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GBA 抗体

(Glucosidase, Beta, Acid (GBA))
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010].
GBA 抗体  (AA 146-235) GBA 抗体  (AA 146-235) GBA 抗体 (AA 146-235) (ABIN561009)

GBA 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 2E2 unconjugated

GBA 抗体  (AA 117-214) GBA 抗体  (AA 117-214) GBA 抗体 (AA 117-214) (ABIN7434968)

GBA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

GBA 抗体 GBA 抗体 GBA 抗体 (ABIN7074062)

GBA 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

GBA 抗体 by 适用

Find GBA 抗体 for a variety of species such as anti-Human GBA, anti-Mouse GBA, anti-Rat GBA. The species listed below are among those available. Click on a link to go to the corresponding products.

GBA 抗体 by 应用范围

Find GBA 抗体 validated for a specific application such as WB, IHC, ELISA, ICC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

GBA 抗体 by 抗体来源

Find GBA 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

GBA 抗体 by 抗原表位

Find GBA 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

GBA 抗体 by 克隆形成能力

Find available monoclonal or polyclonal GBA 抗体. Click on a link to go to the corresponding products.

GBA 抗体 by 克隆

Find GBA 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

GBA 抗体 by 标记

Find GBA 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular GBA 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF
Validations
  • (5)
  • (6)
Cat. No. ABIN561009
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7434968
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC, IF
Validations
  • (5)
Cat. No. ABIN7074062
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7438208
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7248746
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN7267407
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ICC, IHC (p), IF
Validations
  • (3)
Cat. No. ABIN2854995
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7438832
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7153944
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN947903
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN515959
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN515957
Quantity 50 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (3)
Cat. No. ABIN2788767
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7177225
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN561008
Quantity 50 μL
Datasheet Datasheet

Latest Publications for our GBA 抗体

Bieri, Brahic, Bousset, Couthouis, Kramer, Ma, Nakayama, Monbureau, Defensor, Schüle, Shamloo, Melki, Gitler: "LRRK2 modifies α-syn pathology and spread in mouse models and human neurons." in: Acta neuropathologica, Vol. 137, Issue 6, pp. 961-980, (2019) (PubMed).

Massaro, Mattar, Wong, Sirka, Buckley, Herbert, Karlsson, Perocheau, Burke, Heales, Richard-Londt, Brandner, Huebecker, Priestman, Platt, Mills, Biswas, Cooper, Chan, Cheng, Waddington, Rahim: "Fetal gene therapy for neurodegenerative disease of infants." in: Nature medicine, Vol. 24, Issue 9, pp. 1317-1323, (2018) (PubMed).

Zancan, Bellesso, Costa, Salvalaio, Stroppiano, Hammond, Argenton, Filocamo, Moro: "Glucocerebrosidase deficiency in zebrafish affects primary bone ossification through increased oxidative stress and reduced Wnt/β-catenin signaling." in: Human molecular genetics, Vol. 24, Issue 5, pp. 1280-94, (2015) (PubMed).

Murphy, Gysbers, Abbott, Tayebi, Kim, Sidransky, Cooper, Garner, Halliday: "Reduced glucocerebrosidase is associated with increased ?-synuclein in sporadic Parkinson's disease." in: Brain : a journal of neurology, Vol. 137, Issue Pt 3, pp. 834-48, (2014) (PubMed).

Bendikov-Bar, Rapaport, Larisch, Horowitz: "Parkin-mediated ubiquitination of mutant glucocerebrosidase leads to competition with its substrates PARIS and ARTS." in: Orphanet journal of rare diseases, Vol. 9, pp. 86, (2014) (PubMed).

Bendikov-Bar, Horowitz: "Gaucher disease paradigm: from ERAD to comorbidity." in: Human mutation, Vol. 33, Issue 10, pp. 1398-407, (2012) (PubMed).

Bendikov-Bar, Ron, Filocamo, Horowitz: "Characterization of the ERAD process of the L444P mutant glucocerebrosidase variant." in: Blood cells, molecules & diseases, Vol. 46, Issue 1, pp. 4-10, (2011) (PubMed).

Campeau, Rafei, Boivin, Sun, Grabowski, Galipeau: "Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome." in: Blood, Vol. 114, Issue 15, pp. 3181-90, (2009) (PubMed).

Aliases for GBA 抗体

glucosylceramidase beta (GBA) 抗体
beta glucosidase 25 (BGLU25) 抗体
beta-glucosidase (PSPTO_3318) 抗体
beta-glucosidase (bglX) 抗体
Beta-glucosidase (bglA4) 抗体
glucosidase, beta, acid (Gba) 抗体
glucosylceramidase beta (Gba) 抗体
glucosylceramidase (LOC100399524) 抗体
beta-glucosidase (bglA.2) 抗体
bglX-2 (bglX-2) 抗体
glucosidase, beta, acid (GBA) 抗体
BETA-GLUCOSIDASE 抗体
betaGC 抗体
beta glucosidase 25 抗体
GBA1 抗体
GC 抗体
GCase 抗体
GCB 抗体
GLUC 抗体
PSPTO3318 抗体
PSPTO4290 抗体
T12J13.8 抗体
T12J13_8 抗体
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