anti-Angiomotin (AMOT) 抗体产品概述

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anti-Angiomotin 抗体 (AMOT)
在www.antibodies-online.cn可供98 Angiomotin (AMOT) 抗体的16不同的供货商。 再加上,我们可以发Angiomotin 试剂盒 (24)Angiomotin 蛋白 (5)和数多这个蛋白质的别的产品。 总共139 Angiomotin产品已列进来了。
别名:
AMOTL2, C81439, CAG-2, D0Kist1, E230009N18Rik, mKIAA1071, RGD1564027, si:dkey-13f9.6, Sii6, wu:fj21a07

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引用最多的anti-Angiomotin 抗体

  1. Human Polyclonal Angiomotin Primary Antibody for DB - ABIN1881054 : Heller, Adu-Gyamfi, Smith-Kinnaman, Babbey, Vora, Xue, Bittman, Stahelin, Wells: Amot recognizes a juxtanuclear endocytic recycling compartment via a novel lipid binding domain. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for 1881054

  2. Human Polyclonal Angiomotin Primary Antibody for WB - ABIN531071 : Chan, Lim, Chong, Pobbati, Huang, Hong: Hippo pathway-independent restriction of TAZ and YAP by angiomotin. in The Journal of biological chemistry 2011 (PubMed)
    Show all 2 references for 531071

  3. Human Polyclonal Angiomotin Primary Antibody for IF (p), IHC (p) - ABIN754873 : Shimada, Abe, Kohno, Satohisa, Konno, Takahashi, Hatakeyama, Arimoto, Kakuki, Kaneko, Takano, Saito, Kojima: Loss of tricellular tight junction protein LSR promotes cell invasion and migration via upregulation of TEAD1/AREG in human endometrial cancer. in Scientific reports 2017 (PubMed)

  4. Cow (Bovine) Polyclonal Angiomotin Primary Antibody for WB - ABIN2775938 : Holmgren, Ambrosino, Birot, Tullus, Veitonmäki, Levchenko, Carlson, Musiani, Iezzi, Curcio, Forni, Cavallo, Kiessling: A DNA vaccine targeting angiomotin inhibits angiogenesis and suppresses tumor growth. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

更多抗Angiomotin的相互作用对抗体

Cow (Bovine) Angiomotin (AMOT) interaction partners

  1. Amot and AmotL1 (显示 AMOTL1 抗体) have similar effects on endothelial migration and tight junction formation in vitro. In vivo Amot appears to control the cell polarity and AmotL1 (显示 AMOTL1 抗体) affects the stability of cell-cell junctions.

Zebrafish Angiomotin (AMOT) interaction partners

  1. Thus AMOT is a direct substrate of Lats1 (显示 LATS1 抗体)/2 mediating functions of the Hippo pathway in endothelial cell migration and angiogenesis.

  2. knockdown of Amot reduced the number of filopodia of endoth (显示 PDPN 抗体)elial tip cells and severely impaired the migration of intersegmental vessels

  3. Amot and AmotL1 (显示 AMOTL2 抗体) have similar effects on endothelial migration and tight junction formation in vitro. In vivo Amot appears to control the cell polarity and AmotL1 (显示 AMOTL2 抗体) affects the stability of cell-cell junctions.

Human Angiomotin (AMOT) interaction partners

  1. AMOT may function as an oncogene (显示 RAB1A 抗体) in the progression of colon cancer by activating the YAP (显示 YAP1 抗体)-ERK (显示 EPHB2 抗体)/PI3K (显示 PIK3CA 抗体)-AKT (显示 AKT1 抗体) signaling pathway.

  2. The lncRNA SNHG12 promotes cell proliferation and migration by upregulating AMOT gene expression in osteosarcoma cells in vivo and in vitro.

  3. angiomotin and Merlin respectively interface cortical actin filaments and core kinases in Hippo signaling

  4. Study shows miR (显示 MLXIP 抗体)-205 significantly downregulated and directly target the 3'-UTR (显示 UTS2R 抗体) of AMOT in breast cancer. In vitro, miR (显示 MLXIP 抗体)-205 regulates the proliferation and invasion of breast cancer cells through suppression of AMOT expression.

  5. Amot was highly expressed in breast cancer tissues and was important in the promotion of breast cancer cell proliferation and invasion. Amot knockdown in MCF-7 cells decreased the expression of YAP (显示 YAP1 抗体), YAP (显示 YAP1 抗体)/TAZ (显示 TAZ 抗体) and LATS1 (显示 LATS1 抗体).

