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Merlin 抗体

(Neurofibromin 2 (NF2))
This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development\; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq, Jul 2008].
Merlin 抗体  (AA 477-576) Merlin 抗体  (AA 477-576) Merlin 抗体 (AA 477-576) (ABIN6144548)

NF2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

Merlin 抗体  (AA 30-239) Merlin 抗体  (AA 30-239) Merlin 抗体 (AA 30-239) (ABIN7434395)

NF2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

Merlin 抗体  (AA 30-311) Merlin 抗体  (AA 30-311) Merlin 抗体 (AA 30-311) (ABIN7441928)

NF2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

Merlin 抗体 by Grade

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Merlin 抗体 by 适用

Find Merlin 抗体 for a variety of species such as anti-Human Merlin, anti-Rat Merlin, anti-Mouse Merlin. The species listed below are among those available. Click on a link to go to the corresponding products.

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Merlin 抗体 by 抗原表位

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Merlin 抗体 by 克隆形成能力

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Merlin 抗体 by 克隆

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Merlin 抗体 by 标记

Find Merlin 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Merlin 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (6)
Cat. No. ABIN6144548
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7434395
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7441928
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7159413
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
Cat. No. ABIN7138643
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN1327740
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (3)
Cat. No. ABIN6256364
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IP
Validations
  • (4)
  • (2)
Cat. No. ABIN104130
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7260429
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6263224
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN6144550
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (1)
  • (2)
Cat. No. ABIN1532019
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (3)
Cat. No. ABIN390756
Quantity 400 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN2789402
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro)
Validations
  • (1)
Cat. No. ABIN685522
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our Merlin 抗体

Hu, Du, Shelton, Oldham, DiPersio, Klein: "An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice." in: Cell stem cell, Vol. 21, Issue 1, pp. 91-106.e6, (2018) (PubMed).

Vasilyeva, Murzina, Kireev, Pivovarov: "Influence of Membrane Receptor Lateral Diffusion on the Short-Term Depression of Acetylcholine-Induced Current in Helix Neurons." in: Cellular and molecular neurobiology, (2017) (PubMed).

Chen, Zhang, Xie, Wang, Cai, Choi, David, Huang, Yabuta, Nojima, Anders, Pan: "Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP." in: Genes & development, Vol. 29, Issue 12, pp. 1285-97, (2015) (PubMed).

Lavado, He, Paré, Neale, Olson, Giovannini, Cao: "Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators." in: Development (Cambridge, England), Vol. 140, Issue 16, pp. 3323-34, (2013) (PubMed).

Yu, Zeidel, Hill: "Cellular expression profile for interstitial cells of cajal in bladder - a cell often misidentified as myocyte or myofibroblast." in: PLoS ONE, Vol. 7, Issue 11, pp. e48897, (2012) (PubMed).

Angelo, Wu, Meng, Sun, Kopetz, McCutcheon, Slopis, Kurzrock: "Combining Curcumin (Diferuloylmethane) and Heat Shock Protein Inhibition for Neurofibromatosis 2 Treatment: Analysis of Response and Resistance Pathways." in: Molecular cancer therapeutics, (2011) (PubMed).

Zhang, Bai, David, Dong, Zheng, Cai, Giovannini, Liu, Anders, Pan: "The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals." in: Developmental cell, Vol. 19, Issue 1, pp. 27-38, (2010) (PubMed).

Lallemand, Saint-Amaux, Giovannini: "Tumor-suppression functions of merlin are independent of its role as an organizer of the actin cytoskeleton in Schwann cells." in: Journal of cell science, Vol. 122, Issue Pt 22, pp. 4141-9, (2010) (PubMed).

Wang, Lu, Tang, Wang, Wu: "The phosphorylation status of merlin in sporadic vestibular Schwannomas." in: Molecular and cellular biochemistry, Vol. 324, Issue 1-2, pp. 201-6, (2009) (PubMed).

Yang, Hinds: "Phosphorylation of ezrin by cyclin-dependent kinase 5 induces the release of Rho GDP dissociation inhibitor to inhibit Rac1 activity in senescent cells." in: Cancer research, Vol. 66, Issue 5, pp. 2708-15, (2006) (PubMed).

Aliases for Merlin 抗体

neurofibromin 2 (NF2) 抗体
neurofibromin 2 (Nf2) 抗体
neurofibromin 2a (merlin) (nf2a) 抗体
neurofibromin 2b (merlin) (nf2b) 抗体
neurofibromin 2 (merlin) S homeolog (nf2.S) 抗体
ACN 抗体
BANF 抗体
merlin 抗体
NF2 抗体
nf2 抗体
NF2a 抗体
SCH 抗体
zgc:194620 抗体
zgc:194631 抗体
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