anti-CDC25C (CDC25C) 抗体产品概述

Full name:
anti-Cell Division Cycle 25 Homolog C (S. Pombe) 抗体 (CDC25C)
在www.antibodies-online.cn可供290 Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C) 抗体的26不同的供货商。 再加上,我们可以发CDC25C 蛋白 (8)CDC25C 试剂盒 (2)和数多这个蛋白质的别的产品。 总共313 CDC25C产品已列进来了。
别名:
Cdc25, cdc25-3, CDC25C, PPP1R60, xcdc25-3, xcdc25c
列出全部抗体 基因 基因ID UniProt
CDC25C 995 P30307
CDC25C 12532 P48967
CDC25C 307511  

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引用最多的anti-CDC25C 抗体

  1. Human Monoclonal CDC25C Primary Antibody for WB - ABIN393664 : Olson, Wang, Pankratz, Fredericksen, Vachon, Vierkant, Cerhan, Couch: Centrosome-related genes, genetic variation, and risk of breast cancer. in Breast cancer research and treatment 2010 (PubMed)
    Show all 5 references for 393664

  2. Human Monoclonal CDC25C Primary Antibody for BI, WB - ABIN967552 : Peng, Graves, Thoma, Wu, Shaw, Piwnica-Worms: Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. in Science (New York, N.Y.) 1997 (PubMed)
    Show all 5 references for 967552

  3. Human Polyclonal CDC25C Primary Antibody for IF, IHC (p) - ABIN196818 : Toyoshima-Morimoto, Taniguchi, Nishida: Plk1 promotes nuclear translocation of human Cdc25C during prophase. in EMBO reports 2002 (PubMed)
    Show all 4 references for 196818

  4. Human Polyclonal CDC25C Primary Antibody for IF, IHC (p) - ABIN197346 : Ferguson, White, Donovan, Piwnica-Worms: Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases. in Molecular and cellular biology 2005 (PubMed)
    Show all 3 references for 197346

  5. Human Polyclonal CDC25C Primary Antibody for EIA, WB - ABIN360223 : Varmeh, Manfredi: Overexpression of the dual specificity phosphatase, Cdc25C, confers sensitivity on tumor cells to doxorubicin-induced cell death. in Molecular cancer therapeutics 2008 (PubMed)
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  6. Human Monoclonal CDC25C Primary Antibody for WB - ABIN659132 : Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: A Large-scale genetic association study of esophageal adenocarcinoma risk. in Carcinogenesis 2010 (PubMed)
    Show all 2 references for 659132

  7. Human Polyclonal CDC25C Primary Antibody for IF (p), IHC (p) - ABIN1387108 : Ghate, Chaudhuri, Sarkar, Sajem, Panja, Rout, Mandal: An antioxidant extract of tropical lichen, Parmotrema reticulatum, induces cell cycle arrest and apoptosis in breast carcinoma cell line MCF-7. in PLoS ONE 2013 (PubMed)
    Show all 2 references for 1387108

  8. Human Polyclonal CDC25C Primary Antibody for IF (p), IHC (p) - ABIN746993 : Yin, Jiang, Peng, Cui, Zhou, He, Zuo, Ouyang, Fan, Fang: The molecular mechanism of G2M cell cycle arrest induced by AFB1 in the jejunum. in Oncotarget 2016 (PubMed)
    Show all 2 references for 746993

  9. Human Polyclonal CDC25C Primary Antibody for WB - ABIN2792164 : Bonnet, Mayonove, Morris: Differential phosphorylation of Cdc25C phosphatase in mitosis. in Biochemical and biophysical research communications 2008 (PubMed)

更多抗CDC25C的相互作用对抗体

Human Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C) interaction partners

  1. Myelodysplastic syndrome -related P95 (显示 NBN 抗体) point mutants of SRSF2 (显示 SRSF2 抗体) lead to alternative splicing of CDC25C in a manner that is not dependent on the DNA damage response.

  2. The aim of this review is to shed light on the role of four different phosphatases (PTEN (显示 PTEN 抗体), PP2A (显示 PPP2R4 抗体), CDC25 (显示 RASGRF1 抗体) and DUSP1 (显示 DUSP1 抗体)) in five different solid tumors (breast cancer, lung cancer, pancreatic cancer, prostate cancer and ovarian cancer), in order to better understand the most frequent and aggressive primary cancer of the central nervous system, glioblastoma.

  3. Data show that TRIB2 (显示 TRIB2 抗体)-mediated degradation of CDC25C is associated with lysine-48-linked CDC25C polyubiquitination driven by the TRIB2 (显示 TRIB2 抗体) kinase-like domain.

  4. the biology of the activation/deactivation of CDC25 (显示 RASGRF1 抗体) by kinases/phosphatases to maintain the level of CDK (显示 CDK4 抗体)-cyclin (显示 PCNA 抗体) activities and thus the genomic stability

  5. the knockdown of CDC25C can reduce both the radiotherapy sensitivity and the proliferation activity of EC9706 cells.

