anti-K(lysine) Acetyltransferase 2A (KAT2A) 抗体产品概述

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anti-K(lysine) Acetyltransferase 2A 抗体 (KAT2A)
在www.antibodies-online.cn可供109 K(lysine) Acetyltransferase 2A (KAT2A) 抗体的20不同的供货商。 再加上,我们可以发K(lysine) Acetyltransferase 2A 蛋白 (13)和数多这个蛋白质的别的产品。 总共130 K(lysine) Acetyltransferase 2A产品已列进来了。
别名:
1110051E14Rik, AW212720, Gcn5, Gcn5l2, hGCN5, KAT2A, mmGCN5, PCAF-b
列出全部抗体 基因 基因ID UniProt
KAT2A 2648 Q92830
KAT2A 14534 Q9JHD2
KAT2A 303539  

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  1. Human Polyclonal KAT2A Primary Antibody for EIA, WB - ABIN356619 : Kikuchi, Takami, Nakayama: GCN5: a supervisor in all-inclusive control of vertebrate cell cycle progression through transcription regulation of various cell cycle-related genes. in Gene 2005 (PubMed)
    Show all 4 references for 356619

  2. Human Polyclonal KAT2A Primary Antibody for EIA, FACS - ABIN952987 : Kelly, Lerin, Haas, Gygi, Puigserver: GCN5-mediated transcriptional control of the metabolic coactivator PGC-1beta through lysine acetylation. in The Journal of biological chemistry 2009 (PubMed)
    Show all 3 references for 952987

  3. Human Polyclonal KAT2A Primary Antibody for EIA, WB - ABIN952986 : Mao, Gluck, Li, Maine, Li, Zaidi, Repaka, Mayo, Burstein: GCN5 is a required cofactor for a ubiquitin ligase that targets NF-kappaB/RelA. in Genes & development 2009 (PubMed)
    Show all 3 references for 952986

  4. Human Monoclonal KAT2A Primary Antibody for EIA, IF - ABIN487348 : Wiper-Bergeron, Salem, Tomlinson, Wu, Haché: Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPbeta by GCN5. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)
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  5. Human Polyclonal KAT2A Primary Antibody for WB - ABIN387930 : Oishi, Kitagawa, Wada, Takezawa, Tora, Kouzu-Fujita, Takada, Yano, Yanagisawa, Kato: An hGCN5/TRRAP histone acetyltransferase complex co-activates BRCA1 transactivation function through histone modification. in The Journal of biological chemistry 2006 (PubMed)
    Show all 2 references for 387930

  6. Human Polyclonal KAT2A Primary Antibody for ELISA, WB - ABIN1534045 : Yang, Ogryzko, Nishikawa, Howard, Nakatani: A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. in Nature 1996 (PubMed)

更多抗K(lysine) Acetyltransferase 2A的相互作用对抗体

Human K(lysine) Acetyltransferase 2A (KAT2A) interaction partners

  1. Data suggest that expression of GCN5 (histone acetyltransferase GCN5) is induced in skeletal muscle during a 48-hour fast; in contrast, expression of SIRT1 (sirtuin 1 (显示 SIRT1 抗体)) remains unchanged.

  2. Orc5 (显示 ORC5 抗体) associates with the H3 histone (显示 HIST1H3B 抗体) acetyl transferase (显示 HAT1 抗体) GCN5 (also known as KAT2A), and this association enhances the chromatin-opening function of Orc5 (显示 ORC5 抗体).

  3. Methionine was the only essential amino acid that rapidly induced PGC-1alpha acetylation through activating the GCN5 acetyltransferase.

  4. these results may point to the GCN5-NF-kappaB (显示 NFKB1 抗体) pathway as a novel potential molecular target for stem cell mediated regenerative medicine and the treatment of metabolic bone diseases such as osteoporosis.

  5. Acetyltransferase p300 (显示 EP300 抗体) collaborates with chromodomain helicase DNA-binding protein 4 (CHD4 (显示 CHD4 抗体)) to facilitate DNA double-strand break repair

  6. Suggest lysine acetyltransfer as a potential regulator of platelet actin dynamics, and potential roles for lysine acetylation in the molecular coordination of platelet activation and function.

  7. Data uncover GCN5 as a negative regulator of C/EBPalpha (显示 CEBPA 抗体) and demonstrate the importance of C/EBPalpha (显示 CEBPA 抗体) acetylation in myeloid differentiation.

