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anti-Neurofibromin 2 (NF2) 抗体产品概述

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anti-Neurofibromin 2 抗体 (NF2)
在www.antibodies-online.cn可供162 Neurofibromin 2 (NF2) 抗体的24不同的供货商。 再加上,我们可以发Neurofibromin 2 试剂盒 (15)Neurofibromin 2 蛋白 (7)和数多这个蛋白质的别的产品。 总共196 Neurofibromin 2产品已列进来了。
别名:
ACN, BANF, merlin, NF2, NF2a, SCH, zgc:194620, zgc:194631

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引用最多的anti-Neurofibromin 2 抗体

  1. Human Polyclonal NF2 Primary Antibody for IHC (p), WB - ABIN197520 : Xiao, Gallagher, Shetler, Skele, Altomare, Pestell, Jhanwar, Testa: The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression. in Molecular and cellular biology 2005 (PubMed)
    Show all 4 references for ABIN197520

  2. Human Polyclonal NF2 Primary Antibody for IF, WB - ABIN197028 : Yang, Hinds: Phosphorylation of ezrin by cyclin-dependent kinase 5 induces the release of Rho GDP dissociation inhibitor to inhibit Rac1 activity in senescent cells. in Cancer research 2006 (PubMed)
    Show all 4 references for ABIN197028

  3. Human Polyclonal NF2 Primary Antibody for IHC, ELISA - ABIN1532019 : Yu, Zeidel, Hill: Cellular expression profile for interstitial cells of cajal in bladder - a cell often misidentified as myocyte or myofibroblast. in PLoS ONE 2012 (PubMed)
    Show all 3 references for ABIN1532019

  4. Human Polyclonal NF2 Primary Antibody for EIA, WB - ABIN117953 : Gutmann, Wright, Geist, Snider: Expression of the neurofibromatosis 2 (NF2) gene isoforms during rat embryonic development. in Human molecular genetics 1995 (PubMed)
    Show all 2 references for ABIN117953

  5. Human Polyclonal NF2 Primary Antibody for IP, IHC - ABIN104130 : Wang, Lu, Tang, Wang, Wu: The phosphorylation status of merlin in sporadic vestibular Schwannomas. in Molecular and cellular biochemistry 2009 (PubMed)
    Show all 2 references for ABIN104130

  6. Human Polyclonal NF2 Primary Antibody for ELISA, WB - ABIN1533058 : Trofatter, MacCollin, Rutter, Murrell, Duyao, Parry, Eldridge, Kley, Menon, Pulaski: A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor. in Cell 1993 (PubMed)
    Show all 2 references for ABIN1533058

  7. Zebrafish (Danio rerio) Polyclonal NF2 Primary Antibody for EIA, IHC (p) - ABIN401528 : Sadler, Amsterdam, Soroka, Boyer, Hopkins: A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease. in Development (Cambridge, England) 2005 (PubMed)

  8. Human Polyclonal NF2 Primary Antibody for EIA, WB - ABIN453191 : James, Han, Polizzano, Plotkin, Manning, Stemmer-Rachamimov, Gusella, Ramesh: NF2/merlin is a novel negative regulator of mTOR complex 1, and activation of mTORC1 is associated with meningioma and schwannoma growth. in Molecular and cellular biology 2009 (PubMed)

更多抗Neurofibromin 2的相互作用对抗体

Zebrafish Neurofibromin 2 (NF2) interaction partners

  1. Mutation of nf2 gene develops extrahepatic choledochal cysts in the common bile duct

Mouse (Murine) Neurofibromin 2 (NF2) interaction partners

  1. co-deletion of Rac1 with Nf2 blocks tumor initiation but paradoxically exacerbates hepatomegaly induced by Nf2 loss, which can be suppressed either by treatment with pro-oxidants or by co-deletion of Yap (显示 YAP1 抗体).

  2. Merlin controls the repair capacity of Schwann cells after injury by regulating Hippo/YAP (显示 YAP1 抗体) signaling activity.

  3. NF2 is activated by oxidative stress in cardiomyocytes and myocardium and facilitates apoptosis.

  4. loss of axonal contact following nerve injury results in merlin phosphorylation leading to increased p75(NTR (显示 NGFR 抗体)) expression.

  5. Loss of Nf2 and Cdkn2a (显示 CDKN2A 抗体)/b have synergistic effects with PDGF-B (显示 PDGFB 抗体) overexpression promoting meningioma malignant transformation.

  6. Merlin 1 and 2 act as tumor suppressors and are required for optimal sperm maturation

  7. Together our results uncover miRNAs as yet another negative mechanism controlling Merlin tumor suppressor functions.

  8. Merlin and Ezrin (显示 EZR 抗体) are components of a mechanism where mechanical forces associated with cell junctions are transduced across the cell cortex via cortical actomyosin cytoskeleton to control lateral mobility and activity of epidermal growth factor receptor (显示 EGFR 抗体).

