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Complement Factor H (CFH) ELISA试剂盒产品概述

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Complement Factor H ELISA试剂盒 (CFH)
在www.antibodies-online.cn可供56 Complement Factor H (CFH) ELISA试剂盒的14不同的供货商。 再加上,我们可以发Complement Factor H 抗体 (257)Complement Factor H 蛋白 (19)和数多这个蛋白质的别的产品。 总共341 Complement Factor H产品已列进来了。
别名:
AHUS1, AMBP1, ARMD4, ARMS1, CFH, CFHL3, fH, FHL1, HF, HF1, HF2, HUS, im:7147412, Mud-1, NOM, Sas-1, Sas1, si:ch211-207o17.2

引用最多的Complement Factor H ELISA试剂盒

  1. Human Complement Factor H ELISA Kit for Sandwich ELISA - ABIN365061 : Shi, Zhao, Liu, Zhang, Zhou, Pu: Serum proteomics of methamphetamine addicts and up-regulation of complement factor H related to methamphetamine addiction. in Neuroscience letters 2012 (PubMed)
    Show all 2 references for ABIN365061

适于 Complement Factor H 相互作用对的更多 ELISA 试剂盒

Chimpanzee Complement Factor H (CFH) interaction partners

  1. interaction between sialylated Neisseria gonorrhoeae and factor H [factor H]

Zebrafish Complement Factor H (CFH) interaction partners

  1. Results report the molecular cloning and identification of complement factor H and complement factor H-like 1-4 (CFHL1 (显示 CFHR1 ELISA试剂盒)-4) in Danio rerio.

Mouse (Murine) Complement Factor H (CFH) interaction partners

  1. environmental factors can drive retinal disease in these mice when linked to complement deficits impairing immune function. Both groups of mice had similar levels of retinal amyloid beta accumulation. Consequently there is no direct link between this and inflammation in Cfh(-/-) mice.

  2. absence of plasma CfH conferred susceptibility to glomerulonephritis

  3. This new understanding of the complicated interactions of CFH in AMD (显示 AMD1 ELISA试剂盒)-like pathology provides an improved foundation for the development of targeted therapies for AMD (显示 AMD1 ELISA试剂盒)

  4. data suggest that altered interactions of Cfh with MDA-modified proteins may be relevant in explaining the effects of the Cfh variant.

  5. Cfh and Cfhr2 (显示 CFHR2 ELISA试剂盒) genes are expressed in the mouse outer retina. Only Cfh mRNA was detected in the retinal pigment epithelium, but no protein.

  6. A spectrum of complement dysregulation was modeled on the APOE4 age related macular degeneration mouse model by crossing these mice to complement factor H knockout (cfh-/-) mice to test the impact of excess complement activation.

  7. Data indicate that co-deficiency of factor H (FH) and MASP-1/MASP-3 (显示 MASP1 ELISA试剂盒) did not ameliorate either the plasma Complement C3 (显示 C3 ELISA试剂盒) (C3) activation or glomerular C3 accumulation in FH-deficient mice.

  8. A2E accumulation altered retinal microglial complement regulation by decreasing complement factor H (and increasing complement factor B (显示 CFB ELISA试剂盒) expression), favoring increased complement activation and lipofuscin deposition in the outer retina.

  9. The exaggerated humoral immune response in CFH(-/-) mice was normalized in CFH(-/-)C5aR (显示 C5AR1 ELISA试剂盒)(-/-) double knockout mice, highlighting the C5aR (显示 C5AR1 ELISA试剂盒) dependence.

  10. Properdin (显示 CFB ELISA试剂盒) deficiency exacerbated renal injury in mice lacking complement factor H.

Human Complement Factor H (CFH) interaction partners

  1. Our results show that age-related macular degeneration donors carrying the high risk allele for CFH (C) had significantly more mtDNA damage compared with donors having the wild-type genetic profile.

  2. Data suggest that Staphylococcus aureus surface protein SdrE (serine-aspartate repeat protein E (显示 CRISP1 ELISA试剂盒)) functions as a 'clamp (显示 PDZK1 ELISA试剂盒)' to capture C-terminal tail of human CFH (complement factor H) at a specific ligand-binding site/groove via unique close-dock-lock-latch mechanism and thereby sequesters CFH on surface of S. aureus for complement evasion (immune evasion).

  3. The haplotypic coinheritance of potentially functional variants (including missense variants, novel splice sites, and the CFHR3 (显示 CFHR3 ELISA试剂盒)-CFHR1 (显示 CFHR1 ELISA试剂盒) deletion) was described for the four common haplotypes. Expression of the short and long CFH transcripts differed markedly between the retina and liver.

