Junction Plakoglobin (JUP) ELISA试剂盒产品概述

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Junction Plakoglobin ELISA试剂盒 (JUP)
在www.antibodies-online.cn可供16 Junction Plakoglobin (JUP) ELISA试剂盒的10不同的供货商。 再加上,我们可以发Junction Plakoglobin 抗体 (344)Junction Plakoglobin 蛋白 (5)和数多这个蛋白质的别的产品。 总共374 Junction Plakoglobin产品已列进来了。
别名:
ARVD12, cb80, CTNNG, D930025P04Rik, danPG, DP3, DPIII, fb11b06, jup, PDGB, PG, PKGB, plak, wu:fb11b06

引用最多的Junction Plakoglobin ELISA试剂盒

  1. Human JUP ELISA Kit for Sandwich ELISA - ABIN417915 : Ortega-Martínez, Gardeazabal, Erramuzpe, Sanchez-Diez, Cortés, García-Vázquez, Pérez-Yarza, Izu, Luís Díaz-Ramón, de la Fuente, Asumendi, Boyano: Vitronectin and dermcidin serum levels predict the metastatic progression of AJCC I-II early-stage melanoma. in International journal of cancer 2016 (PubMed)

适于 Junction Plakoglobin 相互作用对的更多 ELISA 试剂盒

Human Junction Plakoglobin (JUP) interaction partners

  1. Plakoglobin maintains the integrity of vascular endothelial cell junctions and regulates VEGF (显示 VEGFA ELISA试剂盒)-induced phosphorylation of VE-cadherin (显示 CDH5 ELISA试剂盒)

  2. In JUP mutations are the frequent cause of Arrhythmogenic cardiomyopathy, isolated Brugada syndrome can appear due to reduced sodium channel activities.

  3. investigated the in vitro tumor/metastasis suppressor effects of plakoglobin in ovarian cancer cell lines with mutant p53 expression and different cadherin profiles

  4. Reduced plakoglobin staining in intercalated discs of heart tissue from human arrhythmogenic right ventricular cardiomyopathy (ARVC) patients and in a murine ARVC model is caused by alterations in epitope accessibility and not by protein relocalization

  5. Idiopathic pulmonary fibrosis lung fibroblasts expressed less Pkgb protein than control fibroblasts, but characteristic fibroblast phenotypes (adhesion, proliferation, and apoptosis) were not controlled by Pkgb expression.

  6. Immunostaining for plakoglobin might serve as an additional diagnostic marker of arrhythmogenic right ventricular cardiomyopathy in forensic pathology.

  7. Expression of gamma-catenin in NSCLC cells resulted in reduced cell migration as determined by both scratch assays and trans-well cell migration assays.

  8. Six variants of uncertain clinical significance in the PKP2 (显示 PKP2 ELISA试剂盒), JUP, and DSG2 (显示 DSG2 ELISA试剂盒) genes showed a deleterious effect on mRNA splicing, indicating these are ARVD (显示 TGFB3 ELISA试剂盒)/C-related pathogenic splice site mutations.

  9. gamma-catenin is a tumor suppressor in esophageal squamous cell carcinoma and may serve as a prognostic marker

  10. Immunohistochemical analysis of plakoglobin had a relatively high sensitivity and specificity in arrhythmogenic right ventricular cardiomyopathy, but could not be relied upon as a diagnostic test for ARVC.

Mouse (Murine) Junction Plakoglobin (JUP) interaction partners

  1. Reduced plakoglobin staining in intercalated discs of heart tissue from human arrhythmogenic right ventricular cardiomyopathy (ARVC) patients and in a murine ARVC model is caused by alterations in epitope accessibility and not by protein relocalization

  2. Mice with hepatic loss of the desmosomal protein gamma-Catenin are prone to cholestatic injury and chemical carcinogenesis.

