anti-ABCA1 (ABCA1) 抗体产品概述

Full name:
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 抗体 (ABCA1)
在www.antibodies-online.cn可供194 ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) 抗体的26不同的供货商。 再加上,我们可以发ABCA1 试剂盒 (42)ABCA1 蛋白 (8)和数多这个蛋白质的别的产品。 总共247 ABCA1产品已列进来了。
别名:
ABC-1, Abc1, ABCA1, Arabidopsis thaliana ATP-binding cassette A1, AtABCA1, ATP-binding cassette A1, CERP, HDLDT1, TGD
列出全部抗体 基因 基因ID UniProt
ABCA1 19 O95477
ABCA1 313210  
ABCA1 11303 P41233

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  1. Chicken Polyclonal ABCA1 Primary Antibody for ChIP, ELISA - ABIN152883 : Krimbou, Denis, Haidar, Carrier, Marcil, Genest: Molecular interactions between apoE and ABCA1: impact on apoE lipidation. in Journal of lipid research 2004 (PubMed)
    Show all 253 references for 152883

  2. Mouse (Murine) Monoclonal ABCA1 Primary Antibody for IHC (p), WB - ABIN268899 : Zhou, Choi, Li, Xu, Herz: LRP1 controls cPLA2 phosphorylation, ABCA1 expression and cellular cholesterol export. in PLoS ONE 2009 (PubMed)
    Show all 6 references for 268899

  3. Human Polyclonal ABCA1 Primary Antibody for WB - ABIN3044206 : Shang, Yu, Wang, Chen, Fang, Yang, Zhou, Nie, Zhou, Zhou: Fibroblast growth factor 21 enhances cholesterol efflux in THP-1 macrophage-derived foam cells. in Molecular medicine reports 2014 (PubMed)
    Show all 5 references for 3044206

  4. Human Polyclonal ABCA1 Primary Antibody for WB - ABIN3043773 : Chen: Effects of Chinese Herbal Compound "Xuemai Ning"on Rabbit Atherosclerosis Model and Expression of ABCA1. in International journal of biomedical science : IJBS 2013 (PubMed)
    Show all 5 references for 3043773

  5. Human Monoclonal ABCA1 Primary Antibody for CyTOF, FACS - ABIN4277133 : Wang, Zhang, Chou, Liang, Gu, Ma: Cyclosporine stimulates the renal epithelial sodium channel by elevating cholesterol. in American journal of physiology. Renal physiology 2009 (PubMed)
    Show all 5 references for 4277133

  6. Mouse (Murine) Monoclonal ABCA1 Primary Antibody for FACS - ABIN2477222 : Zarubica, Trompier, Chimini: ABCA1, from pathology to membrane function. in Pflügers Archiv : European journal of physiology 2007 (PubMed)

  7. Cow (Bovine) Polyclonal ABCA1 Primary Antibody for WB - ABIN2781512 : Fu, Mukhamedova, Ip, DSouza, Henley, DiTommaso, Kesani, Ditiatkovski, Jones, Lane, Jennings, Smyth, Kile, Sviridov: ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis. in Cell metabolism 2013 (PubMed)

  8. Human Polyclonal ABCA1 Primary Antibody for IF (p), IHC (p) - ABIN732188 : Jia, Song, Yang, Ma, Li, Lu, Cao, Zhang, Zhu, Wang, Leng, Cao, Du, Xu: Effects of Tanshinone IIA on the modulation of miR‑33a and the SREBP‑2/Pcsk9 signaling pathway in hyperlipidemic rats. in Molecular medicine reports 2016 (PubMed)

更多抗ABCA1的相互作用对抗体

Human ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) interaction partners

  1. there is an NFATc1 (显示 NFATC1 抗体)/ABCA1-dependent mechanism in which local TNF (显示 TNF 抗体) is sufficient to cause free cholesterol-dependent podocyte injury irrespective of TNF (显示 TNF 抗体), TNFR1 (显示 TNFRSF1A 抗体), or TNFR2 (显示 TNFRSF1B 抗体) serum levels

  2. Reduced platelet count, but no major platelet function abnormalities, are associated with loss-of-function ATP-binding cassette-1 gene mutations.

