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Lipopolysaccharide/tumor necrosis factor-alpha (显示 TNF ELISA试剂盒) treatment increased the expression of iNOS (显示 NOS2 ELISA试剂盒), arginase II (显示 ARG2 ELISA试剂盒), CAT-1, and CAT-2 (显示 SLC7A2 ELISA试剂盒) mRNA.
Estradiol increases arginine transport and CAT-1 (显示 CRAT ELISA试剂盒) activity through modulation of constitutive signaling transduction pathways involving ERK (显示 EPHB2 ELISA试剂盒). Progesterone inhibits arginine transport and CAT-1 (显示 CRAT ELISA试剂盒) via both PKCalpha (显示 PKCa ELISA试剂盒) and ERK1/2 (显示 MAPK1/3 ELISA试剂盒) phosphorylation.
The rs41318021 polymorphism in the SLC7A1 gene was not associated with essential hypertension in 50-year-old subjects.
Overexpression of arginine transporter CAT-1 (显示 CRAT ELISA试剂盒) is associated with accumulation of L-arginine (显示 GATM ELISA试剂盒) and cell growth in human colorectal cancer tissue.
CAT1, CAT2, and CAT3 localized in adult brains but with uneven distribution.
mRNA levels for high-affini (显示 CRAT ELISA试剂盒)ty CAT-1, expressed as a percentage of the wild-type value, are increased by an average 12% an (显示 DMD ELISA试剂盒)d 32% in mdx and transgenic mdx:utr mice respectively.
The data demonstrates that CAT1 (显示 CRAT ELISA试剂盒) significantly (but most likely not exclusively) contributes to the cellular uptake of asymmetric dimethylarginine.
In hypoxic human pulmonary microvascular endothelial cells, overexpression of CAT-1 (显示 CRAT ELISA试剂盒) resulted in significantly greater L-arginine (显示 GATM ELISA试剂盒) transport and NO production
In acute congestive heart failure acute renal impairment function and the modulation of metabolism and extracellular transport by the DDAH-1 (显示 DDAH1 ELISA试剂盒)/CAT-1 (显示 CRAT ELISA试剂盒) system determine high ADMA and SDMA levels after therapy for acute congestive heart failure.
Insulin (显示 INS ELISA试剂盒) increased hCATs-L-arginine (显示 GATM ELISA试剂盒) transport, maximal transport capacity, and hCAT-1 expression. Sp1 (显示 PSG1 ELISA试剂盒) nuclear protein (显示 RDBP ELISA试剂盒) abundance and binding to DNA, and SLC7A1 promoter activity was increased by insulin (显示 INS ELISA试剂盒).
Data show that the CAT-1 (显示 CRAT ELISA试剂盒) isoform plays a role in arginine uptake.
Arginine supplementation enhances small intestinal expression of SLC7A7 (显示 Slc7a7 ELISA试剂盒) and SLC7A1.
Changes in the expression of b(0,+) and CAT-1 in pigs fed on amino acid supplemented versus high proteins diets.
Data show that in minipigs, increased weight and cholesterol resulting from a high-cholesterol diet are correlated with a decrease in the expression of miRNA-122, and that gene expression levels of CAT1 do not differ between groups.
Radiation hybrid mapping data indicate that the porcine SLC7A1 maps to the distal end of the short arm of pig chromosome 11
Study showed that TRPV6 (显示 TRPV6 ELISA试剂盒)-expressing elements seem to be discretely organized in the brain of mouse. TRPV6 (显示 TRPV6 ELISA试剂盒)-immunoreactive arcuate neurons co-express estrogen receptor alpha (显示 ESR1 ELISA试剂盒) and the ion channel protein (显示 TRPC3 ELISA试剂盒) expression in the mediobasal hypothalamus showed correlation with estrous cycle.
TRPV6 (显示 TRPV6 ELISA试剂盒)-/- mice spontaneously developed osteoarthritis at a younger age and had more severe manifestations of OA than wild-type controls. TRPV6 (显示 TRPV6 ELISA试剂盒) could regulate certain chondrocyte functions, including ECM (显示 MMRN1 ELISA试剂盒) secretion, cell proliferation, and apoptosis.
A time-dependent decrease in serum and tissue ADMA and increase in mRNA expression of DDAH-1 and PRMT-1 as well as higher rates of mRNA expression of CAT-1 and lower rates of CAT-2A and CAT-2B were found after 8-week MCD diet.
TRPV6 (显示 TRPV6 ELISA试剂盒) plays an essential role in bone metabolism and is a critical regulator in osteoclasts differentiation and bone resorption.
CAT1 overexpression prevents obesity-induced hypertension by reducing the influence of the SNS (显示 SCN10A ELISA试剂盒) on the maintenance of arterial pressure but not by buffering pressor responses to stress.
Adra2a (显示 ADRA2A ELISA试剂盒) is expressed in the mesenchyme of the mouse stomach primordium at E11.5. Fzd5 and Trpv6 (显示 TRPV6 ELISA试剂盒) are expressed in the epithelial layer of the stomach primordium after E11.5.
Endothelial CAT-1 overexpression can counter the ability of oxidative stress.
focus on TRPV6 (显示 TRPV6 ELISA试剂盒) gene polymorphisms, the start of TRPV6 (显示 TRPV6 ELISA试剂盒) translation at a non-AUG codon and the functions of TRPV6 (显示 TRPV6 ELISA试剂盒) in intestinal Ca(2 (显示 CA2 ELISA试剂盒)+) uptake, sperm maturation, and male fertility.
these data indicate that obesity-induced down-regulation of CAT1 expression and subsequent reduced bioavailability of nitric oxide may contribute to the development of obesity-induced hypertension.
Fibroblasts from two long-lived mice mutants (Snell dwarf (显示 POU1F1 ELISA试剂盒) and PAPP-A (显示 PAPPA ELISA试剂盒) knockout) expressed higher levels of CAT1 (a ATF4 (显示 ATF4 ELISA试剂盒) target gene) during stress, suggesting a connection to longevity.
acts as a cationic amino acid transporter and as an ecotropic retrovirus receptor\; plays a role in the Na+-independent y+ cationic amino acid transport system
high affinity cationic amino acid transporter 1
, cationic amino acid transporter 1
, solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
, solute carrier family 7 member 1
, system Y+ basic amino acid transporter
, high affinity cationic amino acid transporter 1-like
, amino acid transporter, cationic 1
, ecotropic retroviral leukemia receptor homolog
, ecotropic retroviral receptor
, ecotropic retrovirus receptor homolog
, cationic amino acid transporter-1
, ecotropic retroviral leukemia receptor
, ecotropic retrovirus receptor
, Solute carrier family 7 member A1 (amino acid transporter cationic 1)
, cationic amino acid transporter, y+ system
, cationinc amino acid transporter 1
, solute carrier family 7, member 1
, calcium transport protein 1
, epithelial calcium channel 2
, osmosensitive transient receptor potential channel 3
, transient receptor potential cation channel subfamily V member 6