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PLAT 蛋白

(Plasminogen Activator, Tissue (PLAT))
This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding\; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
PLAT Protein (AA 1-562) (GST tag) PLAT Protein (AA 1-562) (GST tag) PLAT Protein (AA 1-562) (GST tag) (ABIN2566071)

PLAT 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

PLAT Protein (AA 311-562) (His tag) PLAT Protein (AA 311-562) (His tag) PLAT Protein (AA 311-562) (His tag) (ABIN3074639)

Crystallography grade PLAT 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys

PLAT Protein (AA 36-310) (His tag) PLAT Protein (AA 36-310) (His tag) PLAT Protein (AA 36-310) (His tag) (ABIN3074638)

Crystallography grade PLAT 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys

PLAT 蛋白 by Grade

Find PLAT 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

PLAT 蛋白 by Origin

Find PLAT 蛋白 for a variety of species such as anti-Human PLAT, anti-Mouse PLAT, anti-Rat PLAT. The species listed below are among those available. Click on a link to go to the corresponding products.

PLAT 蛋白 by Source

Here you will find PLAT 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

PLAT 蛋白 by 蛋白类型

Here you can find PLAT 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

PLAT 蛋白 by 应用范围

Find PLAT 蛋白 validated for a specific application such as SDS, WB, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

PLAT 蛋白 by 生物活性

Find PLAT 蛋白 with a specific 生物活性. The 生物活性 listed below are among those available. Click on a link to go to the corresponding products.

Popular PLAT 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN2566071
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3074639
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3074638
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132836
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132835
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3074637
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132837
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source
Validations
Cat. No. ABIN1111994
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7504551
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
Cat. No. ABIN7504553
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
Cat. No. ABIN7504552
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
Cat. No. ABIN7505738
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7404083
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7390724
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source CHO Cells
Validations
Cat. No. ABIN5569484
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our PLAT 蛋白

Wang, Luo, Masci, Crawford, Xiao: "Influence of Interleukin-1 Beta on Platelet-Poor Plasma Clot Formation: A Potential Impact on Early Bone Healing." in: PloS one, Vol. 11, Issue 2, pp. e0149775, (2016) (PubMed).

Bongoni, Kiermeir, Schnider, Jenni, Garimella, Bähr, Klymiuk, Wolf, Ayares, Voegelin, Constantinescu, Seebach, Rieben: "Transgenic Expression of Human CD46 on Porcine Endothelium: Effect on Coagulation and Fibrinolytic Cascades During Ex Vivo Human-to-Pig Limb Xenoperfusions." in: Transplantation, (2015) (PubMed).

Harr, Moore, Chin, Chapman, Ghasabyan, Stringham, Banerjee, Silliman: "Viscoelastic hemostatic fibrinogen assays detect fibrinolysis early." in: European journal of trauma and emergency surgery : official publication of the European Trauma Society, Vol. 41, Issue 1, pp. 49-56, (2015) (PubMed).

Kim, Tirloni, Radulovic, Lewis, Bakshi, Hill, da Silva Vaz, Logullo, Termignoni, Mulenga: "Conserved Amblyomma americanum tick Serpin19, an inhibitor of blood clotting factors Xa and XIa, trypsin and plasmin, has anti-haemostatic functions." in: International journal for parasitology, Vol. 45, Issue 9-10, pp. 613-27, (2015) (PubMed).

Mantuano, Lam, Shibayama, Campana, Gonias: "The NMDA receptor functions independently and as an LRP1 co-receptor to promote Schwann cell survival and migration." in: Journal of cell science, (2015) (PubMed).

Lin, Jin, Hu: "Tissue-type plasminogen activator (tPA) promotes M1 macrophage survival through p90 ribosomal S6 kinase (RSK) and p38 mitogen-activated protein kinase (MAPK) pathway." in: The Journal of biological chemistry, Vol. 290, Issue 12, pp. 7910-7, (2015) (PubMed).

Shahrour, Keck, Jankun: "Application of long-acting VLHL PAI-1 during sutureless partial nephrectomy in mice reduces bleeding." in: BioMed research international, Vol. 2015, pp. 392862, (2015) (PubMed).

Kindell, Keck, Jankun: "Comparison between the clot-protecting activity of a mutant plasminogen activator inhibitor-1 with a very long half-life and 6-aminocaproic acid." in: Experimental and therapeutic medicine, Vol. 9, Issue 6, pp. 2339-2343, (2015) (PubMed).

Chen, Chu, Brumberg: "Experience-dependent regulation of tissue-type plasminogen activator in the mouse barrel cortex." in: Neuroscience letters, Vol. 599, pp. 152-7, (2015) (PubMed).

Wu, Torre, Cuellar-Giraldo, Cheng, Yi, Bichler, García, Yepes: "Tissue-type plasminogen activator triggers the synaptic vesicle cycle in cerebral cortical neurons." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, (2015) (PubMed).

Aliases for PLAT 蛋白

plasminogen activator, tissue type (PLAT) 蛋白
plasminogen activator, tissue (Plat) 蛋白
plasminogen activator, tissue type (Plat) 蛋白
plasminogen activator, tissue (PLAT) 蛋白
plasminogen activator, tissue (plat) 蛋白
plasminogen activator, tissue type (plat) 蛋白
chromosome 20 open reading frame 181 (C20orf181) 蛋白
plasminogen activator, tissue L homeolog (plat.L) 蛋白
AU020998 蛋白
AW212668 蛋白
D8Ertd2e 蛋白
PATISS 蛋白
Plat 蛋白
plat 蛋白
T-PA 蛋白
t-pa 蛋白
TPA 蛋白
tPA 蛋白
tpa 蛋白
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