementing Polypeptide-1): ERCC1 抗体 ERCC1 ELISA试剂盒 ERCC1 蛋白
ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2): ERCC2 抗体 ERCC2 ELISA试剂盒 ERCC2 蛋白
ERCC3 - DNA Repair Protein Complementing XP-B Cells: ERCC3 抗体 ERCC3 ELISA试剂盒 ERCC3 蛋白
GTF2H1 - General Transcription Factor IIH, Polypeptide 1, 62kDa: GTF2H1 抗体 GTF2H1 ELISA试剂盒 GTF2H1 蛋白
GTF2H4 (General Transcription Factor IIH, Polypeptide 4, 52kDa): GTF2H4 抗体   GTF2H4 蛋白
GTF2H3 (General Transcription Factor IIH, Polypeptide 3, 34kD): GTF2H3 抗体 GTF2H3 ELISA试剂盒 GTF2H3 蛋白
GTF2H5 - General Transcription Factor IIH, Polypeptide 5: GTF2H5 抗体 GTF2H5 ELISA试剂盒 GTF2H5 蛋白
CDK7 (Cyclin-Dependent Kinase 7): CDK7 抗体 CDK7 ELISA试剂盒 CDK7 蛋白
RFC1 - Replication Factor C (Activator 1) 1, 145kDa: RFC1 抗体 RFC1 ELISA试剂盒 RFC1 蛋白
RFC2 (Replication Factor C (Activator 1) 2, 40kDa): RFC2 抗体 RFC2 ELISA试剂盒 RFC2 蛋白
RFC3 - Replication Factor C (Activator 1) 3, 38kDa: RFC3 抗体 RFC3 ELISA试剂盒 RFC3 蛋白
RFC4 (Replication Factor C (Activator 1) 4, 37kDa): RFC4 抗体 RFC4 ELISA试剂盒 RFC4 蛋白
RFC5 (Replication Factor C (Activator 1) 5, 36.5kDa): RFC5 抗体 RFC5 ELISA试剂盒 RFC5 蛋白
POLK - Polymerase (DNA Directed) kappa: POLK 抗体 POLK ELISA试剂盒 POLK 蛋白
ERCC4 - Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4: ERCC4 抗体 ERCC4 ELISA试剂盒  
ERCC5 - DNA Repair Protein Complementing XP-G Cells: ERCC5 抗体 ERCC5 ELISA试剂盒 ERCC5 蛋白
ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6): ERCC6 抗体   ERCC6 蛋白
ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8): ERCC8 抗体 ERCC8 ELISA试剂盒 ERCC8 蛋白
POLE (Polymerase (DNA Directed), Epsilon, Catalytic Subunit): POLE 抗体    
POLE2 - Polymerase (DNA Directed), epsilon 2 (p59 Subunit): POLE2 抗体 POLE2 ELISA试剂盒 POLE2 蛋白
POLE3 - Polymerase (DNA Directed), epsilon 3 (p17 Subunit): POLE3 抗体 POLE3 ELISA试剂盒 POLE3 蛋白
POLE4 (Polymerase (DNA-Directed), epsilon 4 (p12 Subunit)): POLE4 抗体 POLE4 ELISA试剂盒 POLE4 蛋白
PCNA (Proliferating Cell Nuclear Antigen): PCNA 抗体 PCNA ELISA试剂盒 PCNA 蛋白
XRCC1 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1): XRCC1 抗体 XRCC1 ELISA试剂盒 XRCC1 蛋白
FEN1 (Flap Structure-Specific Endonuclease 1): FEN1 抗体 FEN1 ELISA试剂盒 FEN1 蛋白
LIG1 (Ligase I, DNA, ATP-Dependent): LIG1 抗体 LIG1 ELISA试剂盒 LIG1 蛋白
RPA1 - Replication Protein A1, 70kDa: RPA1 抗体 RPA1 ELISA试剂盒 RPA1 蛋白
RPA2 (Replication Protein A2, 32kDa): RPA2 抗体 RPA2 ELISA试剂盒 RPA2 蛋白
RPA3 (Replication Protein A3, 14kDa): RPA3 抗体   RPA3 蛋白

Mismatch Repair

MSH2 - MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli)

This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].   更多...

MSH3 (MutS Homolog 3 (E. Coli)):

MSH6 (MutS Homolog 6 (E. Coli)):

此分类里的别的抗原:
MLH1 (MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli)): MLH1 抗体 MLH1 ELISA试剂盒 MLH1 蛋白
PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae)): PMS2 抗体 PMS2 ELISA试剂盒 PMS2 蛋白
RFC1 - Replication Factor C (Activator 1) 1, 145kDa: RFC1 抗体 RFC1 ELISA试剂盒 RFC1 蛋白
RFC2 (Replication Factor C (Activator 1) 2, 40kDa): RFC2 抗体 RFC2 ELISA试剂盒 RFC2 蛋白
RFC3 - Replication Factor C (Activator 1) 3, 38kDa: RFC3 抗体 RFC3 ELISA试剂盒 RFC3 蛋白
RFC4 (Replication Factor C (Activator 1) 4, 37kDa): RFC4 抗体 RFC4 ELISA试剂盒 RFC4 蛋白
RFC5 (Replication Factor C (Activator 1) 5, 36.5kDa): RFC5 抗体 RFC5 ELISA试剂盒 RFC5 蛋白
POLD1 - Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa: POLD1 抗体 POLD1 ELISA试剂盒 POLD1 蛋白
POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit): POLD2 抗体 POLD2 ELISA试剂盒 POLD2 蛋白
POLD3 - Polymerase (DNA-Directed), delta 3, Accessory Subunit: POLD3 抗体 POLD3 ELISA试剂盒 POLD3 蛋白
PCNA (Proliferating Cell Nuclear Antigen): PCNA 抗体 PCNA ELISA试剂盒 PCNA 蛋白
LIG1 (Ligase I, DNA, ATP-Dependent): LIG1 抗体 LIG1 ELISA试剂盒 LIG1 蛋白
RPA1 - Replication Protein A1, 70kDa: RPA1 抗体 RPA1 ELISA试剂盒 RPA1 蛋白
RPA2 (Replication Protein A2, 32kDa): RPA2 抗体 RPA2 ELISA试剂盒 RPA2 蛋白
RPA3 (Replication Protein A3, 14kDa): RPA3 抗体   RPA3 蛋白
EXO1 - Exonuclease 1: EXO1 抗体 EXO1 ELISA试剂盒 EXO1 蛋白

Direct Reversal

MGMT (O6-Methylguanine-DNA-Methyltransferase):

Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a   更多...

ALKBH - AlkB, Alkylation Repair Homolog 1 (E. Coli)

ALKBH2 - AlkB, Alkylation Repair Homolog 2

此分类里的别的抗原:
ALKBH3 - AlkB, Alkylation Repair Homolog 3 (E. Coli): ALKBH3 抗体 ALKBH3 ELISA试剂盒 ALKBH3 蛋白

Trans-Lesion Synthesis

POLI - Polymerase (DNA Directed) iota

POLH - Polymerase (DNA Directed), eta

此分类里的别的抗原:
REV3L (REV3-Like, Polymerase (DNA Directed), Zeta, Catalytic Subunit): REV3L 抗体    
REV1 (REV1, Polymerase (DNA Directed)): REV1 抗体 REV1 ELISA试剂盒 REV1 蛋白
POLK - Polymerase (DNA Directed) kappa: POLK 抗体 POLK ELISA试剂盒 POLK 蛋白
PCNA (Proliferating Cell Nuclear Antigen): PCNA 抗体 PCNA ELISA试剂盒 PCNA 蛋白