  9. The study describe a novel NF2 mouse model recapitulating schwannoma phenotypes found in human patients where tumors develop in the cranial nerve VIII (显示 COX8A 抗体) and/or the spinal roots.

  10. Nf2/Merlin controls spinal cord neural progenitor function in a Rac1/ErbB2 (显示 ERBB2 抗体)-dependent manner.

Human Neurofibromin 2 (NF2) interaction partners

  1. co-deletion of Rac1 with Nf2 blocks tumor initiation but paradoxically exacerbates hepatomegaly induced by Nf2 loss, which can be suppressed either by treatment with pro-oxidants or by co-deletion of Yap (显示 YAP1 抗体).

  2. Data suggest that, at least using the commercial antibodies used in this study, immunohistochemical staining for NF2 (neurofibromin 2), LATS2 (显示 LATS2 抗体) (large tumor suppressor (显示 LATS1 抗体) kinase 2), and YAP (显示 YAP1 抗体)/TAZ (显示 TAZ 抗体) (nuclear translocation of complex of Yes-associated protein [YAP (显示 YAP1 抗体)] with transcriptional coactivator with PDZ-binding motif (显示 WWTR1 抗体) [TAZ (显示 TAZ 抗体)]) is not helpful for differential diagnosis of mesothelioma versus a benign proliferation.

  3. The mortality of patients with NF2 diagnosed in more recent decades was lower than that of patients diagnosed earlier.

  4. AMOTL1 (显示 AMOTL1 抗体) Promotes Breast Cancer Progression and Is Antagonized by Merlin

  5. homozygous deletions in CDKN2A (显示 CDKN2A 抗体) and hemizygous loss of NF2 as detected by fluorescence in situ hybridization would confer a poor clinical outcome and may guide future treatment decisions for patients with peritoneal mesothelioma.

  6. NF2/merlin inactivation augments mutant RAS signaling by promoting YAP (显示 YAP1 抗体)/TEAD-driven transcription of oncogenic and wild-type RAS, resulting in greater MAPK (显示 MAPK1 抗体) output and increased sensitivity to MEK (显示 MAP2K1 抗体) inhibitors.

  7. Loss of Nf2 and Cdkn2a (显示 CDKN2A 抗体)/b have synergistic effects with PDGF-B (显示 PDGFB 抗体) overexpression promoting meningioma malignant transformation.

  8. we demonstrate that NF2 negatively controls the invasiveness of Glioblastoma multiforme through YAP (显示 YAP1 抗体)-dependent induction of CYR61/CCN1 (显示 CYR61 抗体) and miR (显示 MLXIP 抗体)-296-3p.

  9. angiomotin and Merlin respectively interface cortical actin filaments and core kinases in Hippo signaling

  10. (Delta2-4)Merlin variant disrupts the normal function of Merlin and promotes hepatocellular carcinoma metastasis.

Neurofibromin 2 (NF2) 抗原简介

Antigen Summary

This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development\; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.

Alternative names and synonyms associated with Neurofibromin 2 (NF2)

  • neurofibromin 2b (merlin) (nf2b) 抗体
  • neurofibromin 2 (bilateral acoustic neuroma) (NF2) 抗体
  • neurofibromin 2 (merlin) (NF2) 抗体
  • neurofibromin 2 (NF2) 抗体
  • neurofibromin 2 (LOC100357691) 抗体
  • merlin-like (LOC417537) 抗体
  • neurofibromatosis 2 (Nf2) 抗体
  • neurofibromin 2 (merlin) (Nf2) 抗体
  • neurofibromin 2a (merlin) (nf2a) 抗体
  • ACN 抗体
  • BANF 抗体
  • merlin 抗体
  • NF2 抗体
  • NF2a 抗体
  • SCH 抗体
  • zgc:194620 抗体
  • zgc:194631 抗体

Protein level used designations for anti-Neurofibromin 2 (NF2) 抗体

neurofibromin 2 (bilateral acoustic neuroma) , merlin , neurofibromatosis 2 , neurofibromin 2 , moesin-ezrin-radixin-like protein , neurofibromin-2 , schwannomin , moesin-ezrin-radixin like , moesin-ezrin-radizin-like protein , schwannomerlin

GENE ID SPECIES
405887 Danio rerio
395158 Gallus gallus
100058977 Equus caballus
100329097 Saccoglossus kowalevskii
100357691 Oryctolagus cuniculus
417537 Gallus gallus
18016 Mus musculus
4771 Homo sapiens
25744 Rattus norvegicus
477535 Canis lupus familiaris
100520699 Sus scrofa
540479 Bos taurus
561184 Danio rerio
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