Chemokine (C-C Motif) Ligand 2 (CCL2) ELISA试剂盒产品概述

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Chemokine (C-C Motif) Ligand 2 ELISA试剂盒 (CCL2)
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别名:
AI323594, GDCF-2, HC11, HSMCR30, JE, MCAF, MCP-1, MCP-1A, MCP1, MCP1A, SCYA2, Sigje, SMC-CF

引用最多的Chemokine (C-C Motif) Ligand 2 ELISA试剂盒

  1. Rat (Rattus) CCL2 ELISA Kit for Sandwich ELISA - ABIN625210 : Ergenoğlu, Yeniel, Erbaş, Aktuğ, Yildirim, Ulukuş, Taskiran: Regression of endometrial implants by resveratrol in an experimentally induced endometriosis model in rats. in Reproductive sciences (Thousand Oaks, Calif.) 2013 (PubMed)
    Show all 24 references for 625210

  2. Mouse (Murine) CCL2 ELISA Kit for Sandwich ELISA - ABIN625159 : Williams, Jiang, Cochran, Dorsam, Graves: Regulated expression of monocyte chemoattractant protein-1 in normal human osteoblastic cells. in The American journal of physiology 1992 (PubMed)
    Show all 19 references for 625159

  3. Mouse (Murine) CCL2 ELISA Kit for Sandwich ELISA - ABIN1980569 : Novaes, Santos, Cupertino, Bastos, Oliveira, Carvalho, Neves, Oliveira, Talvani: Trypanosoma cruzi infection and benznidazole therapy independently stimulate oxidative status and structural pathological remodeling of the liver tissue in mice. in Parasitology research 2015 (PubMed)
    Show all 14 references for 1980569

  4. Rabbit CCL2 ELISA Kit for Sandwich ELISA - ABIN415999 : Ohira, Inoue, Shobayashi, Iwao, Fukushima, Tanihara: Simultaneous increase in multiple proinflammatory cytokines in the aqueous humor in neovascular glaucoma with and without intravitreal bevacizumab injection. in Investigative ophthalmology & visual science 2015 (PubMed)
    Show all 4 references for 415999

  5. Human CCL2 ELISA Kit for Sandwich ELISA - ABIN365052 : Zheng, Qin, Ye, Chen, Wang, Yan, Luo, Liu, Zhou, Xiong, Ma, Li: Lactoferrin suppresses the Epstein-Barr virus-induced inflammatory response by interfering with pattern recognition of TLR2 and TLR9. in Laboratory investigation; a journal of technical methods and pathology 2014 (PubMed)
    Show all 3 references for 365052

  6. Pig (Porcine) CCL2 ELISA Kit for Sandwich ELISA - ABIN431300 : Kemenesi, Kurucz, Kepner, Dallos, Oldal, Herczeg, Vajdovics, Bányai, Jakab: Circulation of Dirofilaria repens, Setaria tundra, and Onchocercidae species in Hungary during the period 2011-2013. in Veterinary parasitology 2015 (PubMed)

适于 Chemokine (C-C Motif) Ligand 2 相互作用对的更多 ELISA 试剂盒

Human Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. a molecular mechanism of oxidized low density lipoprotein antibody on inhibition of oxLDL-induced ERK MAPK (显示 MAPK1 ELISA试剂盒) pathway and consequent MCP-1 release.

  2. tumor-promoting role for CCL2 acting through CCR2 on the tumor microenvironment

  3. conclude that MCP-1/CCL2 plays a significant role in the pathogenesis of sepsis, which has potentially important therapeutic implications

  4. Data suggest that MCP1/CCL2 induces activation/tyrosine phosphorylation of ARHGEF1/p115-RhoGEF (显示 ARHGEF1 ELISA试剂盒) and up-regulates RAC1 signaling in vascular smooth muscle cells (VSMCs); ARHGEF1 (显示 ARHGEF1 ELISA试剂盒) inhibition suppresses MCP1-induced VSMC migration and proliferation. (ARHGEF1 (显示 ARHGEF1 ELISA试剂盒) = Rho guanine nucleotide exchange factor 1 (显示 ARHGEF1 ELISA试剂盒); RAC1 = Rac (显示 AKT1 ELISA试剂盒) family small GTPase (显示 RACGAP1 ELISA试剂盒) 1; CCL2 = C-C motif chemokine ligand 2 (显示 CXCL2 ELISA试剂盒))

  5. A polarized secretion assay suggested that the silencing of endothelial myeloid-secretory impairs T effector transendothelial migration by reducing the preferential secretion of endothelial-produced CCL2

  6. In cultured macrophages, LPS (显示 IRF6 ELISA试剂盒)-induced expression of monocyte chemoattractant protein (MCP)-1 was suppressed by NaN3 through inhibition of STAT1 (显示 STAT1 ELISA试剂盒) and IkappaBzeta (显示 NFKBIZ ELISA试剂盒) activities.

