anti-Chemokine (C-C Motif) Ligand 2 (CCL2) 抗体产品概述

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anti-Chemokine (C-C Motif) Ligand 2 抗体 (CCL2)
在www.antibodies-online.cn可供559 Chemokine (C-C Motif) Ligand 2 (CCL2) 抗体的34不同的供货商。 再加上,我们可以发Chemokine (C-C Motif) Ligand 2 试剂盒 (191)Chemokine (C-C Motif) Ligand 2 蛋白 (130)和数多这个蛋白质的别的产品。 总共902 Chemokine (C-C Motif) Ligand 2产品已列进来了。
别名:
AI323594, GDCF-2, HC11, HSMCR30, JE, MCAF, MCP-1, MCP-1A, MCP1, MCP1A, SCYA2, Sigje, SMC-CF

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  1. Human Monoclonal CCL2 Primary Antibody for EIA - ABIN453918 : Matsushima, Larsen, DuBois, Oppenheim: Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line. in The Journal of experimental medicine 1989 (PubMed)
    Show all 9 references for 453918

  2. Mouse (Murine) Polyclonal CCL2 Primary Antibody for IF (p), IHC (p) - ABIN737676 : Guo, Feng, Yao, Sun, Zhu: Transplantation of endothelial progenitor cells in treating rats with IgA nephropathy. in BMC nephrology 2014 (PubMed)
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  3. Human Polyclonal CCL2 Primary Antibody for BP, ICC - ABIN446462 : Fet, Fiebeler, Klinge, Park, Barth, Thepen, Tolba: Reduction of activated macrophages after ischaemia-reperfusion injury diminishes oxidative stress and ameliorates renal damage. in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012 (PubMed)
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  4. Mouse (Murine) Monoclonal CCL2 Primary Antibody for IHC (fro), IHC (p) - ABIN1108186 : Zoja, Liu, Donadelli, Abbate, Testa, Corna, Taraboletti, Vecchi, Dong, Rollins, Bertani, Remuzzi: Renal expression of monocyte chemoattractant protein-1 in lupus autoimmune mice. in Journal of the American Society of Nephrology : JASN 1997 (PubMed)
    Show all 3 references for 1108186

  5. Cow (Bovine) Polyclonal CCL2 Primary Antibody for EIA, WB - ABIN401066 : Liptak, Sullivan, Henkes, Wijayagunawardane, Miyamoto, Davis, Rueda, Townson: Cooperative expression of monocyte chemoattractant protein 1 within the bovine corpus luteum: evidence of immune cell-endothelial cell interactions in a coculture system. in Biology of reproduction 2005 (PubMed)
    Show all 3 references for 401066

  6. Human Monoclonal CCL2 Primary Antibody for EIA, FACS - ABIN1108180 : Semple, Kossmann, Morganti-Kossmann: Role of chemokines in CNS health and pathology: a focus on the CCL2/CCR2 and CXCL8/CXCR2 networks. in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010 (PubMed)
    Show all 2 references for 1108180

  7. Dog (Canine) Polyclonal CCL2 Primary Antibody for IHC, WB - ABIN2792200 : Carulli, Spagnolo, Fonseca, Welsh, duBois, Black, Denton: Single-nucleotide polymorphisms in CCL2 gene are not associated with susceptibility to systemic sclerosis. in The Journal of rheumatology 2008 (PubMed)

  8. Human Polyclonal CCL2 Primary Antibody for FACS, IF - ABIN390653 : Bannon, Johnson, Michelhaugh, Hartley, Halter, David, Kapatos, Schmidt: A molecular profile of cocaine abuse includes the differential expression of genes that regulate transcription, chromatin, and dopamine cell phenotype. in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2014 (PubMed)

  9. Human Polyclonal CCL2 Primary Antibody for WB - ABIN446454 : Xiang, Dong, Liu, Wang, Shi, Wei, Hu, Gong: Inhibitory effects of suppressor of cytokine signaling 3 on inflammatory cytokine expression and migration and proliferation of IL-6/IFN-?-induced vascular smooth muscle cells. in Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2013 (PubMed)

更多抗Chemokine (C-C Motif) Ligand 2的相互作用对抗体

Human Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. tumor-promoting role for CCL2 acting through CCR2 on the tumor microenvironment

  2. conclude that MCP-1/CCL2 plays a significant role in the pathogenesis of sepsis, which has potentially important therapeutic implications

  3. Data suggest that MCP1/CCL2 induces activation/tyrosine phosphorylation of ARHGEF1/p115-RhoGEF (显示 ARHGEF1 抗体) and up-regulates RAC1 signaling in vascular smooth muscle cells (VSMCs); ARHGEF1 (显示 ARHGEF1 抗体) inhibition suppresses MCP1-induced VSMC migration and proliferation. (ARHGEF1 (显示 ARHGEF1 抗体) = Rho guanine nucleotide exchange factor 1 (显示 ARHGEF1 抗体); RAC1 = Rac (显示 AKT1 抗体) family small GTPase (显示 RACGAP1 抗体) 1; CCL2 = C-C motif chemokine ligand 2 (显示 CXCL2 抗体))

