anti-SKP1 (SKP1) 抗体产品概述

Full name:
anti-S-Phase Kinase-Associated Protein 1 抗体 (SKP1)
在www.antibodies-online.cn可供121 S-Phase Kinase-Associated Protein 1 (SKP1) 抗体的19不同的供货商。 再加上,我们可以发SKP1 蛋白 (25)SKP1 试剂盒 (14)和数多这个蛋白质的别的产品。 总共167 SKP1产品已列进来了。
15kDa, 2610043E24Rik, 2610206H23Rik, ARABIDOPSIS SKP1 HOMOLOGUE 1, ASK1, ATSKP1, EMC19, ocp-2, OCP-II, OCP2, p19A, p19Skp1, SKP1, Skp1a, S phase kinase-associated protein 1, T4O12.17, T4O12_17, Tceb1l, UFO INTERACTING PROTEIN 1, UIP1, zgc:73186

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引用最多的anti-SKP1 抗体

  1. Human Polyclonal SKP1 Primary Antibody for EIA, IP - ABIN117959 : Wang, He, Wang, Wang, Zhai, Zhou, Zhang, Zhai, Feng, Han: [Impact of Donor KIR2DS5 Genotype on Outcome Following Haploidentical Hematopoietic Stem Cell Transplantation.] in Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology 2008 (PubMed)
    Show all 13 references for 117959

  2. Human Polyclonal SKP1 Primary Antibody for EIA, WB - ABIN357264 : Wu, Xu, Schulman, Jeffrey, Harper, Pavletich: Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase. in Molecular cell 2003 (PubMed)
    Show all 5 references for 357264

  3. Human Monoclonal SKP1 Primary Antibody for IF, WB - ABIN393543 : Davies, Kaplan: Hsp90-Sgt1 and Skp1 target human Mis12 complexes to ensure efficient formation of kinetochore-microtubule binding sites. in The Journal of cell biology 2010 (PubMed)
    Show all 5 references for 393543

  4. Chicken Monoclonal SKP1 Primary Antibody for BI, IP - ABIN968019 : Carrano, Pagano: Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression. in The Journal of cell biology 2001 (PubMed)
    Show all 4 references for 968019

  5. Human Monoclonal SKP1 Primary Antibody for ICC, FACS - ABIN969397 : Werden, Lanchbury, Shattuck, Neff, Dufford, McFadden: The myxoma virus m-t5 ankyrin repeat host range protein is a novel adaptor that coordinately links the cellular signaling pathways mediated by Akt and Skp1 in virus-infected cells. in Journal of virology 2009 (PubMed)

  6. Human Polyclonal SKP1 Primary Antibody for IP, WB - ABIN233777 : Shiraishi, Zhou, Aoki, Sato, Chiba, Tanaka, Yoshida, Nabeshima, Nabeshima, Tamura: TBP-interacting protein 120B (TIP120B)/cullin-associated and neddylation-dissociated 2 (CAND2) inhibits SCF-dependent ubiquitination of myogenin and accelerates myogenic differentiation. in The Journal of biological chemistry 2007 (PubMed)

  7. Human Monoclonal SKP1 Primary Antibody for FACS, IHC - ABIN969398 : Plesca, Mazumder, Gama, Matsuyama, Almasan: A C-terminal fragment of Cyclin E, generated by caspase-mediated cleavage, is degraded in the absence of a recognizable phosphodegron. in The Journal of biological chemistry 2008 (PubMed)


Human S-Phase Kinase-Associated Protein 1 (SKP1) interaction partners

  1. Segregation analysis revealed that variants c.475T>G in SKP1, c.671G>A in PROB1, and c.527G>A in IL17B in the 5q31.1-q35.3 linkage region, and c.850G>A in HKDC1 in the 10q22 locus completely segregated with the phenotype in the studied Keratoconus family

  2. Both the F-box domain of Skp2 and Skp1-Skp2 domain motions displaying preferential conformational control can together facilitate polyubiquitination of a wide variety of substrates.

  3. Skp1 is critical to lung cancer pathogenesis

  4. Data show that epithelial-mesenchymal transition (EMT (显示 ITK 抗体))-transcription factors can be dynamically degraded by an atypical ubiquitin E3 ligase complex Skp1-Pam (显示 PAM 抗体)-Fbxo45 (显示 FBXO45 抗体) (SPFFbxo45).

  5. We discuss how these results can explain the rapid association of Cdc34 (显示 CDC34 抗体) and Skp1-cullin-F-box ligase (SCF (显示 KITLG 抗体)).

  6. SKP1 variation modifies association between Parkinson's disease and ubiquitin-proteasome system-inhibiting pesticides

  7. Studies indicate that in SCFs, Rbx1 serves as the RING-containing enzyme, Cul1 (显示 CUL1 抗体) is the Cullin scaffold, and Skp1 is an adaptor, which serves to link the beta-TrCP (显示 BTRC 抗体) F-box substrate-specific factor to the rest of the ligase.

  8. Substrate binding promotes formation of the Skp1-Cul1 (显示 CUL1 抗体)-Fbxl3 (显示 FBXL3 抗体) (SCF (显示 KITLG 抗体)(Fbxl3 (显示 FBXL3 抗体))) protein complex.

