anti-LIMS2 (LIMS2) 抗体产品概述

Full name:
anti-LIM and Senescent Cell Antigen-Like Domains 2 抗体 (LIMS2)
在www.antibodies-online.cn可供71 LIM and Senescent Cell Antigen-Like Domains 2 (LIMS2) 抗体的12不同的供货商。 再加上,我们可以发LIMS2 蛋白 (3)和数多这个蛋白质的别的产品。 总共79 LIMS2产品已列进来了。
别名:
LIMS1, PINCH-2, PINCH2

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引用最多的anti-LIMS2 抗体

  1. Mouse (Murine) Polyclonal LIMS2 Primary Antibody for WB - ABIN657520 : Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: New genetic associations detected in a host response study to hepatitis B vaccine. in Genes and immunity 2010 (PubMed)
    Show all 3 references for 657520

更多抗LIMS2的相互作用对抗体

Mouse (Murine) LIM and Senescent Cell Antigen-Like Domains 2 (LIMS2) interaction partners

  1. Let-7g controls the motility of mouse myoblasts in cell culture by post-transcriptionally regulating the expression of Pinch-2.

  2. Rsu-1 (显示 RSU1 抗体) expression is dramatically decreased in PINCH (显示 LIMS1 抗体) double knockout mouse livers.

  3. LIM1 (显示 LHX1 抗体) domain only of either PINCH1 (显示 LIMS1 抗体) or PINCH2 can prevent ILK (显示 ILK 抗体) degradation despite their failure to localize to focal adhesions.

  4. Absence of either PINCH1 (显示 LIMS1 抗体) or PINCH2 in myocardium leads to exacerbated cardiac injury and deterioration in cardiac function after myocardial infarction.

Human LIM and Senescent Cell Antigen-Like Domains 2 (LIMS2) interaction partners

  1. Mammalian cells have two functional PINCH (显示 LIMS1 抗体) proteins, PINCH1 (显示 LIMS1 抗体) and PINCH2. PINCH (显示 LIMS1 抗体) not only binds to Nck2 (显示 NCK2 抗体) and engages in the signaling of growth factor receptors, but also forms a ternary complex with ILK (显示 ILK 抗体) and parvin (显示 PARVA 抗体) (IPP (显示 IPP 抗体) complex).

  2. Data indicate compound heterozygous missense mutations that are predicted to be pathogenic in LIM and senescent cell antigen-like domains 2 protein (LIMS2).

  3. Results defined the functional role of copy number variations involving PINCH-2 in cancer progression based on the field cancerization effect; cell migration and invasion through autocrine and paracrine function as part of the field cancerization effect.

  4. PINCH-2 mRNA is overexpressed in malignant mesothelioma

  5. These results identify a novel nuclear and focal adhesion protein that associates with ILK (显示 ILK 抗体) and reveals an important role of PINCH-2 in the regulation of the PINCH-1 (显示 LIMS1 抗体)-ILK (显示 ILK 抗体) interaction, cell shape change, and migration.

  6. LIMS2 may be useful as a molecular biomarker and a therapeutic target by increasing its expression and activity in gastric cancer

LIMS2 抗原简介

Antigen Summary

This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase), a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain forming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with LIMS2

  • LIM and senescent cell antigen like domains 2 (Lims2) 抗体
  • LIM and senescent cell antigen-like domains 2 (LIMS2) 抗体
  • LIMS1 抗体
  • PINCH-2 抗体
  • PINCH2 抗体

Protein level used designations for LIMS2

LIM and senescent cell antigen-like-containing domain protein 2 , PINCH-2 , particularly interesting new Cys-His protein 2 , ILK-binding protein , LIM-like protein 2 , LIM and senescent cell antigen-like domains 1

GENE ID SPECIES
225341 Mus musculus
55679 Homo sapiens
515401 Bos taurus
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