CDK8 (CDK8) ELISA试剂盒产品概述

Full name:
Cyclin-Dependent Kinase 8 ELISA试剂盒 (CDK8)
在www.antibodies-online.cn可供19 Cyclin-Dependent Kinase 8 (CDK8) ELISA试剂盒的9不同的供货商。 再加上,我们可以发CDK8 抗体 (91)CDK8 蛋白 (15)和数多这个蛋白质的别的产品。 总共133 CDK8产品已列进来了。
别名:
K35, wu:fk95h11
list all ELISA KIts 基因 基因ID UniProt
CDK8 1024 P49336
CDK8 264064 Q8R3L8
CDK8    

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适于 CDK8 相互作用对的更多 ELISA 试剂盒

Human Cyclin-Dependent Kinase 8 (CDK8) interaction partners

  1. These results identify CDK8 as a novel downstream mediator of estrogen receptors (ER) and suggest the utility of CDK8 inhibitors for ER-positive breast cancer therapy

  2. Our data suggest for the first time that CDK8 appears to contribute to the malignant mechanism of LSCC and may represent a significant prognostic marker for LSCC patients.

  3. On stimulation of TLR9 (显示 TLR9 ELISA试剂盒), CDK8/19 positively regulates inflammatory gene transcription in cooperation with NF-kappaB (显示 NFKB1 ELISA试剂盒) and C/EBPbeta (显示 CEBPB ELISA试剂盒).

  4. Data suggest that, during neurogenesis, Mediator complex cyclin (显示 PCNA ELISA试剂盒)-dependent kinases (CDK8, CDK19 (显示 CDK19 ELISA试剂盒)) interact directly with PRC2 (polycomb (显示 CBX2 ELISA试剂盒) repressive complex 2) subunit EZH2 (enhancer of zeste homolog 2 (显示 EZH2 ELISA试剂盒)), as well as SUZ12 (suppressor of zeste 12 homolog (显示 SUZ12 ELISA试剂盒)).

  5. the expression of CDK8 and its interactive genes has a profound impact on the response to adjuvant therapy in breast cancer in accordance with the role of CDK8 in chemotherapy-induced tumor-supporting paracrine activities--{REVIEW}

  6. Data suggest that MED13 (显示 MED13 ELISA试剂盒), MED12 (显示 MED12 ELISA试剂盒), CDK8 and cyclin C (CycC (显示 CCNC ELISA试剂盒)) comprise a four-subunit "kinase" module of the Mediator complex that functions as a major ingress of oncogenic and developmental signaling/gene expression in humans. [REVIEW]

  7. our data provided evidence that CDK-8 played a significant role in colon cancer hepatic metastasis by regulating the Wnt (显示 WNT2 ELISA试剂盒)/beta-catenin (显示 CTNNB1 ELISA试剂盒) signal pathway

  8. Collectively, our results implicate Ste12 and Tec1 as general and important contributors to the Cdk8, RNAPII-CTD regulatory circuitry as it relates to the maintenance of genome integrity

  9. miR (显示 MLXIP ELISA试剂盒)-101 is a potent tumor repressor that directly represses CDK8 expression

  10. Mediator-associated kinases CDK8 and CDK19 (显示 CDK19 ELISA试剂盒) restrain increased activation of key super-enhancer-associated genes in acute myeloid leukaemia (AML (显示 RUNX1 ELISA试剂盒)) cells

Zebrafish Cyclin-Dependent Kinase 8 (CDK8) interaction partners

  1. Cloning, sequencing and developmental expression pattern of cyclin-dependent kinase 8.

Mouse (Murine) Cyclin-Dependent Kinase 8 (CDK8) interaction partners

  1. our findings uncover a tumour suppressor function for CDK8 in vivo and suggest that the role of CDK8 activity in driving oncogenesis is context-specific.

  2. The Skp2-mH2A1 (显示 H2AFY ELISA试剂盒)-CDK8 axis has a critical role in breast cancer development via dysregulation of the G2/M transition, polyploidy, cell growth dysregulation, and loss of tumor suppression.

  3. our results suggest that mTORC1 activation in NAFLD (显示 TSC2 ELISA试剂盒) and insulin (显示 INS ELISA试剂盒) resistance results in down-regulation of the CDK8-CycC (显示 CCNC ELISA试剂盒) complex and elevation of lipogenic protein expression.

  4. Constitutive phosphorylation of S727 depends on cyclin-dependent kinase 8 (CDK8).

  5. CDK8 is a key regulator of STAT1 (显示 STAT1 ELISA试剂盒) and antiviral responses.

  6. Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities

  7. This study illustrates a new gene-repressive mechanism of RIP140 (显示 NRIP1 ELISA试剂盒) that can affect the transcription machinery by directly interacting with CDK8.

  8. knockdown of CDK8 in cells depleted of mH2A suppresses the proliferative advantage induced by mH2A loss

  9. Results suggest that transcriptional repression of genes critical for early-cell-fate determination underlies the requirement of Cdk8 in embryogenesis.

  10. As receptor-activated Smads form transcriptional complexes, they are phosphorylated at an interdomain linker region by CDK8 and CDK9 (显示 CDK9 ELISA试剂盒), which are components of transcriptional mediator and elongation complexes.

Caenorhabditis elegans (C. elegans) Cyclin-Dependent Kinase 8 (CDK8) interaction partners

  1. The C. elegans CDK8 Mediator module regulates axon guidance decisions in the ventral nerve cord and during dorsal axon navigation.

CDK8 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery.

Alternative names and synonyms associated with CDK8

  • cyclin-dependent kinase 8 (LOC100353845) Elisa Kit
  • cyclin-dependent kinase 8 (CDK8) Elisa Kit
  • cyclin-dependent kinase 8 (cdk8) Elisa Kit
  • cyclin-dependent kinase 8 (Cdk8) Elisa Kit
  • cyclin-dependent kinase 8 (LOC100355706) Elisa Kit
  • Protein CDK-8 (cdk-8) Elisa Kit
  • K35 Elisa Kit
  • wu:fk95h11 Elisa Kit

Protein level used designations for CDK8

cyclin-dependent kinase 8 , CDK8 protein kinase , cell division protein kinase 8 , mediator complex subunit CDK8 , mediator of RNA polymerase II transcription subunit CDK8 , protein kinase K35 , mediator complex subunit cdk8 , mediator of RNA polymerase II transcription subunit cdk8

GENE ID SPECIES
100353845 Oryctolagus cuniculus
1024 Homo sapiens
373868 Danio rerio
447409 Xenopus laevis
428080 Gallus gallus
486035 Canis lupus familiaris
264064 Mus musculus
100524102 Sus scrofa
100355706 Oryctolagus cuniculus
172677 Caenorhabditis elegans
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