  3. EMMPRIN ensures proper actomyosin-driven maturation of competent endothelial junctions by forming a molecular complex with gamma-catenin (also known as junction plakoglobin) and Nm23 (also known as NME1), a nucleoside diphosphate kinase

  4. In 2 knockin mouse models, endogenous Jup was engineered to express the Naxos-associated form of plakoglobin. Insufficiency of the truncated Naxos plakoglobin, rather than gain of function, accounted for cardiac disease manifestations.

  5. plakoglobin (Pg) in conjunction with lymphoid enhancer-binding factor 1 (Lef-1 (显示 LEF1 ELISA试剂盒)) differentially regulates the proximal promoters of Dsc2 (显示 DSC2 ELISA试剂盒) and Dsc3 (显示 DSC3 ELISA试剂盒)

  6. our study reveals a function for gamma-catenin in the regulation of mESC differentiation and has implications for human cancers in which gamma-catenin is mutated and/or aberrantly expressed.

  7. The data suggest novel function(s) for plakoglobin (PG) beyond the heart and define a critical threshold of PG expression that is necessary for postnatal survival.

  8. decreased plakoglobin expression increases the invasive behavior of breast cancer cells; this is the first demonstration of a functional role for plakoglobin/gamma-catenin in the metastatic process

  9. The cadherin-catenin signaling pathway was inactivated in spinal motor neurons to assess the significance of motor neuron position in motor circuit assembly; genetic inactivation of both beta- and gamma-catenin or N-cadherin (显示 CDH2 ELISA试剂盒), disrupts motor neuron positioning.

  10. Lack of plakoglobin in epidermis leads to keratoderma.

Zebrafish Junction Plakoglobin (JUP) interaction partners

  1. Although plakoglobin is clearly present during normal odontogenesis, the loss of plakoglobin does not influence tooth development.

  2. plakoglobin localization in the heart region shifts from adherens junctions to desmosomes during heart chamber development

  3. knockdown of plakoglobin in zebrafish results in decreased heart size, reduced heartbeat, cardiac oedema, reflux of blood between heart chambers and a twisted (显示 POMT2 ELISA试剂盒) tail

Junction Plakoglobin (JUP) 抗原简介

Antigen Summary

This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene\; however, not all transcripts have been fully described.

Alternative names and synonyms associated with Junction Plakoglobin (JUP)

  • junction plakoglobin (jup) Elisa Kit
  • junction plakoglobin (Tsp_06656) Elisa Kit
  • junction plakoglobin (JUP) Elisa Kit
  • Junction plakoglobin (plak) Elisa Kit
  • junction plakoglobin (Jup) Elisa Kit
  • junction plakoglobin (jup-b) Elisa Kit
  • junction plakoglobin a (jupa) Elisa Kit
  • ARVD12 Elisa Kit
  • cb80 Elisa Kit
  • CTNNG Elisa Kit
  • D930025P04Rik Elisa Kit
  • danPG Elisa Kit
  • DP3 Elisa Kit
  • DPIII Elisa Kit
  • fb11b06 Elisa Kit
  • jup Elisa Kit
  • PDGB Elisa Kit
  • PG Elisa Kit
  • PKGB Elisa Kit
  • plak Elisa Kit
  • wu:fb11b06 Elisa Kit

Protein level used designations for JUP

desmoplakin 3 , junction plakoglobin , Junction plakoglobin , junction plakoglobin-like , plakoglobin , catenin (cadherin-associated protein), gamma 80kDa , desmoplakin III , desmoplakin-3 , gamma-catenin , gamma-catenin (plakoglobin) , gama-catenin

GENE ID SPECIES
395011 Xenopus (Silurana) tropicalis
398496 Xenopus laevis
10909874 Trichinella spiralis
100012969 Monodelphis domestica
100194931 Salmo salar
100345709 Oryctolagus cuniculus
100440279 Pongo abelii
100564925 Anolis carolinensis
429710 Gallus gallus
3728 Homo sapiens
445543 Bos taurus
16480 Mus musculus
81679 Rattus norvegicus
480522 Canis lupus familiaris
397592 Sus scrofa
399278 Xenopus laevis
30415 Danio rerio
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