anti-BRD4 (BRD4) 抗体产品概述

Full name:
anti-Bromodomain Containing 4 抗体 (BRD4)
在www.antibodies-online.cn可供103 Bromodomain Containing 4 (BRD4) 抗体的15不同的供货商。 再加上,我们可以发BRD4 蛋白 (8)BRD4 试剂盒 (5)和数多这个蛋白质的别的产品。 总共122 BRD4产品已列进来了。
别名:
BRD4, brd4-b, Brd5, CAP, fb18g03, HUNK1, HUNKI, MCAP, WI-11513, wu:fb18g03

最受欢迎的抗anti-BRD4 (BRD4) 抗体

选择您的来源和应用

抗Human BRD4 抗体:

抗Mouse (Murine) BRD4 抗体:

抗Rat (Rattus) BRD4 抗体:

所有可销售的anti-BRD4 抗体

您会转到已过滤好的搜索

引用最多的anti-BRD4 抗体

  1. Human Polyclonal BRD4 Primary Antibody for ICC, IF - ABIN438710 : Rahman, Sowa, Ottinger, Smith, Shi, Harper, Howley: The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3. in Molecular and cellular biology 2011 (PubMed)
    Show all 3 references for 438710

  2. Human Polyclonal BRD4 Primary Antibody for ICC, IF - ABIN4285227 : Zuber, Shi, Wang, Rappaport, Herrmann, Sison, Magoon, Qi, Blatt, Wunderlich, Taylor, Johns, Chicas, Mulloy, Kogan, Brown, Valent, Bradner, Lowe, Vakoc: RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. in Nature 2011 (PubMed)
    Show all 2 references for 4285227

  3. Human Polyclonal BRD4 Primary Antibody for ChIP, WB - ABIN2668492 : Flajollet, Rachez, Ploton, Schulz, Gallais, Métivier, Pawlak, Leray, Issulahi, Héliot, Staels, Salbert, Lefebvre: The elongation complex components BRD4 and MLLT3/AF9 are transcriptional coactivators of nuclear retinoid receptors. in PLoS ONE 2013 (PubMed)
    Show all 2 references for 2668492

  4. Cow (Bovine) Polyclonal BRD4 Primary Antibody for ChIP, IF - ABIN2780921 : Schweiger, You, Howley: Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function. in Journal of virology 2006 (PubMed)

更多抗BRD4的相互作用对抗体

Zebrafish Bromodomain Containing 4 (BRD4) interaction partners

  1. Brd4 associates with mitotic chromosomes throughout early zebrafish embryogenesis

Human Bromodomain Containing 4 (BRD4) interaction partners

  1. These findings reveal a novel mechanism by which the HBV genome hijacks the host P-TEFb (显示 CCNT1 抗体)-containing complexes to promote its own transcription; both the super elongation complex and BRD4 can bind to the HBV genome.

  2. Chemical degrader of BET bromodomain proteins, dBET6, led to the unexpected identification of BRD4 as master regulator of global transcription elongation in acute T-cell leukemia. BRD4 loss does not directly affect CDK9 (显示 CDK9 抗体) localization.

  3. BRD4 binds and stays associated with chromatin during mitosis, bookmarking early G1 genes and reactivating transcription after mitotic silencing. BRD4 acts as a passive scaffold via its recruitment of vital transcription factors and as an active kinase that phosphorylates RNA polymerase II. A model in which BRD4 actively coordinates chromatin structure and transcription is described. Review.

  4. we have discovered that BRD4-bound super-enhancers provide a powerful tool for enriching and prioritizing PC and BC genetic risk loci

  5. BRD4 represses autophagy and lysosome gene expression. This repression is alleviated during nutrient deprivation through AMPK (显示 PRKAA1 抗体)-SIRT1 (显示 SIRT1 抗体) signaling, allowing autophagy activation. BRD4 inhibition enhances autophagic flux and lysosomal function and promotes the degradation of protein aggregates. Sakamaki et

  6. The studies show that BRD4 inhibition may have therapeutic implications for the treatment of mitochondrial diseases.

  7. The studies show that BRD4 inhibition may have therapeutic implications for the treatment of mitochondrial diseases.

  8. A BRD4 missense mutation was the likely disease-causing mutation in this family with autosomal dominant syndromic congenital cataracts associated with neuro-skeletal anomalies.