  4. A polarized secretion assay suggested that the silencing of endothelial myeloid-secretory impairs T effector transendothelial migration by reducing the preferential secretion of endothelial-produced CCL2

  5. In cultured macrophages, LPS (显示 IRF6 抗体)-induced expression of monocyte chemoattractant protein (MCP)-1 was suppressed by NaN3 through inhibition of STAT1 (显示 STAT1 抗体) and IkappaBzeta (显示 NFKBIZ 抗体) activities.

  6. CCL2/CCR2 (显示 CCR2 抗体) axis is expressed in the majority of monocytoid Acute myeloid leukemia (显示 BCL11A 抗体) blasts

  7. identified CCL2 as a novel KIT D816V-dependent key regulator of vascular cell migration and angiogenesis in systemic mastocytosis

  8. This study establishes ECL1i as the first allosteric inhibitor of CCR2 with functional selectivity.

  9. Constitutive expression of CCL2 by the mouse mammary epithelium induces a state of low level chronic inflammation that increases stromal density and elevates cancer risk. We propose that CCL2-driven inflammation contributes to the increased risk of breast cancer observed in women with high mammographic density.

  10. CCR4-deficient Treg and CCR2-deficient monocyticmyeloid-derived suppressor cells (MDSC) were defective in glioma accumulation.

Mouse (Murine) Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. tumor-promoting role for CCL2 acting through CCR2 on the tumor microenvironment

  2. type I interferons, besides their known antiviral properties, can initiate the recruitment and activation of leukocytes via induction of chemokine (显示 CCL1 抗体) expression including CCL2.

  3. In cultured macrophages, LPS (显示 TLR4 抗体)-induced expression of monocyte chemoattractant protein (MCP)-1 (显示 CPT1B 抗体) was suppressed by NaN3 through inhibition of STAT1 (显示 STAT1 抗体) and IkappaBzeta (显示 NFKBIZ 抗体) activities.

  4. study concludes that CCL2 signaling onto melanin-concentrating hormone (显示 PMCH 抗体) neurons represents a core mechanism that relays peripheral inflammation to sickness behavior

  5. The increased migratory phenotypes are dependent on secreted factors, including the cytokine interleukin-6 (显示 IL6 抗体) and the chemokine (显示 CCL1 抗体) CCL2. We propose that Delta122p53 (and Delta133p53) acts in a similar manner to 'gain-of-function' mutant p53 (显示 TP53 抗体) proteins to promote migration, invasion and metastasis, which may contribute to poor survival in patients with Delta133p53-expressing tumours

  6. CCL5 (显示 CCL5 抗体) paradoxically limits macrophage accumulation in the injured kidney during renin (显示 REN 抗体) angiotensin system (RAS) activation by constraining the proinflammatory actions of CCL2.

  7. This study establishes ECL1i as the first allosteric inhibitor of CCR2 with functional selectivity.

  8. Constitutive expression of CCL2 by the mouse mammary epithelium induces a state of low level chronic inflammation that increases stromal density and elevates cancer risk. We propose that CCL2-driven inflammation contributes to the increased risk of breast cancer observed in women with high mammographic density.

  9. the individual and combined actions of CCL2/CCR2 (显示 CCR2 抗体) and CX3CL1 (显示 CX3CL1 抗体)/CX3CR1 (显示 CX3CR1 抗体) in hypoxia-induced pulmonary hypertension in mice, is reported.

  10. CCL2 acting at the suprachiasmatic nuclei level is important for the circadian effects of immune activation.

Cow (Bovine) Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. resence of type 2 diabetes negatively affects the work of cytokines and markers of fibrosis, as evidenced by higher levels of interleukin-1beta and monocyte chemoattractant protein-1, compared with patients without diabetes

  2. Studied SNPs in the bovine toll-like receptor 4 (TLR4 (显示 TLR4 抗体)) and monocyte chemo attractant protein-1(CCL2) genes.

  3. The LEP (显示 LEP 抗体), IGF2 and CCL2 genes showed allelic expression imbalance in liver, kidney and pituitary glands of Polish Holstein-Friesian bulls.

  4. immune cells and endothelial cells can interact cooperatively to increase CCL2 secretion in the corpus luteum

Rabbit Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. Data show that peripheral blood endothelial progenitor cells can increase the expressions of chemokines CCL2 and CXCL12 (显示 CXCL12 抗体) and promote the migration of enhanced green fluorescent protein-positive bone marrow stromal cells to bone defect site.