  6. results identify CDC25C as a downstream target of the mutated tyrosine kinase (显示 TXK 抗体) FLT3 (显示 FLT3 抗体)-ITD affecting cell-cycle regulation in a model of AML (显示 RUNX1 抗体)

  7. Suggest that the p53 (显示 TP53 抗体)-p21 (显示 CDKN1A 抗体)-DREAM-CDE/CHR pathway regulates p53 (显示 TP53 抗体)-dependent repression of Survivin (显示 BIRC5 抗体), CDC25C, and PLK1 (显示 PLK1 抗体) in HCT116 cells.

  8. Data indicate that nine compounds were identified with Ki values for CDC25A, -B and -C ranging from 0.01 to 4.4 muM.

  9. These miR (显示 MLXIP 抗体)-142-3p functioned as a tumor suppressor by targeting CDC25C.

  10. Cdc25C negatively regulates proapoptotic ASK1 (显示 MAP3K5 抗体) in a cell cycle-dependent manner and may play a role in G2/M checkpoint-mediated apoptosis.

Mouse (Murine) Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C) interaction partners

  1. oxidative stress-induced (显示 SQSTM1 抗体) DNA damage of mouse zygotes triggers the cell cycle checkpoint, which results in G2/M cell cycle arrest, and that phospho-Cdc25B (显示 CDC25B 抗体) (Ser323), phospho-Cdc25C (Ser216), and phospho-Cdc2 (显示 CDK1 抗体) (Tyr15) participate in activating the G2/M checkpoint.

  2. The role of Cdc25c and Cdc25b (显示 CDC25B 抗体) in activating G2/M cell cycle checkpoint in zygote.

  3. an asymmetrical distribution pattern for Cdc25c transcripts in 2-cell embryos.

  4. CDC25A (显示 CDC25A 抗体) and CDC25B (显示 CDC25B 抗体) but not CDC25C compensate for each other to maintain the proliferative capacity of intestinal epithelial stem and progenitor cells

  5. A single cell cycle genes homology region controls transcription of the cdc25C gene and is able to cooperate with E2F (显示 E2F1 抗体) or Sp1 (显示 SP1 抗体)/3 sites

  6. Cdc25A (显示 CDC25A 抗体), or possibly other phosphatases, is able to functionally compensate for the loss of Cdc25B (显示 CDC25B 抗体) and Cdc25C in mice

  7. The present study was aimed to investigate the possibility that selenium (Se)-induced oxidative stress mediated alterations in Cdc25c and p21 (显示 D4S234E 抗体) may cause modulations in the CDC2 (显示 CDK1 抗体)/Cyclin B1 (显示 CCNB1 抗体) complex responsible for G2/M phase checkpoint in spermatogenesis.

  8. In Lzts1 (显示 LZTS1 抗体)(-/-) mouse embryo fibroblasts (MEFs), Cdc25C degradation was increased during M phase, resulting in decreased Cdk1 (显示 CDK1 抗体) activity.

  9. PP2A:B56delta as a key upstream regulator of Cdk1 (显示 CDK1 抗体) activity upon exit from mitosis

Xenopus laevis Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C) interaction partners

  1. Blocking mitotic entry by adding the catalytic subunit of protein kinase A results in increased wee1 Ser549 phosphorylation and maintenance of cdc25C.

  2. These observations identify PP2A (显示 PPP2R2B 抗体)/B56delta as a central checkpoint effector and suggest a mechanism for controlling 14-3-3 (显示 YWHAQ 抗体) interactions to promote mitosis.

  3. In Xenopus oocytes, p42 MAPK (显示 MAPK1 抗体) interacts with hypophosphorylated Cdc25 before meiotic induction. During meiotic induction, p42 MAPK (显示 MAPK1 抗体) phosphorylates Cdc25 at three sites, increasing Cdc25's phosphatase activity.

CDC25C 抗原简介

Antigen Summary

This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

Alternative names and synonyms associated with CDC25C

  • cell division cycle 25 homolog C (S. pombe) (CDC25C) 抗体
  • cell division cycle 25C (cdc25c) 抗体
  • cell division cycle 25C (LOC100343637) 抗体
  • cell division cycle 25C (CDC25C) 抗体
  • cell division cycle 25C (Cdc25c) 抗体
  • cell division cycle 25C (cdc25c-a) 抗体
  • Cdc25 抗体
  • cdc25-3 抗体
  • CDC25C 抗体
  • PPP1R60 抗体
  • xcdc25-3 抗体
  • xcdc25c 抗体

Protein level used designations for CDC25C

cell division cycle 25 homolog C (S. pombe) , m-phase inducer phosphatase 3-like , cell division cycle 25 homolog C , cell division cycle 25C , Dual specificity phosphatase Cdc25C , M-phase inducer phosphatase 3 , dual specificity phosphatase Cdc25C , dual specificity phosphatase CDC25C , mitosis inducer CDC25 , phosphotyrosine phosphatase , protein phosphatase 1, regulatory subunit 60 , cell cycle phosphatase CDC25C , cell division cycle control protein 25C

GENE ID SPECIES
714115 Macaca mulatta
100062352 Equus caballus
100451443 Pongo abelii
100124300 Xenopus (Silurana) tropicalis
100343637 Oryctolagus cuniculus
100588617 Nomascus leucogenys
610456 Canis lupus familiaris
507731 Bos taurus
100144474 Sus scrofa
995 Homo sapiens
12532 Mus musculus
307511 Rattus norvegicus
397737 Xenopus laevis
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