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CSK 抗体

(C-Src tyrosine Kinase (CSK))
Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T- cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK (By similarity).
CSK 抗体  (AA 1-100) CSK 抗体  (AA 1-100) CSK 抗体 (AA 1-100) (ABIN560501)

CSK 适用: 人 WB, ELISA, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3A3 unconjugated

CSK 抗体 CSK 抗体 CSK 抗体 (ABIN1513217)

CSK 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

CSK 抗体  (C-Term) CSK 抗体  (C-Term) CSK 抗体 (C-Term) (ABIN184606)

Verified CSK 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

CSK 抗体 by Grade

Find CSK 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

CSK 抗体 by 适用

Find CSK 抗体 for a variety of species such as anti-Human CSK, anti-Mouse CSK, anti-Rat CSK. The species listed below are among those available. Click on a link to go to the corresponding products.

CSK 抗体 by 应用范围

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CSK 抗体 by 抗体来源

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CSK 抗体 by 抗原表位

Find CSK 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

CSK 抗体 by 克隆形成能力

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CSK 抗体 by 克隆

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CSK 抗体 by 标记

Find CSK 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular CSK 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IP, IHC (p), RNAi
Validations
  • (8)
Cat. No. ABIN560501
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN1513217
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (4)
Cat. No. ABIN184606
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application WB, ELISA, ICC, FACS
Validations
  • (3)
  • (3)
Cat. No. ABIN969069
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN7211357
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7444412
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7174015
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN6243612
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN3184105
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (2)
Cat. No. ABIN1679381
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7265975
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IP, ICC
Validations
  • (2)
Cat. No. ABIN94268
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN3042764
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC (p), IF (p), IF (cc), ICC, FACS, IHC (fro)
Validations
  • (1)
Cat. No. ABIN1714136
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC (p), IF (p), IF (cc), ICC, IHC (fro)
Validations
  • (1)
Cat. No. ABIN1714331
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our CSK 抗体

Trepanier, Lei, Xie, MacDonald: "Group II metabotropic glutamate receptors modify N-methyl-D-aspartate receptors via Src kinase." in: Scientific reports, Vol. 3, pp. 926, (2013) (PubMed).

Gallagher, Rambow, Kumasaka, Champeval, Bellacosa, Delmas, Larue: "Beta-catenin inhibits melanocyte migration but induces melanoma metastasis." in: Oncogene, Vol. 32, Issue 17, pp. 2230-8, (2013) (PubMed).

Levy, Ehret, Rice, Verwoert, Launer, Dehghan, Glazer, Morrison, Johnson, Aspelund, Aulchenko, Lumley, Köttgen, Vasan, Rivadeneira, Eiriksdottir, Guo, Arking, Mitchell, Mattace-Raso, Smith, Taylor et al.: "Genome-wide association study of blood pressure and hypertension. ..." in: Nature genetics, Vol. 41, Issue 6, pp. 677-87, (2010) (PubMed).

Ho, Levy, Rose, Johnson, Ridker, Chasman: "Discovery and replication of novel blood pressure genetic loci in the Women's Genome Health Study." in: Journal of hypertension, Vol. 29, Issue 1, pp. 62-9, (2010) (PubMed).

Kreil, Hochhaus, Cross, Chase: "A high-throughput candidate gene mutation screen in lymphoproliferative and myeloproliferative neoplasias." in: Leukemia research, Vol. 33, Issue 9, pp. e168-9, (2009) (PubMed).

Lin, Lee, Sun: "Functions of the activation loop in Csk protein-tyrosine kinase." in: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 24072-7, (2003) (PubMed).

Huang, Chen, Inoue, Chen: "Tyrosine phosphorylation of I-kappa B kinase alpha/beta by protein kinase C-dependent c-Src activation is involved in TNF-alpha-induced cyclooxygenase-2 expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 9, pp. 4767-75, (2003) (PubMed).

Natarajan, Rajala, Chodosh: "Corneal IL-8 expression following adenovirus infection is mediated by c-Src activation in human corneal fibroblasts." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 12, pp. 6234-43, (2003) (PubMed).

Bénistant, Bourgaux, Chapuis, Mottet, Roche, Bali: "The COOH-terminal Src kinase Csk is a tumor antigen in human carcinoma." in: Cancer research, Vol. 61, Issue 4, pp. 1415-20, (2001) (PubMed).

Takayama, Tanaka, Nagai, Okada et al.: "Adenovirus-mediated overexpression of C-terminal Src kinase (Csk) in type I astrocytes interferes with cell spreading and attachment to fibronectin. Correlation with tyrosine phosphorylations of ..." in: The Journal of biological chemistry, Vol. 274, Issue 4, pp. 2291-7, (1999) (PubMed).

Aliases for CSK 抗体

C-terminal Src kinase (CSK) 抗体
c-src tyrosine kinase (Csk) 抗体
C-terminal Src kinase (Csk) 抗体
c-src tyrosine kinase (CSK) 抗体
CSK, non-receptor tyrosine kinase (CSK) 抗体
AW212630 抗体
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