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MBD2 蛋白

(Methyl-CpG Binding Domain Protein 2 (MBD2))
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].
MBD2 Protein (AA 1-414) (His tag) MBD2 Protein (AA 1-414) (His tag) MBD2 Protein (AA 1-414) (His tag) (ABIN3120369)

Crystallography grade MBD2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, Crys, ELISA

MBD2 Protein (AA 1-411) (His tag) MBD2 Protein (AA 1-411) (His tag) MBD2 Protein (AA 1-411) (His tag) (ABIN3083393)

Crystallography grade MBD2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, Crys, ELISA

MBD2 Protein (AA 145-411) (His tag) (ABIN7417450)

MBD2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS, WB, Imm, PC

MBD2 蛋白 by Grade

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MBD2 蛋白 by Origin

Find MBD2 蛋白 for a variety of species such as anti-Human MBD2, anti-Mouse MBD2. The species listed below are among those available. Click on a link to go to the corresponding products.

MBD2 蛋白 by Source

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MBD2 蛋白 by 蛋白类型

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MBD2 蛋白 by 应用范围

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Popular MBD2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3120369
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3083393
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417450
Quantity 100 μg
Datasheet Datasheet

Aliases for MBD2 蛋白

methyl-CpG binding domain protein 2 (MBD2) 蛋白
methyl-CpG binding domain protein 2 (Mbd2) 蛋白
methyl-CpG binding domain protein 2 (mbd2) 蛋白
methyl-CpG binding domain protein 2 S homeolog (mbd2.S) 蛋白
DMTase 蛋白
MBD2 蛋白
MBD2a 蛋白
NY-CO-41 蛋白
wu:fa97f06 蛋白
zgc:111862 蛋白
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