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F12 抗体

(Coagulation Factor XII (F12))
This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged. [provided by RefSeq, Jul 2008].
F12 抗体  (AA 400-615) F12 抗体  (AA 400-615) F12 抗体 (AA 400-615) (ABIN7432373)

F12 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

F12 抗体  (AA 352-587) F12 抗体  (AA 352-587) F12 抗体 (AA 352-587) (ABIN7432376)

F12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

F12 抗体  (AA 191-300) F12 抗体  (AA 191-300) F12 抗体 (AA 191-300) (ABIN560829)

F12 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3A3 unconjugated

F12 抗体 by 适用

Find F12 抗体 for a variety of species such as anti-Human F12, anti-Mouse F12, anti-Rat F12. The species listed below are among those available. Click on a link to go to the corresponding products.

F12 抗体 by 应用范围

Find F12 抗体 validated for a specific application such as WB, ELISA, IHC, IP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

F12 抗体 by 抗体来源

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F12 抗体 by 抗原表位

Find F12 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

F12 抗体 by 克隆形成能力

Find available monoclonal or polyclonal F12 抗体. Click on a link to go to the corresponding products.

F12 抗体 by 克隆

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F12 抗体 by 标记

Find F12 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular F12 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7432373
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7432376
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, PLA
Validations
  • (3)
Cat. No. ABIN560829
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IP, IHC (p), IEP
Validations
  • (3)
Cat. No. ABIN364435
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC, ICC, IF
Validations
  • (3)
Cat. No. ABIN6261640
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN337368
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7186683
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7147997
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN3022402
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IP, IEP
Validations
  • (1)
Cat. No. ABIN458009
Quantity 1 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN7259454
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application WB
Validations
  • (1)
Cat. No. ABIN6741747
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN1853534
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN7303398
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IP, EIA, IHC (p)
Validations
  • (2)
Cat. No. ABIN614924
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our F12 抗体

Labberton, Kenne, Long, Nickel, Di Gennaro, Rigg, Hernandez, Butler, Maas, Stavrou, Renné: "Neutralizing blood-borne polyphosphate in vivo provides safe thromboprotection." in: Nature communications, Vol. 7, pp. 12616, (2018) (PubMed).

Kato, Nicholson, Neiman, Rantalainen, Holmes, Barrett, Uhlén, Nilsson, Spector, Schwenk: "Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model." in: Proteome science, Vol. 9, pp. 73, (2011) (PubMed).

Aliases for F12 抗体

coagulation factor XII (F12) 抗体
coagulation factor XII (Hageman factor) (F12) 抗体
FXII 抗体
HAE3 抗体
HAEX 抗体
HAF 抗体
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