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F12 ELISA试剂盒

(Coagulation Factor XII (F12))
This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged. [provided by RefSeq, Jul 2008].
F12 ELISA 试剂盒 F12 ELISA 试剂盒 F12 ELISA 试剂盒 (ABIN6954882)

F12 适用: 人 Colorimetric Sandwich ELISA 1.56 ng/mL - 100 ng/mL Plasma

F12 ELISA 试剂盒 F12 ELISA 试剂盒 F12 ELISA 试剂盒 (ABIN6965907)

F12 适用: 人 Colorimetric Sandwich ELISA 3.125 ng/mL - 200 ng/mL Plasma, Serum, Tissue Homogenate

F12 ELISA 试剂盒 F12 ELISA 试剂盒 F12 ELISA 试剂盒 (ABIN6965908)

F12 适用: 小鼠 Colorimetric Sandwich ELISA 3.125 ng/mL - 200 ng/mL Plasma, Serum, Tissue Homogenate

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Popular F12 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
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  • (1)
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Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965907
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
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Cat. No. ABIN6965908
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965909
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN7012892
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
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Cat. No. ABIN6954883
Quantity 96 tests
Datasheet Datasheet
Reactivity Monkey
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1560640
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
Cat. No. ABIN627812
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN626996
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1052202
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method Competition ELISA
Validations
Cat. No. ABIN1052200
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method
Validations
Cat. No. ABIN1126928
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1126925
Quantity 96 tests
Datasheet Datasheet
Reactivity Monkey
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN1052201
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN990257
Quantity 96 tests
Datasheet Datasheet

Latest Publications for our F12 ELISA试剂盒

Teligui, Dalmayrac, Corbeau, Bouquet, Godon, Denommé, Binuani, Verron, Boer, Baufreton: "Ex vivo simulation of cardiopulmonary bypass with human blood for hemocompatibility testing." in: Perfusion, Vol. 31, Issue 5, pp. 376-83, (2016) (PubMed).

Gao, Lu, Xiao, Yang, Chen, Zhou, Wen, Li, Wu, Jiang, Liu, Zhao: "β-Eliminative depolymerization of the fucosylated chondroitin sulfate and anticoagulant activities of resulting fragments." in: Carbohydrate polymers, Vol. 127, pp. 427-37, (2015) (PubMed).

Bhargava, Becker, Viken, Jagtap, Dey, Steinbach, Wu, Kumar, Bitterman, Ingbar, Wendt: "Proteomic profiles in acute respiratory distress syndrome differentiates survivors from non-survivors." in: PLoS ONE, Vol. 9, Issue 10, pp. e109713, (2014) (PubMed).

Stoll, Kleinschnitz, Nieswandt: "Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment." in: Blood, Vol. 112, Issue 9, pp. 3555-62, (2008) (PubMed).

Maas, Govers-Riemslag, Bouma, Schiks, Hazenberg, Lokhorst, Hammarström, ten Cate, de Groot, Bouma, Gebbink: "Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation." in: The Journal of clinical investigation, Vol. 118, Issue 9, pp. 3208-18, (2008) (PubMed).

Schmaier: "The elusive physiologic role of Factor XII." in: The Journal of clinical investigation, Vol. 118, Issue 9, pp. 3006-9, (2008) (PubMed).

Aliases for F12 ELISA试剂盒

coagulation factor XII (F12) ELISA试剂盒
coagulation factor XII (Hageman factor) (F12) ELISA试剂盒
FXII ELISA试剂盒
HAE3 ELISA试剂盒
HAEX ELISA试剂盒
HAF ELISA试剂盒
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