FABP1 蛋白 (FABP1)产品概述

Full name:
Fatty Acid Binding Protein 1, Liver 蛋白 (FABP1)
在www.antibodies-online.cn可供45 Fatty Acid Binding Protein 1, Liver (FABP1) 蛋白的16不同的供货商。 再加上,我们可以发FABP1 抗体 (196)FABP1 试剂盒 (64)和数多这个蛋白质的别的产品。 总共319 FABP1产品已列进来了。
别名:
FABP, FABP1, Fabpl, Fabplg, L-FABP, LFABP, liver, p14, SCP, SCP.
列出全部蛋白 基因 基因ID UniProt
FABP1 2168 P07148
FABP1 14080 P12710
FABP1 24360 P02692

显示所有的同义词

按照种类FABP1 蛋白 (FABP1)

选择适合您要求的种类

引用最多的FABP1 蛋白

  1. Human FABP1 Protein expressed in Escherichia coli (E. coli) - ABIN666641 : Atshaves, Storey, Huang, Schroeder: Liver fatty acid binding protein expression enhances branched-chain fatty acid metabolism. in Molecular and cellular biochemistry 2004 (PubMed)
    Show all 2 references for 666641

  2. Human FABP1 Protein expressed in Escherichia coli (E. coli) - ABIN2181051 : Gordon, Elshourbagy, Lowe, Liao, Alpers, Taylor: Tissue specific expression and developmental regulation of two genes coding for rat fatty acid binding proteins. in The Journal of biological chemistry 1985 (PubMed)
    Show all 2 references for 2181051

  3. Human FABP1 Protein expressed in Wheat germ - ABIN1353338 : Bronsky, Karpísek, Bronská, Pechová, Jancíková, Kotolová, Stejskal, Prusa, Nevoral: Adiponectin, adipocyte fatty acid binding protein, and epidermal fatty acid binding protein: proteins newly identified in human breast milk. in Clinical chemistry 2006 (PubMed)
    Show all 2 references for 1353338

  4. Human FABP1 Protein expressed in Escherichia coli (E. coli) - ABIN2005183 : Weickert, Loeffelholz, Roden, Chandramouli, Brehm, Nowotny, Osterhoff, Isken, Spranger, Landau, Pfeiffer, Möhlig: A Thr94Ala mutation in human liver fatty acid-binding protein contributes to reduced hepatic glycogenolysis and blunted elevation of plasma glucose levels in lipid-exposed subjects. in American journal of physiology. Endocrinology and metabolism 2007 (PubMed)

更多FABP1互动伙伴

Human Fatty Acid Binding Protein 1, Liver (FABP1) interaction partners

  1. Studies show that despite overall tertiary structure similarity, the hFABP1 differs significantly from rat FABP1 in secondary structure, much larger ligand binding cavity, and affinities/specificities for some ligands. Moreover, while both mouse and hFABP1 mediate ligand induction of PPARA (显示 PPARA 蛋白), they differ markedly in genes induced. hFABP1 T94A variant is associated with altered body mass index.[review]

  2. Urinary L-FABP, NGAL (显示 LCN2 蛋白), Kim-1 (显示 HAVCR1 蛋白) and albumin (显示 ALB 蛋白) levels increased during the acute phase of kidney injury and were significantly correlated with the degree of tubulointerstitial fibrosis during the chronic phase. These markers could detect higher risk of progression to CKD.

  3. L-FABP was found to associate with VEGFR2 on membrane rafts and subsequently activate the Akt/mTOR/P70S6K/4EBP1 and Src/FAK/cdc42 pathways, which resulted in up-regulation of VEGF-A accompanied by an increase in both angiogenic potential and migration activity. L-FABP significantly promoted tumor growth and metastasis in a xenograft mouse model.

  4. In chronic kidney disease, high urinary L-FABP correlated with the development of end-stage renal disease and cardiovascular disease.

  5. In the association of SNPs in FABP1 gene with PCOS, rs2197076 was more closely associated with its main features than rs2241883 and seemed to play a more important role in the pathogenesis of PCOS.

  6. Urinary L-FABP appears to be a sensitive biomarker of acute kidney injury in patients undergoing abdominal aortic repair.

  7. Urinary levels of NGAL (显示 LCN2 蛋白) are more sensitive than uKIM-1 and uL-FABP (显示 FABP2 蛋白) levels in predicting renal scarring in vesicoureteral reflux.

