anti-MNT (MNT) 抗体产品概述

Full name:
anti-MNT, MAX Dimerization Protein 抗体 (MNT)
在www.antibodies-online.cn可供25 MNT, MAX Dimerization Protein (MNT) 抗体的9不同的供货商。 再加上,我们可以发MNT 蛋白 (3)和数多这个蛋白质的别的产品。 总共34 MNT产品已列进来了。
别名:
bhlhd3, CT89, HLC-6, HLC4, JIP-4, JIP4, JLP, mad6, MGC98824, mnt, mxd6, PHET, PIG6, rox, xmnt, zgc:165490

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引用最多的anti-MNT 抗体

  1. Cow (Bovine) Polyclonal MNT Primary Antibody for WB - ABIN2781100 : Montagne, Naud, Lavigne: Elucidation of the structural determinants responsible for the specific formation of heterodimeric Mxd1/Max b-HLH-LZ and its binding to E-box sequences. in Journal of molecular biology 2008 (PubMed)

更多抗MNT的相互作用对抗体

Mouse (Murine) MNT, MAX Dimerization Protein (MNT) interaction partners

  1. results redefine the physiological relationship between Mnt and Myc (显示 MYC 抗体) and requirements for Myc (显示 MYC 抗体)-driven oncogenesis

  2. Mxd4 (显示 MXD4 抗体) and Mnt upregulation following OX40 (显示 TNFRSF4 抗体) engagement most likely increases T-cell survival

  3. There is a unique negative regulatory role for Mnt in governing key Myc (显示 MYC 抗体) functions associated with cell proliferation and tumorigenesis.

  4. Mnt may serve a general role as a Myc (显示 MYC 抗体) antagonist.[Review]

  5. Mnt represses Myc (显示 MYC 抗体) target genes and Myc (显示 MYC 抗体) functions as an oncogene (显示 RAB1A 抗体) by relieving Mnt-mediated repression

  6. Loss of protein Mnt in mice results in decreased viability, defective embryonic growth and craniofacial defects.

  7. These results demonstrate that Mnt-Myc (显示 MYC 抗体) antagonism plays a fundamental role in regulating cell cycle entry and proliferation.

  8. Mnt is expressed both in growth-arrested and proliferating mouse fibroblasts and is phosphorylated when resting cells are induced to re-enter the cell cycle

  9. Mnt functions as a tumor suppressor and reveal a critical and surprising role for Mnt in the regulation of T-cell development and in T-cell-dependent immune homeostasis.

  10. The switch from Mnt-Max to Myc (显示 MYC 抗体)-Max during bile duct ligation (cholestasis) and in hepatocytes treated with lithocholic acid is responsible for the induction in p53 (显示 TP53 抗体) and cyclin D1 (显示 CCND1 抗体) expression and contributes to apoptosis.

Human MNT, MAX Dimerization Protein (MNT) interaction partners

  1. In vitro, uremia induced dysregulation of DNA methylation (显示 HELLS 抗体) in differentiating monocytes, which affected several transcription regulators important for monocyte differentiation (e.g., FLT3 (显示 FLT3 抗体), HDAC1 (显示 HDAC1 抗体), MNT) and led to enhanced generation of intermediate monocytes.

  2. Here we review the activities of MYC (显示 MYC 抗体), MNT and other MAX interacting proteins in the setting of T and B cell activation (显示 BLNK 抗体) and oncogenesis

  3. The data demonstrate that the balance between c-Myc (显示 MYC 抗体) and Mnt activity determines the transcriptional outcome of the hTERT promoter by modulation of the chromatin architecture.

  4. The results suggest that MNT, via interaction with Nck1 (显示 NCK1 抗体), inhibits hepatoma cell migration.

  5. downregulation MYCN (显示 MYCN 抗体) was reflected in a decreased MYCN (显示 MYCN 抗体)/Max DNA-binding activity while the Mnt/Max binding did not change during differentiation

  6. Serum stimulation of quiescent cells results in phosphorylation of Mnt and disruption of the critical Mnt-mSin3-HDAC1 (显示 HDAC1 抗体) interaction. This in turn leads to increased expression of the Myc (显示 MYC 抗体)/Mnt target gene cyclin D2 (显示 CCND2 抗体). Review.

  7. Mad1 (显示 MXD1 抗体), Mxi1 (显示 MXI1 抗体) and Rox genes were expressed and displayed mutations in haematological malignancies.

  8. Mxd1 (显示 MXD1 抗体) D112a and Max N78a and H81d, which are located in the leucine zippers of the proteins, can dictate the specificity of heterodimerization and whether or not the Mxd1 (显示 MXD1 抗体)/Max/DNA complex forms.

  9. Missense mutations in Mad1 (显示 MXD1 抗体), Mxi1 (显示 MXI1 抗体) and Rox were found in acute leukemia patients.

  10. The switch from Mnt-Max to Myc (显示 MYC 抗体)-Max during bile duct ligation (cholestasis) and in hepatocytes treated with lithocholic acid is responsible for the induction in p53 (显示 TP53 抗体) and cyclin D1 (显示 CCND1 抗体) expression and contributes to apoptosis.

MNT 抗原简介

Antigen Summary

The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.

Alternative names and synonyms associated with MNT

  • sperm associated antigen 9 (SPAG9) 抗体
  • MNT, MAX dimerization protein (MNT) 抗体
  • max binding protein (Mnt) 抗体
  • MNT, MAX dimerization protein (Mnt) 抗体
  • MAX binding protein (MNT) 抗体
  • MAX binding protein b (mntb) 抗体
  • MNT, MAX dimerization protein (mnt) 抗体
  • max binding protein (CpipJ_CPIJ015473) 抗体
  • MAX binding protein (mnt) 抗体
  • bhlhd3 抗体
  • CT89 抗体
  • HLC-6 抗体
  • HLC4 抗体
  • JIP-4 抗体
  • JIP4 抗体
  • JLP 抗体
  • mad6 抗体
  • MGC98824 抗体
  • mnt 抗体
  • mxd6 抗体
  • PHET 抗体
  • PIG6 抗体
  • rox 抗体
  • xmnt 抗体
  • zgc:165490 抗体

Protein level used designations for MNT

C-Jun-amino-terminal kinase-interacting protein 4 , JNK interacting protein , JNK/SAPK-associated protein , Max-binding protein , c-Jun NH2-terminal kinase-associated leucine zipper protein , cancer/testis antigen 89 , human lung cancer oncogene 6 protein , lung cancer oncogene 4 , mitogen-activated protein kinase 8-interacting protein 4 , proliferation-inducing gene 6 , protein highly expressed in testis , sperm surface protein , sunday driver 1 , MAX binding protein , Max-interacting protein , class D basic helix-loop-helix protein 3 , max-binding protein MNT , myc antagonist MNT , max binding protein , Mnt1

GENE ID SPECIES
9043 Homo sapiens
4335 Homo sapiens
17428 Mus musculus
287521 Rattus norvegicus
427840 Gallus gallus
468141 Pan troglodytes
491202 Canis lupus familiaris
556663 Danio rerio
618576 Bos taurus
734360 Xenopus laevis
6048722 Culex quinquefasciatus
100216033 Xenopus (Silurana) tropicalis
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