  3. Study report the cryo-EM structure of human ABCA1 with nominal resolutions of 4.1 A for the overall structure and 3.9 A for the massive extracellular domain. The nucleotide-binding domains display a nucleotide-free state, while the two transmembrane domains contact each other through a narrow interface in the intracellular leaflet of the membrane.

  4. ABCB1 (显示 ABCB1 抗体) status is significantly associated with chemo-resistance and poor prognosis in patients with epithelial ovarian cancer

  5. ABCA1 mediates ApoA-I (显示 APOA1 抗体) and ApoA-I (显示 APOA1 抗体) mimetic peptide mobilization of extracellular cholesterol microdomains deposited by macrophages.

  6. EEPD1 is a novel LXR (显示 NR1H3 抗体)-regulated gene in macrophages and that it promotes cellular cholesterol efflux by controlling cellular levels and activity of ABCA1.

  7. This is the first report showing evidence of FTO (显示 FTO 抗体) and ABCA1 gene variant interactions affecting BMI, which may explain previously reported population differences

  8. Pim (显示 PIM1 抗体)-1L protects hepatic ABCA1 from lysosomal degradation by facilitating the physical interaction between ABCA1 and liver X receptor beta (显示 NR1H2 抗体) and subsequent stabilization of the ABCA1-Pim (显示 PIM1 抗体)-1L complex and thereby regulates the circulating level of high-density lipoprotein.

  9. High expression of ABCA1 is associated with high carotid intima-media thickness.

  10. Thyrotropin regulated cholesterol content and ABCA1 expression in hepG2 cells.

Cow (Bovine) ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) interaction partners

  1. our results highlight the importance of the LXR (显示 NR1H3 抗体)/ABCA1 system in brain pericytes and suggest a new role for these cells in brain cholesterol homeostasis.

  2. The expression and distribution of the bovine ABCA1 transporter using quantitative PCR and the sequencing of the entire ABCA1 coding region, including the proximal promoter region, are reported.

  3. Aortic endothelial cells transcytose high-density lipoproteins by mechanisms that involve either SR-BI (显示 SCARB1 抗体) or ABCG1 (显示 ABCG1 抗体) but not ABCA1.

Pig (Porcine) ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) interaction partners

  1. ABCA1 promoter variants affect transcription activity and plasma HDL (显示 HSD11B1 抗体) level in pigs

  2. ABCA1 was up-regulated in monocytes of hypercholesterolemic pigs via oxidized-LDL and prior to development coronary atherosclerosis.

  3. Both region-specific and ubiquitous (ABCA1) phenotype changes were identified as early prelesional responses of the endothelium to hypercholesterolemia

Rabbit ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) interaction partners

  1. CSL112 elevation of ABCA1-dependent efflux may target atherosclerotic plaque for cholesterol removal.

Mouse (Murine) ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) interaction partners

  1. apoA-I (显示 APOA1 抗体)/ABCA1-mediated cholesterol efflux without STAT3 (显示 STAT3 抗体) activation can reduce proinflammatory cytokine expression in macrophages.

  2. Our data indicate that a combination of vildagliptin and pravastatin significantly induces the expression of LXR (显示 NR1H3 抗体)-ABCA1/ABCG1 (显示 ABCG1 抗体) cascade and improves cholesterol efflux (P > 0.05) in adipocytes. Our data may explain, at least in part, the improvement in HDL (显示 HSD11B1 抗体)-C levels observed in patients receiving both medications

  3. The findings obtained from apoE (显示 APOE 抗体)-/- mice provide epigenetic insights into how EZH2 (显示 EZH2 抗体) increases the risk of atherosclerotic heart disease. One of the pathways by which EZH2 (显示 EZH2 抗体) leads to lipid accumulation and foam cell formation is via epigenetic downregulation of ABCA1 expression.