  8. Loss of staining for LFABP appears to be common in hepatocellular carcinoma and may be seen in well-differentiated hepatocellular carcinoma.

  9. In this study, the effects of hepatitis B virus X protein (HBx) mediated FABP1 regulation on hepatic steatosis and the underlying mechanism were determined.

  10. compared with the rs2919872 G allele, the rs2919872 A allele reduces the transcriptional activity of FABP1 promoter, and thereby may link FABP1 gene variation to triglyceride level in humans.

Mouse (Murine) Fatty Acid Binding Protein 1, Liver (FABP1) interaction partners

  1. Lack of a significant decrease in the flux of HDL-[(3)H]CE to biliary FC or bile acids in FABP1(-/-) mice indicates the likely compensation of its function by an as yet unidentified mechanism. Taken together, these studies demonstrate that FABP1 and SCP2 facilitate the preferential movement of HDL-CEs to bile for final elimination

  2. data showed that Fabp1 gene ablation markedly diminished the impact of high-fat diet on brain endocannabinoid levels, especially in male mice

  3. Studies show that despite overall tertiary structure similarity, the hFABP1 differs significantly from rat FABP1 in secondary structure, much larger ligand binding cavity, and affinities/specificities for some ligands. Moreover, while both mouse and hFABP1 mediate ligand induction of PPARA (显示 PPARA 蛋白), they differ markedly in genes induced.

  4. FABP1 knockout increased brain levels of arachidonic acid-containing endocannabinoids

  5. L-FABP was more important in hepatic retention of bile acids, while SCP-2/SCP-x (显示 SCP2 蛋白) more broadly affected biliary bile acid and phospholipid levels.

  6. These findings suggest that some of the phenotypic divergence between the two L-Fabp(-/-) lines may reflect unanticipated differences in genetic background, underscoring the importance of genetic background in phenotypic characterization.

  7. Loss of L-FABP and SCP-2 (显示 CRISP3 蛋白), or both induces hepatic lipid accumulation in female mice and mimics non-alcoholic fatty liver disease.

  8. L-FABP appears to function more in hepatic retention of bile acids as well as hepatic uptake and biliary secretion of HDL (显示 HSD11B1 蛋白)-cholesterol

  9. L-FABP is not required to channel ATGL (显示 PNPLA2 蛋白)-hydrolyzed FAs (显示 FAS 蛋白) to mitochondria for beta-oxidation or the nucleus for PPAR-alpha (显示 PPARA 蛋白) regulation

  10. Data show that combined deletion of microsomal triglyceride transfer protein (Mttp (显示 MTTP 蛋白)) and liver fatty acid binding protein 1 (L-Fabp) are protected from lithogenic diet (LD)-induced gallstone formation.

蛋白简介FABP1

蛋白简介

This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism.

Alternative names and synonyms associated with FABP1

  • fatty acid binding protein 1, liver (FABP1)
  • fatty acid binding protein 1, liver (LOC100354672)
  • fatty acid binding protein 1, liver (Fabp1)
  • liver basic fatty acid binding protein (LBFABP)
  • FABP 蛋白
  • FABP1 蛋白
  • Fabpl 蛋白
  • Fabplg 蛋白
  • L-FABP 蛋白
  • LFABP 蛋白
  • liver 蛋白
  • p14 蛋白
  • SCP 蛋白
  • SCP. 蛋白

Protein level used designations for FABP1

fatty acid binding protein 1, liver , fatty acid-binding protein, liver , fafatty acid binding protein 1, liver , fatty acid-binding protein 1 , liver-type fatty acid-binding protein , 14 kDa selenium-binding protein , fatty acid binding protein liver , Z-protein , squalene- and sterol-carrier protein , fatty acid-binding protein , liver fatty acid binding protein , L-FABP , L-BABP , LB-FABP , liver basic FABP , liver bile acid-binding protein

GENE ID SPECIES
736471 Pan troglodytes
100171896 Pongo abelii
100227345 Taeniopygia guttata
100354672 Oryctolagus cuniculus
2168 Homo sapiens
14080 Mus musculus
24360 Rattus norvegicus
445535 Sus scrofa
374015 Gallus gallus
327700 Bos taurus
403619 Canis lupus familiaris
395345 Gallus gallus
FABP1 蛋白 (FABP1) 精选生产商
您还需要查找其他产品吗?