  4. Data suggest that complement factor H (CFH) attaches to surface of host cells to inhibit complement activation and amplification, preventing destruction of the host cells; SdrE (serine-aspartate repeat protein) of Staphylococcus aureus binds to CFH allowing S. aureus to mimic a host cell and reducing bacterial killing by granulocytes. [Commentary]

  5. Interaction effects between supplement groups and individual complement factor H (CFH) Y402H and age-related maculopathy susceptibility 2 (ARMS2 (显示 ARMS2 ELISA试剂盒)) genotypes, and composite genetic risk groups combining the number of risk alleles for both loci, were evaluated for their association with progression

  6. EMD (显示 EMD ELISA试剂盒) were not AMD (显示 AMD1 ELISA试剂盒)-independently associated with CFH or ARMS2 (显示 ARMS2 ELISA试剂盒) genotypes. Our results indicate that patients without AMD (显示 AMD1 ELISA试剂盒) but with EMD (显示 EMD ELISA试剂盒) can serve as controls in studies evaluating AMD (显示 AMD1 ELISA试剂盒) risk factors.

  7. Despite limited power of this pilot study, our results suggest an association of HF with polymorphisms in ARMS2 (显示 ARMS2 ELISA试剂盒)/HTRA1 (显示 HTRA1 ELISA试剂盒), CFH, APOE4/TOMM40 (显示 TOMM40 ELISA试剂盒), and VEGFA (显示 VEGFA ELISA试剂盒) genes which could be triggered by modification of the extracellular matrix, altered complement system or lipid metabolism.

  8. data suggest that R1210C is a unique C-terminal complement factor H mutation that behaves as a partial complement factor H deficiency, predisposing individuals to diverse pathologies with distinct underlying pathogenic mechanisms; the final disease outcome is then determined by R1210C-independent genetic risk factors

  9. AMD (显示 AMD1 ELISA试剂盒) progression rate is influenced by CFH, and suggest that variants within CFH may have different effects on risk versus progression. However, since CFH:rs10737680 was not significant after Bonferroni correction and explained only a relatively small portion of variation in progression rate beyond that explained by age

  10. We describe a novel CFH/CFHR3 (显示 CFHR3 ELISA试剂盒) hybrid gene secondary to a de novo 6.3-kb deletion that arose through microhomology-mediated end joining rather than nonallelic homologous recombination. We confirmed a transcript from this hybrid gene and showed a secreted protein product that lacks the recognition domain of factor H and exhibits impaired cell surface complement regulation

Pig (Porcine) Complement Factor H (CFH) interaction partners

Complement Factor H (CFH) 抗原简介

Antigen Summary

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with Complement Factor H (CFH)

  • complement factor H (CFH) Elisa Kit
  • complement factor H (cfh) Elisa Kit
  • complement component factor h (Cfh) Elisa Kit
  • complement factor H (Cfh) Elisa Kit
  • AHUS1 Elisa Kit
  • AMBP1 Elisa Kit
  • ARMD4 Elisa Kit
  • ARMS1 Elisa Kit
  • CFH Elisa Kit
  • CFHL3 Elisa Kit
  • fH Elisa Kit
  • FHL1 Elisa Kit
  • HF Elisa Kit
  • HF1 Elisa Kit
  • HF2 Elisa Kit
  • HUS Elisa Kit
  • im:7147412 Elisa Kit
  • Mud-1 Elisa Kit
  • NOM Elisa Kit
  • Sas-1 Elisa Kit
  • Sas1 Elisa Kit
  • si:ch211-207o17.2 Elisa Kit

Protein level used designations for CFH

complement factor H , complement factor H related protein 3A4/5G4 , protein beta-1-H , H factor 1 (complement) , H factor 2 (complement) , adrenomedullin binding protein , age-related maculopathy susceptibility 1 , beta-1-H-globulin , beta-1H , factor H , factor H-like 1 , complement component factor H , complement inhibitory factor H , platelet complement factor H , complement regulator factor H

GENE ID SPECIES
457601 Pan troglodytes
553060 Danio rerio
553297 Danio rerio
100399888 Callithrix jacchus
100451270 Pongo abelii
100465619 Ailuropoda melanoleuca
100600041 Nomascus leucogenys
12628 Mus musculus
3075 Homo sapiens
100051358 Equus caballus
155012 Rattus norvegicus
478952 Canis lupus familiaris
100733902 Cavia porcellus
100340175 Oryctolagus cuniculus
397525 Sus scrofa
280816 Bos taurus
429057 Gallus gallus
100174982 Ovis aries
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