  8. GCN5 Potentiates Glioma Proliferation and Invasion via STAT3 (显示 STAT3 抗体) and AKT (显示 AKT1 抗体) Signaling Pathways

  9. results thus demonstrate that the catalytic activity of GCN5 is stimulated by subunits of the ADA2a (显示 TADA2A 抗体)- or ADA2b (显示 TADA2B 抗体)-containing HAT (显示 MGEA5 抗体) modules and is further increased by incorporation of the distinct HAT (显示 MGEA5 抗体) modules in the ATAC (显示 XCL1 抗体) or SAGA holo-complexes

  10. GCN5 plays a positive role in human colon cancer development, and its suppression holds a great therapeutic potential in antitumor therapy

Mouse (Murine) K(lysine) Acetyltransferase 2A (KAT2A) interaction partners

  1. study reveals previously unknown physiological functions for Gcn5 and a molecular mechanism underlying these functions in regulating T cell immunity; Gcn5 may be an important new target for autoimmune disease therapy

  2. Together, our experiments identify a novel nonhistone substrate of GCN5, highlight an essential role for both GCN5 and RA signaling in early diencephalic development, and elucidate a novel molecular regulatory mechanism for RA signaling that is specific to the developing forebrain.

  3. Methionine was the only essential amino acid that rapidly induced PGC-1alpha acetylation through activating the GCN5 acetyltransferase.

  4. these results may point to the GCN5-NF-kappaB (显示 NFKB1 抗体) pathway as a novel potential molecular target for stem cell mediated regenerative medicine and the treatment of metabolic bone diseases such as osteoporosis.

  5. In addition to reducing atrogene expression, surprisingly inhibiting NF-kappaB (显示 NFKB1 抗体) with IkappaBalpha (显示 NFKBIA 抗体)-SR or by GCN5 knockdown in these muscles also enhanced AKT (显示 AKT1 抗体) and mechanistic target of rapamycin (mTOR (显示 FRAP1 抗体)) activities, which also contributed to the reduction in atrophy.

  6. Gcn5 and PCAF (显示 KAT2B 抗体) repress IFN-beta (显示 IFNB1 抗体) production in an enzymatic activity-independent and non-transcriptional manner: by inhibiting the innate immune signaling kinase TBK1 (显示 TBK1 抗体) in the cytoplasm.

  7. GCN5 and HDAC1 (显示 HDAC1 抗体) are the crucial enzymes that regulating epigenetic reprogramming; we observed dynamic changes in the expression levels of GCN5 and HDAC1 (显示 HDAC1 抗体) during embryo development

  8. In conclusion, these data establish Kat2a as a novel and essential regulator of hippocampal memory consolidation.

  9. Study reveals that Gcn5/PCAF (显示 KAT2B 抗体) facilitate adipogenesis through regulation of PPARgamma (显示 PPARG 抗体) expression and regulate brown adipogenesis by influencing Prdm16 (显示 PRDM16 抗体) expression.

  10. Sirt6 interacts with and modifies GCN5, enhancing GCN5's activity.

K(lysine) Acetyltransferase 2A (KAT2A) 抗原简介

Antigen Summary

KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009

Alternative names and synonyms associated with K(lysine) Acetyltransferase 2A (KAT2A)

  • K(lysine) acetyltransferase 2A (KAT2A) 抗体
  • K(lysine) acetyltransferase 2A (kat2a) 抗体
  • K(lysine) acetyltransferase 2A (Kat2a) 抗体
  • 1110051E14Rik 抗体
  • AW212720 抗体
  • Gcn5 抗体
  • Gcn5l2 抗体
  • hGCN5 抗体
  • KAT2A 抗体
  • mmGCN5 抗体
  • PCAF-b 抗体

Protein level used designations for KAT2A

histone acetyltransferase KAT2A , general control of amino acid synthesis 5-like 2 , GCN5 general control of amino-acid synthesis 5-like 2 , general control of amino acid synthesis protein 5-like 2 , K(lysine) acetyltransferase 2A , GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2 , General control of amino acid synthesis, yeast, homolog-like 2 , STAF97 , histone acetyltransferase GCN5 , hsGCN5 , lysine acetyltransferase 2A , GCN5 general control of amino acid synthesis-like 2 , PCAF-B/GCN5 , general control of amino acid synthesis, yeast homolog-like 2 , general control of amino acid synthesis-like 2

GENE ID SPECIES
552646 Apis mellifera
374232 Gallus gallus
454677 Pan troglodytes
490971 Canis lupus familiaris
100176452 Ciona intestinalis
100597293 Nomascus leucogenys
2648 Homo sapiens
14534 Mus musculus
303539 Rattus norvegicus
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