  2. In a cerebral aneurysm, expression of MCP1 peaked after induction for one week, then decreased. MCP1 induced macrophage adhesion and infiltration in the artery wall of aneurysms, and contributed to the occurrence and development of brain aneurysm.

  3. Data show that the serum levels of mast cell tryptase, monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8 (显示 IL8 抗体)) decreased significantly in Dachengqi decoction treatment group.

  4. measurements of CCL2 and macrophages can serve as new inflammatory biomarkers to evaluate the safety of promising novel microbicides for prevention of HIV.

  5. Expression of MCP-1 was successfully inhibited by transfecting MCP-1 siRNA expression plasmid to the carotid artery, and the progression of atherosclerosis was restricted by RNAi-mediated silencing of MCP-1 expression.

Pig (Porcine) Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. CXCL10 (显示 CXCL10 抗体) protein was detected in serum from pigs infected with a high virulence African swine fever virus isolate. Levels of CCL2 mRNA were increased in pigs infected with the high virulence isolate compared to a low virulence isolate.

  2. Porcine CCL2 binding on Tuk4+SLA (显示 SLA 抗体)-II- but not on Tuk4-SLA (显示 SLA 抗体)-II+ cells was detected by using a CCL2-green fluorescence protein fusion protein.

  3. The protective properties of flavonoids, such as EGCG, against endothelial inflammation may be regulated in part though induction of HO-1 and subsequent activator protein-1 signaling.

  4. MCP-1 contributes to functional and structural impairment in the kidney in renal artery stenosis, mainly in the tubulointerstitial compartment

  5. Contrast media did not affect bone marrow cell viability/MCP-1 secretion.

  6. Porcine vessel wall injury via balloon arthroplasty upregulates expression of CCL2 by coronary artery transmural and perivascular cells in a sequential pattern.

  7. in the aortic arch expression of monocyte chemoattractant protein 1 (MCP-1) was upregulated, compared with the thoracic aorta

  8. Variable gene expression (eg, matrix metalloproteinase-9 (显示 MMP9 抗体), CCL2 and Lp-PLA(2 (显示 Lp-PLA2 抗体)) mRNAs), both in regard to the arterial bed and duration of disease, was associated with variable plaque development and progression.

  9. myocardial infarction induced proinflammatory gene and protein expression in peripheral blood mononuclear cells of tissue factor (显示 F3 抗体) cyclo-oxygenase-2, monocyte chemoattractant protein-1 and CRP (显示 CRP 抗体)

Chemokine (C-C Motif) Ligand 2 (CCL2) 抗原简介

Antigen Summary

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.

Alternative names and synonyms associated with Chemokine (C-C Motif) Ligand 2 (CCL2)

  • chemokine (C-C motif) ligand 2 (CCL2) 抗体
  • chemokine (C-C motif) ligand 2 (Ccl2) 抗体
  • macrophage cationic peptide 1 (MCP-1) 抗体
  • mast cell proteinase-1 (MCP1) 抗体
  • AI323594 抗体
  • GDCF-2 抗体
  • HC11 抗体
  • HSMCR30 抗体
  • JE 抗体
  • MCAF 抗体
  • MCP-1 抗体
  • MCP-1A 抗体
  • MCP1 抗体
  • MCP1A 抗体
  • SCYA2 抗体
  • Sigje 抗体
  • SMC-CF 抗体

Protein level used designations for CCL2

small inducible cytokine A2 , C-C motif chemokine 2 , immediate-early serum-responsive JE protein , immediate-early serum-responsive protein JE , monocyte chemoattractant protein 1 , monocyte chemoattractant protein-1 , monocyte chemotactic protein 1 , small inducible gene JE , small-inducible cytokine A2 , monocyte chemotactic and activating factor , monocyte secretory protein JE , small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je) , small inducible cytokine subfamily A (Cys-Cys), member 2 , platelet-derived growth factor-inducible protein JE , acidic seminal fluid protein , monocyte chemotactic protein 1A , MCP-1 , chemokine CCL2/MCP-1 , CS-III , NP-1 , antiadrenocorticotropin peptide III , corticostatin III , corticostatin-3 , macrophage antibiotic peptide MCP-1 , SMCP-1A , mast cell protease 1A

GENE ID SPECIES
748205 Pan troglodytes
24770 Rattus norvegicus
6347 Homo sapiens
20296 Mus musculus
281043 Bos taurus
100009130 Oryctolagus cuniculus
397422 Sus scrofa
403981 Canis lupus familiaris
100135494 Cavia porcellus
100034136 Equus caballus
100172740 Pongo abelii
101120093 Ovis aries
574138 Macaca mulatta
100009115 Oryctolagus cuniculus
443546 Ovis aries
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