  7. CCL2/CCR2 (显示 CCR2 ELISA试剂盒) axis is expressed in the majority of monocytoid Acute myeloid leukemia (显示 BCL11A ELISA试剂盒) blasts

  8. identified CCL2 as a novel KIT D816V-dependent key regulator of vascular cell migration and angiogenesis in systemic mastocytosis

  9. This study establishes ECL1i as the first allosteric inhibitor of CCR2 with functional selectivity.

  10. Constitutive expression of CCL2 by the mouse mammary epithelium induces a state of low level chronic inflammation that increases stromal density and elevates cancer risk. We propose that CCL2-driven inflammation contributes to the increased risk of breast cancer observed in women with high mammographic density.

Mouse (Murine) Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. this study demonstrates that killed probiotics can reduce viral disease severity and identify that the MCP-1 (显示 CPT1B ELISA试剂盒) pathway might act as a key mediator in the improved antiviral immune response

  2. tumor-promoting role for CCL2 acting through CCR2 on the tumor microenvironment

  3. type I interferons, besides their known antiviral properties, can initiate the recruitment and activation of leukocytes via induction of chemokine (显示 CCL1 ELISA试剂盒) expression including CCL2.

  4. In cultured macrophages, LPS (显示 TLR4 ELISA试剂盒)-induced expression of monocyte chemoattractant protein (MCP)-1 (显示 CPT1B ELISA试剂盒) was suppressed by NaN3 through inhibition of STAT1 (显示 STAT1 ELISA试剂盒) and IkappaBzeta (显示 NFKBIZ ELISA试剂盒) activities.

  5. study concludes that CCL2 signaling onto melanin-concentrating hormone (显示 PMCH ELISA试剂盒) neurons represents a core mechanism that relays peripheral inflammation to sickness behavior

  6. The increased migratory phenotypes are dependent on secreted factors, including the cytokine interleukin-6 (显示 IL6 ELISA试剂盒) and the chemokine (显示 CCL1 ELISA试剂盒) CCL2. We propose that Delta122p53 (and Delta133p53) acts in a similar manner to 'gain-of-function' mutant p53 (显示 TP53 ELISA试剂盒) proteins to promote migration, invasion and metastasis, which may contribute to poor survival in patients with Delta133p53-expressing tumours

  7. CCL5 (显示 CCL5 ELISA试剂盒) paradoxically limits macrophage accumulation in the injured kidney during renin (显示 REN ELISA试剂盒) angiotensin system (RAS) activation by constraining the proinflammatory actions of CCL2.

  8. This study establishes ECL1i as the first allosteric inhibitor of CCR2 with functional selectivity.

  9. Constitutive expression of CCL2 by the mouse mammary epithelium induces a state of low level chronic inflammation that increases stromal density and elevates cancer risk. We propose that CCL2-driven inflammation contributes to the increased risk of breast cancer observed in women with high mammographic density.

  10. the individual and combined actions of CCL2/CCR2 (显示 CCR2 ELISA试剂盒) and CX3CL1 (显示 CX3CL1 ELISA试剂盒)/CX3CR1 (显示 CX3CR1 ELISA试剂盒) in hypoxia-induced pulmonary hypertension in mice, is reported.

Cow (Bovine) Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. resence of type 2 diabetes negatively affects the work of cytokines and markers of fibrosis, as evidenced by higher levels of interleukin-1beta and monocyte chemoattractant protein-1, compared with patients without diabetes

  2. Studied SNPs in the bovine toll-like receptor 4 (TLR4 (显示 TLR4 ELISA试剂盒)) and monocyte chemo attractant protein-1(CCL2) genes.

  3. The LEP (显示 LEP ELISA试剂盒), IGF2 and CCL2 genes showed allelic expression imbalance in liver, kidney and pituitary glands of Polish Holstein-Friesian bulls.

  4. immune cells and endothelial cells can interact cooperatively to increase CCL2 secretion in the corpus luteum

Rabbit Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. Data show that peripheral blood endothelial progenitor cells can increase the expressions of chemokines CCL2 and CXCL12 (显示 CXCL12 ELISA试剂盒) and promote the migration of enhanced green fluorescent protein-positive bone marrow stromal cells to bone defect site.

  2. In a cerebral aneurysm, expression of MCP1 peaked after induction for one week, then decreased. MCP1 induced macrophage adhesion and infiltration in the artery wall of aneurysms, and contributed to the occurrence and development of brain aneurysm.