  4. Overexpressed NHE1 suppresses the expression of ABCA1 protein via increasing the calpain activity in RAW264.7 cells.

  5. Endothelial cholesterol efflux pathways mediated by ABCA1 and ABCG1 (显示 ABCG1 抗体) are nonredundant and atheroprotective, reflecting preservation of endothelial NO synthase (显示 NOS 抗体) activity and suppression of endothelial inflammation, especially in regions of disturbed arterial blood flow.

  6. ABCA1 mediates ApoA-I (显示 APOA1 抗体) and ApoA-I (显示 APOA1 抗体) mimetic peptide mobilization of extracellular cholesterol microdomains deposited by macrophages.

  7. ARF6 (显示 ARF6 抗体)-dependent pathway is the predominant route responsible for the ABCA1 internalization and degradation, whereas ARF6 (显示 ARF6 抗体)-independent endocytic pathways may contribute to ABCA1 recycling and efflux of intracellular cholesterol.

  8. EEPD1 is a novel LXR (显示 NR1H3 抗体)-regulated gene in macrophages and that it promotes cellular cholesterol efflux by controlling cellular levels and activity of ABCA1.

  9. Pim (显示 PIM1 抗体)-1L protects hepatic ABCA1 from lysosomal degradation by facilitating the physical interaction between ABCA1 and liver X receptor beta (显示 NR1H2 抗体) and subsequent stabilization of the ABCA1-Pim (显示 PIM1 抗体)-1L complex and thereby regulates the circulating level of high-density lipoprotein.

  10. Nucleolin (显示 NCL 抗体) protects macrophages from oxLDL-induced foam cell formation in hyperlipidemia through up-regulating ABCA1 expression.

ABCA1 抗原简介

Antigen Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.

Alternative names and synonyms associated with ABCA1

  • ATP-binding cassette, sub-family A (ABC1), member 1 (ABCA1) 抗体
  • ATP-binding cassette, subfamily A (ABC1), member 1 (Abca1) 抗体
  • ATP-binding cassette, sub-family A (ABC1), member 1 (abca1) 抗体
  • ATP-binding cassette, sub-family A (ABC1), member 1 (Abca1) 抗体
  • ABC transporter A family member 1 (ABCA1) 抗体
  • ABC-1 抗体
  • Abc1 抗体
  • ABCA1 抗体
  • Arabidopsis thaliana ATP-binding cassette A1 抗体
  • AtABCA1 抗体
  • ATP-binding cassette A1 抗体
  • CERP 抗体
  • HDLDT1 抗体
  • TGD 抗体

Protein level used designations for ABCA1

ATP-binding cassette sub-family A member 1 , ATP-binding cassette transporter A1 , cholesterol efflux regulatory protein , membrane-bound , ATP-binding cassette, sub-family A (ABC1), member 1 , ATP-binding cassette, sub-family A member 1 , ATP-binding cassette transporter 1 , Cholesterol efflux regulatory protein , ATP-binding cassette transporter , ATP-binding cassette, sub-family A member 1-like , ATP-binding cassette sub-family A member 1-like , ATP-binding cassette 1

GENE ID SPECIES
19 Homo sapiens
313210 Rattus norvegicus
373945 Gallus gallus
464630 Pan troglodytes
481651 Canis lupus familiaris
535379 Bos taurus
716107 Macaca mulatta
100013781 Monodelphis domestica
100152112 Sus scrofa
100356765 Oryctolagus cuniculus
100441342 Pongo abelii
100483394 Ailuropoda melanoleuca
100491942 Xenopus (Silurana) tropicalis
11303 Mus musculus
100557081 Anolis carolinensis
818768 Arabidopsis thaliana
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