  9. these studies highlight the importance of Brd4 in Helicobacter pylori-induced inflammatory gene expression and suggest that Brd4 could be a potential therapeutic target for the treatment of Helicobacter pylori-triggered inflammatory diseases and cancer

  10. BRD4 positively regulates EZH2 (显示 EZH2 抗体) transcription through upregulation of C-MYC (显示 MYC 抗体), and is a novel promising target for pharmacologic treatment in transcriptional program intervention against this intractable disease.

Mouse (Murine) Bromodomain Containing 4 (BRD4) interaction partners

  1. Fmr1 (显示 FMR1 抗体) knockout (KO) mice show widespread changes in histone marks as well as transcriptional misregulation resulting in increased expression of many critical synaptic genes. Data suggest that one chromatin target of FMRP (显示 FMR1 抗体), the reader protein Brd4, appears to be significantly involved in this transcriptional disruption.

  2. The functional domains of mouse BRD4 and its role in transcription are described. Review.

  3. Brd2 (显示 BRD2 抗体) and Brd4 genetic transcription required for Th17 cell development and adaptive immunity.

  4. These data provide a detailed mechanism for how activated NF-kappaB (显示 NFKB1 抗体) and BRD4 control epithelial-mesenchymal transition initiation and transcriptional elongation in model airway epithelial cells in vitro and in a murine pulmonary fibrosis model in vivo.

  5. DOT1L (显示 DOT1L 抗体), via dimethylated histone H3 (显示 HIST3H3 抗体) K79, facilitates histone H4 (显示 HIST1H4H 抗体) acetylation, which in turn regulates the binding of BRD4 to chromatin in acute lymphoblastic leukemia.

  6. Acute induction of genes related to lipid accumulation in the livers of mice force-fed with fructose is associated with the induction of histone acetylation and BRD4 binding around these genes

  7. Both mouse and human BRD4 have intrinsic histone acetyltransferase (显示 HAT 抗体) activity.

  8. the interaction between BRD4 and Mediator has functional importance for gene-specific transcriptional activation and for acute myeloid leukemia (显示 BCL11A 抗体) maintenance.

  9. our data demonstrate the fundamental role of Brd4 in monitoring cell differentiation through its interaction with acetylated histone marks and disruption of Brd4 may cause aberrant differentiation.

  10. Data show that CCAAT-enhancer-binding protein-alpha (C/EBPalpha (显示 CEBPA 抗体)) directly regulates Kruppel-like factor 4 (Klf4 (显示 KLF4 抗体)) expression and increasing the levels of histone demethylase (显示 MBD2 抗体) Lsd1 (显示 KDM1A 抗体) and transcription factor Brd4 in B cell.

BRD4 抗原简介

Antigen Summary

The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15\;19)(q13\;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.

Alternative names and synonyms associated with BRD4

  • bromodomain containing 4 (brd4) 抗体
  • bromodomain containing 4 (BRD4) 抗体
  • bromodomain containing 4 (Brd4) 抗体
  • BRD4 抗体
  • brd4-b 抗体
  • Brd5 抗体
  • CAP 抗体
  • fb18g03 抗体
  • HUNK1 抗体
  • HUNKI 抗体
  • MCAP 抗体
  • WI-11513 抗体
  • wu:fb18g03 抗体

Protein level used designations for BRD4

Bromodomain-containing protein 4B , bromodomain-containing protein 4B , bromodomain containing 4 , bromodomain-containing protein 4 , bromodomain 4 , bromodomain-containing protein 4-like , bromodomain containing protein 4 , bromodomain-containing 4 , chromosome-associated protein , bromodomain-containing 5 , fsh-like protein , mitotic chromosome-associated protein

GENE ID SPECIES
446381 Xenopus laevis
455794 Pan troglodytes
570531 Danio rerio
100062072 Equus caballus
100216259 Xenopus (Silurana) tropicalis
100409351 Callithrix jacchus
100463607 Ailuropoda melanoleuca
100074736 Ornithorhynchus anatinus
100352214 Oryctolagus cuniculus
100533540 Sus scrofa
100593625 Nomascus leucogenys
23476 Homo sapiens
484869 Canis lupus familiaris
614048 Bos taurus
57261 Mus musculus
362844 Rattus norvegicus
anti-BRD4 (BRD4) 抗体 精选生产商
您还需要查找其他产品吗?