  3. Data show that the serum levels of mast cell tryptase, monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8 (显示 IL8 ELISA试剂盒)) decreased significantly in Dachengqi decoction treatment group.

  4. measurements of CCL2 and macrophages can serve as new inflammatory biomarkers to evaluate the safety of promising novel microbicides for prevention of HIV.

  5. Expression of MCP-1 was successfully inhibited by transfecting MCP-1 siRNA expression plasmid to the carotid artery, and the progression of atherosclerosis was restricted by RNAi-mediated silencing of MCP-1 expression.

Pig (Porcine) Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. CXCL10 (显示 CXCL10 ELISA试剂盒) protein was detected in serum from pigs infected with a high virulence African swine fever virus isolate. Levels of CCL2 mRNA were increased in pigs infected with the high virulence isolate compared to a low virulence isolate.

  2. Porcine CCL2 binding on Tuk4+SLA (显示 SLA ELISA试剂盒)-II- but not on Tuk4-SLA (显示 SLA ELISA试剂盒)-II+ cells was detected by using a CCL2-green fluorescence protein fusion protein.

  3. The protective properties of flavonoids, such as EGCG, against endothelial inflammation may be regulated in part though induction of HO-1 and subsequent activator protein-1 signaling.

  4. MCP-1 contributes to functional and structural impairment in the kidney in renal artery stenosis, mainly in the tubulointerstitial compartment

  5. Contrast media did not affect bone marrow cell viability/MCP-1 secretion.

  6. Porcine vessel wall injury via balloon arthroplasty upregulates expression of CCL2 by coronary artery transmural and perivascular cells in a sequential pattern.

  7. in the aortic arch expression of monocyte chemoattractant protein 1 (MCP-1) was upregulated, compared with the thoracic aorta

  8. Variable gene expression (eg, matrix metalloproteinase-9 (显示 MMP9 ELISA试剂盒), CCL2 and Lp-PLA(2 (显示 Lp-PLA2 ELISA试剂盒)) mRNAs), both in regard to the arterial bed and duration of disease, was associated with variable plaque development and progression.

  9. myocardial infarction induced proinflammatory gene and protein expression in peripheral blood mononuclear cells of tissue factor (显示 F3 ELISA试剂盒) cyclo-oxygenase-2, monocyte chemoattractant protein-1 and CRP (显示 CRP ELISA试剂盒)

Chemokine (C-C Motif) Ligand 2 (CCL2) 抗原简介

Antigen Summary

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.

Alternative names and synonyms associated with Chemokine (C-C Motif) Ligand 2 (CCL2)

  • chemokine (C-C motif) ligand 2 (CCL2) Elisa Kit
  • chemokine (C-C motif) ligand 2 (Ccl2) Elisa Kit
  • macrophage cationic peptide 1 (MCP-1) Elisa Kit
  • mast cell proteinase-1 (MCP1) Elisa Kit
  • AI323594 Elisa Kit
  • GDCF-2 Elisa Kit
  • HC11 Elisa Kit
  • HSMCR30 Elisa Kit
  • JE Elisa Kit
  • MCAF Elisa Kit
  • MCP-1 Elisa Kit
  • MCP-1A Elisa Kit
  • MCP1 Elisa Kit
  • MCP1A Elisa Kit
  • SCYA2 Elisa Kit
  • Sigje Elisa Kit
  • SMC-CF Elisa Kit

Protein level used designations for CCL2

small inducible cytokine A2 , C-C motif chemokine 2 , immediate-early serum-responsive JE protein , immediate-early serum-responsive protein JE , monocyte chemoattractant protein 1 , monocyte chemoattractant protein-1 , monocyte chemotactic protein 1 , small inducible gene JE , small-inducible cytokine A2 , monocyte chemotactic and activating factor , monocyte secretory protein JE , small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je) , small inducible cytokine subfamily A (Cys-Cys), member 2 , platelet-derived growth factor-inducible protein JE , acidic seminal fluid protein , monocyte chemotactic protein 1A , MCP-1 , chemokine CCL2/MCP-1 , CS-III , NP-1 , antiadrenocorticotropin peptide III , corticostatin III , corticostatin-3 , macrophage antibiotic peptide MCP-1 , SMCP-1A , mast cell protease 1A

GENE ID SPECIES
748205 Pan troglodytes
24770 Rattus norvegicus
6347 Homo sapiens
20296 Mus musculus
281043 Bos taurus
100009130 Oryctolagus cuniculus
397422 Sus scrofa
403981 Canis lupus familiaris
100135494 Cavia porcellus
100034136 Equus caballus
100172740 Pongo abelii
101120093 Ovis aries
574138 Macaca mulatta
100009115 Oryctolagus cuniculus
443546 Ovis aries
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