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CDK8 抗体

(Cyclin-Dependent Kinase 8 (CDK8))
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery. [provided by RefSeq, Jul 2008].
CDK8 抗体  (AA 375-464) CDK8 抗体  (AA 375-464) CDK8 抗体 (AA 375-464) (ABIN560302)

CDK8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6H5 unconjugated

CDK8 抗体  (AA 365-464) CDK8 抗体  (AA 365-464) CDK8 抗体 (AA 365-464) (ABIN6138329)

CDK8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

CDK8 抗体  (N-Term) CDK8 抗体  (N-Term) CDK8 抗体 (N-Term) (ABIN6257696)

CDK8 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

CDK8 抗体 by 适用

Find CDK8 抗体 for a variety of species such as anti-Human CDK8, anti-Mouse CDK8, anti-Rat CDK8. The species listed below are among those available. Click on a link to go to the corresponding products.

CDK8 抗体 by 应用范围

Find CDK8 抗体 validated for a specific application such as WB, ELISA, FACS, IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

CDK8 抗体 by 抗体来源

Find CDK8 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

CDK8 抗体 by 抗原表位

Find CDK8 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

CDK8 抗体 by 克隆形成能力

Find available monoclonal or polyclonal CDK8 抗体. Click on a link to go to the corresponding products.

CDK8 抗体 by 克隆

Find CDK8 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

CDK8 抗体 by 标记

Find CDK8 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular CDK8 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (7)
Cat. No. ABIN560302
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (3)
Cat. No. ABIN6138329
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, ICC, IF
Validations
  • (2)
Cat. No. ABIN6257696
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ChIP-seq, ChIP
Validations
  • (2)
Cat. No. ABIN6971509
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), IF (p)
Validations
  • (1)
Cat. No. ABIN670266
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7188619
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (1)
Cat. No. ABIN7441010
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6242788
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN3183844
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7266596
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN202585
Quantity 100 μL
Datasheet Datasheet
Reactivity Chicken, Dog, Horse, Human, Monkey, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
Cat. No. ABIN6749807
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN391759
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (2)
Cat. No. ABIN655911
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat, Zebrafish (Danio rerio)
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN7299158
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our CDK8 抗体

Han, Zheng, Ge, Wang, Xiang, Wang: "Downregulation of cyclin-dependent kinase 8 by microRNA-148a suppresses proliferation and invasiveness of papillary thyroid carcinomas." in: American journal of cancer research, Vol. 7, Issue 10, pp. 2081-2090, (2018) (PubMed).

Li, Tian, Ren, Chen, Wang, Ge, Wu, Sun, Liu, Xiao: "MicroRNA-101 is a potential prognostic indicator of laryngeal squamous cell carcinoma and modulates CDK8." in: Journal of translational medicine, Vol. 13, pp. 271, (2015) (PubMed).

Barette, Jariel-Encontre, Piechaczyk, Piette: "Human cyclin C protein is stabilized by its associated kinase cdk8, independently of its catalytic activity." in: Oncogene, Vol. 20, Issue 5, pp. 551-62, (2001) (PubMed).

Di Pietro, Rapisarda, Bonaiuto, Lizzio, Engel, Amico, Scalia, Amato, Grzeschik, Sichel, Purrello: "Genomics of the human genes encoding four TAFII subunits of TFIID, the three subunits of TFIIA, as well as CDK8 and SURB7." in: Somatic cell and molecular genetics, Vol. 25, Issue 3, pp. 185-9, (2001) (PubMed).

Akoulitchev, Chuikov, Reinberg: "TFIIH is negatively regulated by cdk8-containing mediator complexes." in: Nature, Vol. 407, Issue 6800, pp. 102-6, (2000) (PubMed).

Johnson, Walker: "Cyclins and cell cycle checkpoints." in: Annual review of pharmacology and toxicology, Vol. 39, pp. 295-312, (1999) (PubMed).

Rickert, Corden, Lees: "Cyclin C/CDK8 and cyclin H/CDK7/p36 are biochemically distinct CTD kinases." in: Oncogene, Vol. 18, Issue 4, pp. 1093-102, (1999) (PubMed).

Aliases for CDK8 抗体

cyclin dependent kinase 8 (CDK8) 抗体
cyclin-dependent kinase 8 (Cdk8) 抗体
cyclin-dependent kinase 8 (cdk8) 抗体
cyclin-dependent kinase 8 S homeolog (cdk8.S) 抗体
Cyclin-dependent kinase 8 (cdk-8) 抗体
cyclin-dependent kinase 8 (CDK8) 抗体
cyclin dependent kinase 19 (CDK19) 抗体
K35 抗体
wu:fk95h11 抗体
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