  9. Skp1-Cul1 (显示 CUL1 抗体)-F-box ubiquitin ligase (SCF (显示 KITLG 抗体)(betaTrCP (显示 BTRC 抗体)))-mediated destruction of the ubiquitin-specific protease USP37 (显示 USP37 抗体) during G2-phase promotes mitotic entry

  10. Deconjugation of Nedd8 (显示 NEDD8 抗体) from Cul1 (显示 CUL1 抗体) is directly regulated by Skp1-F-box and substrate, and the COP9 (显示 COPS8 抗体) signalosome inhibits deneddylated SCF (显示 KITLG 抗体) by a noncatalytic mechanism.

Cow (Bovine) S-Phase Kinase-Associated Protein 1 (SKP1) interaction partners

  1. The SCF (显示 KITLG 抗体)-complex gene expression has been characterized during bovine preimplantation development (显示 MTA2 抗体).

Arabidopsis thaliana S-Phase Kinase-Associated Protein 1 (SKP1) interaction partners

  1. How ASK1 might regulate protein stability and further downstream gene expression

  2. ABA induced the phosphorylation of three basic helix-loop-helix (bHLH) transcription factors, called AKSs (ABA-responsive kinase substrates; AKS1, AKS2, and AKS3), in Arabidopsis guard cells

  3. ASK1 and ASK2, are required for Agrobacterium-mediated plant transformation.

  4. ASK1 or ASK2 overexpression could rescue or partially rescue the Abscisic acid (ABA)insensitivity of abi5 (显示 ABI5 抗体)-1 mutants, respectively.

  5. ASK1 is predominately expressed from leptotene to pachytene, and negatively regulates recombination in Arabidopsis.

  6. Through the ASK1-mediated proteolysis pathway, ASK1 proteins showed pleiotropic functions including photomorphogenesis, circadian oscillation, post-translation process, stress-responses and cell expansion or elongation.

  7. ASK1 is required for normal SYN1 distribution during meiotic prophase I and suggest that ask1 associated defects may be primarily related to SYN1 mislocalization.

  8. These results raise the interesting possibility that ASK1 controls chromatin structure by targeting of either an early regulator of meiotic progression or possibly matrix attachment proteins for destruction.

Mouse (Murine) S-Phase Kinase-Associated Protein 1 (SKP1) interaction partners

  1. Lysine 29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response.

  2. Substrate binding promotes formation of the Skp1-Cul1 (显示 CUL1 抗体)-Fbxl3 (显示 FBXL3 抗体) (SCF (显示 KITLG 抗体)(Fbxl3 (显示 FBXL3 抗体))) protein complex.

  3. In this review, deficiency of SKP1A in SN4741 cells closely recapitulates cardinal (显示 CARD8 抗体) features of the dopamine (DA) neuron pathology of human Parkinson's disease, such as decreased expression of DA phenotypic markers and cell cycle aberrations.

  4. phosphorylated NIPA (显示 ZC3HC1 抗体) is degraded in late mitosis in an APC (显示 APC 抗体)/C(Cdh1 (显示 CDH1 抗体))-dependent manner

  5. Skp1 is a potential modifier in sporadic Parkinson disease neurodegeneration

Guinea Pig S-Phase Kinase-Associated Protein 1 (SKP1) interaction partners

  1. study evaluated the conformational stabilities of OCP1 (显示 FBXO2 抗体) and OCP2

SKP1 抗原简介

Antigen Summary

This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.

Alternative names and synonyms associated with SKP1

  • S-phase kinase-associated protein 1 (skp1) 抗体
  • S-phase kinase-associated protein 1 (SKP1) 抗体
  • S-phase kinase-associated protein 1 (LOC100340043) 抗体
  • S-phase kinase-associated protein 1 (Skp1) 抗体
  • S-phase kinase-associated protein 1A (Skp1a) 抗体
  • S-phase kinase-associated protein 1A (Skp1) 抗体
  • 15kDa 抗体
  • 2610043E24Rik 抗体
  • 2610206H23Rik 抗体
  • ASK1 抗体
  • ATSKP1 抗体
  • EMC19 抗体
  • ocp-2 抗体
  • OCP-II 抗体
  • OCP2 抗体
  • p19A 抗体
  • p19Skp1 抗体
  • SKP1 抗体
  • Skp1a 抗体
  • S phase kinase-associated protein 1 抗体
  • T4O12.17 抗体
  • T4O12_17 抗体
  • Tceb1l 抗体
  • UIP1 抗体
  • zgc:73186 抗体

Protein level used designations for SKP1

S-phase kinase-associated protein 1 , SCF complex component , S-phase kinase-associated protein 1A , S-phase kinase-associated protein 1A (p19A) , OCP-2 , RNA polymerase II elongation factor-like protein OCP2 , SIII , cyclin A/CDK2-associated p19 , cyclin A/CDK2-associated protein p19 , cyclin-A/CDK2-associated protein p19 , organ of Corti protein 2 , organ of Corti protein II , p19skp1 , transcription elongation factor B , p19A

100195936 Salmo salar
100240716 Ovis aries
100340043 Oryctolagus cuniculus
100528639 Ictalurus punctatus
393716 Danio rerio
462063 Pan troglodytes
474682 Canis lupus familiaris
549273 Xenopus (Silurana) tropicalis
735335 Pan troglodytes
6500 Homo sapiens
287280 Rattus norvegicus
615427 Bos taurus
416319 Gallus gallus
100174716 Pongo abelii
380538 Xenopus laevis
843928 Arabidopsis thaliana
21402 Mus musculus
100135616 Cavia porcellus
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