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抗Human CDC25C 抗体:
抗Mouse (Murine) CDC25C 抗体:
抗Rat (Rattus) CDC25C 抗体:
Human Monoclonal CDC25C Primary Antibody for BI, WB - ABIN967552
Peng, Graves, Thoma, Wu, Shaw, Piwnica-Worms: Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. in Science (New York, N.Y.) 1997
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Human Monoclonal CDC25C Primary Antibody for IHC, ELISA - ABIN1724739
Busch, Barton, Morgenstern, Götz, Günther, Noll, Montenarh: The G2/M checkpoint phosphatase cdc25C is located within centrosomes. in The international journal of biochemistry & cell biology 2007
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Human Polyclonal CDC25C Primary Antibody for IF (p), IHC (p) - ABIN1387108
Ghate, Chaudhuri, Sarkar, Sajem, Panja, Rout, Mandal: An antioxidant extract of tropical lichen, Parmotrema reticulatum, induces cell cycle arrest and apoptosis in breast carcinoma cell line MCF-7. in PLoS ONE 2013
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Human Polyclonal CDC25C Primary Antibody for IF (p), IHC (p) - ABIN746993
Yin, Jiang, Peng, Cui, Zhou, He, Zuo, Ouyang, Fan, Fang: The molecular mechanism of G2M cell cycle arrest induced by AFB1 in the jejunum. in Oncotarget 2016
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Human CDC25C Primary Antibody for IHC - ABIN965833
Chen, Zhang, Bower, Lu, Leonard, Ding, Castranova, Piwnica-Worms, Shi: Arsenite-induced Cdc25C degradation is through the KEN-box and ubiquitin-proteasome pathway. in Proceedings of the National Academy of Sciences of the United States of America 2002
Mdm2 (显示 MDM2 抗体) overexpression and Cdc25C downregulation delay cell cycle progression through the G2/M phase.
Xanthatin functions as a DNA-damaging agent in non-small cell lung carcinomas by activating Chk1 (显示 CHEK1 抗体)-mediated DDR (显示 DDR1 抗体) and lysosome-mediated degradation of Cdc25C.
Myelodysplastic syndrome -related P95 (显示 NBN 抗体) point mutants of SRSF2 (显示 SRSF2 抗体) lead to alternative splicing of CDC25C in a manner that is not dependent on the DNA damage response.
The aim of this review is to shed light on the role of four different phosphatases (PTEN (显示 PTEN 抗体), PP2A (显示 PPP2R4 抗体), CDC25 (显示 RASGRF1 抗体) and DUSP1 (显示 DUSP1 抗体)) in five different solid tumors (breast cancer, lung cancer, pancreatic cancer, prostate cancer and ovarian cancer), in order to better understand the most frequent and aggressive primary cancer of the central nervous system, glioblastoma.
Data show that TRIB2 (显示 TRIB2 抗体)-mediated degradation of CDC25C is associated with lysine-48-linked CDC25C polyubiquitination driven by the TRIB2 (显示 TRIB2 抗体) kinase-like domain.
the biology of the activation/deactivation of CDC25 (显示 RASGRF1 抗体) by kinases/phosphatases to maintain the level of CDK (显示 CDK4 抗体)-cyclin (显示 PCNA 抗体) activities and thus the genomic stability
the knockdown of CDC25C can reduce both the radiotherapy sensitivity and the proliferation activity of EC9706 cells.
results identify CDC25C as a downstream target of the mutated tyrosine kinase (显示 TXK 抗体) FLT3 (显示 FLT3 抗体)-ITD affecting cell-cycle regulation in a model of AML (显示 RUNX1 抗体)
Suggest that the p53 (显示 TP53 抗体)-p21 (显示 CDKN1A 抗体)-DREAM-CDE/CHR pathway regulates p53 (显示 TP53 抗体)-dependent repression of Survivin (显示 BIRC5 抗体), CDC25C, and PLK1 (显示 PLK1 抗体) in HCT116 cells.
Data indicate that nine compounds were identified with Ki values for CDC25A, -B and -C ranging from 0.01 to 4.4 muM.
oxidative stress-induced (显示 SQSTM1 抗体) DNA damage of mouse zygotes triggers the cell cycle checkpoint, which results in G2/M cell cycle arrest, and that phospho-Cdc25B (显示 CDC25B 抗体) (Ser323), phospho-Cdc25C (Ser216), and phospho-Cdc2 (显示 CDK1 抗体) (Tyr15) participate in activating the G2/M checkpoint.
The role of Cdc25c and Cdc25b (显示 CDC25B 抗体) in activating G2/M cell cycle checkpoint in zygote.
an asymmetrical distribution pattern for Cdc25c transcripts in 2-cell embryos.
CDC25A (显示 CDC25A 抗体) and CDC25B (显示 CDC25B 抗体) but not CDC25C compensate for each other to maintain the proliferative capacity of intestinal epithelial stem and progenitor cells
A single cell cycle genes homology region controls transcription of the cdc25C gene and is able to cooperate with E2F (显示 E2F1 抗体) or Sp1 (显示 SP1 抗体)/3 sites
Cdc25A (显示 CDC25A 抗体), or possibly other phosphatases, is able to functionally compensate for the loss of Cdc25B (显示 CDC25B 抗体) and Cdc25C in mice
The present study was aimed to investigate the possibility that selenium (Se)-induced oxidative stress mediated alterations in Cdc25c and p21 (显示 D4S234E 抗体) may cause modulations in the CDC2 (显示 CDK1 抗体)/Cyclin B1 (显示 CCNB1 抗体) complex responsible for G2/M phase checkpoint in spermatogenesis.
In Lzts1 (显示 LZTS1 抗体)(-/-) mouse embryo fibroblasts (MEFs), Cdc25C degradation was increased during M phase, resulting in decreased Cdk1 (显示 CDK1 抗体) activity.
PP2A:B56delta as a key upstream regulator of Cdk1 (显示 CDK1 抗体) activity upon exit from mitosis
Blocking mitotic entry by adding the catalytic subunit of protein kinase A results in increased wee1 Ser549 phosphorylation and maintenance of cdc25C.
These observations identify PP2A (显示 PPP2R2B 抗体)/B56delta as a central checkpoint effector and suggest a mechanism for controlling 14-3-3 (显示 YWHAQ 抗体) interactions to promote mitosis.
In Xenopus oocytes, p42 MAPK (显示 MAPK1 抗体) interacts with hypophosphorylated Cdc25 before meiotic induction. During meiotic induction, p42 MAPK (显示 MAPK1 抗体) phosphorylates Cdc25 at three sites, increasing Cdc25's phosphatase activity.
This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
cell division cycle 25 homolog C (S. pombe)
, m-phase inducer phosphatase 3-like
, cell division cycle 25 homolog C
, cell division cycle 25C
, Dual specificity phosphatase Cdc25C
, M-phase inducer phosphatase 3
, dual specificity phosphatase Cdc25C
, dual specificity phosphatase CDC25C
, mitosis inducer CDC25
, phosphotyrosine phosphatase
, protein phosphatase 1, regulatory subunit 60
, cell cycle phosphatase CDC25C
, cell division cycle control protein 25C