  6. experiments indicate that AMOT and other motin family members function together with NEDD4L (显示 NEDD4L 抗体) to help complete immature virion assembly prior to ESCRT-mediated virus budding

  7. AMOT is a crucial suppressor of lung cancer metastasis and highlight its critical role as a tumor suppressor and its potential as a prognostic biomarker and therapeutic target for lung cancer.

  8. angiomotin proteins connect F-actin architecture to YAP (显示 YAP1 抗体) regulation.

  9. Scaffold proteins angiomotin (Amot) and angiomotin-related AmotL1 (显示 AMOTL1 抗体) and AmotL2 (显示 AMOTL2 抗体) were recently identified as negative regulators of YAP (显示 YAP1 抗体) and TAZ (显示 TAZ 抗体) by preventing their nuclear translocation.

  10. Within the nucleus, Amot-p130 (显示 RBL2 抗体) was associated with the transcriptional complex containing Yap (显示 YAP1 抗体) and Teads (TEA domain family members) and contributed to the regulation of a subset of Yap (显示 YAP1 抗体) target genes, many of which are associated with tumorigenesis.

Mouse (Murine) Angiomotin (AMOT) interaction partners

  1. a new function of RNF146 (显示 RNF146 抗体) and tankyrase in stabilizing the Crumbs complex through downregulation of AMOT proteins at the apical membrane, is reported.

  2. AMOT is a crucial suppressor of lung cancer metastasis and highlight its critical role as a tumor suppressor and its potential as a prognostic biomarker and therapeutic target for lung cancer.

  3. Within the nucleus, Amot-p130 was associated with the transcriptional complex containing Yap (显示 YAP1 抗体) and Teads (TEA domain family members) and contributed to the regulation of a subset of Yap (显示 YAP1 抗体) target genes, many of which are associated with tumorigenesis.

  4. The loss of Angiomotin, together with Angiomotin-like 2 (显示 AMOTL2 抗体), leads to differentiation of inner cell mass cells and compromised peri (显示 POSTN 抗体)-implantation development.

  5. The phosphorylation of S176 in the N-terminal domain of Amot is a critical step for activation of the Hippo pathway in adherens junctions and cell polarity disconnects the Hippo pathway from cell-cell adhesion by sequestering Amot from AJs.

  6. Amot, Amotl1 (显示 AMOTL1 抗体), and Amotl2 (显示 AMOTL2 抗体) are differentially expressed in uterine cells during the peri (显示 POSTN 抗体)-implantation period.

  7. A vaccine targeting angiomotin induces an antibody response which alters tumor vessel permeability and hampers the growth of established tumors.

  8. Depletion of Angiomotin in Nf2 (显示 NF2 抗体)(-/-) Schwann cells attenuates the Ras-MAPK (显示 MAPK1 抗体) signaling pathway, impedes cellular proliferation in vitro and tumorigenesis in vivo

  9. Angiomotin may promote neoplastic angiogenesis by both stimulating invasion as well as stabilizing established tubes.

  10. angiomotin, in addition to controlling cell motility, may play a role in the assembly of endothelial cell-cell junctions

Angiomotin (AMOT) 抗原简介

Antigen Summary

This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with Angiomotin (AMOT)

  • angiomotin (AMOT) 抗体
  • angiomotin like 2 (AMOTL2) 抗体
  • angiomotin (amot) 抗体
  • angiomotin (Amot) 抗体
  • AMOTL2 抗体
  • C81439 抗体
  • CAG-2 抗体
  • D0Kist1 抗体
  • E230009N18Rik 抗体
  • mKIAA1071 抗体
  • RGD1564027 抗体
  • si:dkey-13f9.6 抗体
  • Sii6 抗体
  • wu:fj21a07 抗体

Protein level used designations for anti-Angiomotin (AMOT) 抗体

angiomotin like 2 , angiomotin-like protein 2 , angiomotin-like protein 2-like , angiomotin p130 isoform , angiomotin p80 isoform

GENE ID SPECIES
100054069 Equus caballus
424863 Gallus gallus
485669 Canis lupus familiaris
538514 Bos taurus
563421 Danio rerio
100402195 Callithrix jacchus
422336 Gallus gallus
154796 Homo sapiens
481022 Canis lupus familiaris
27494 Mus musculus
300289 Rattus norvegicus
100158213 Sus scrofa
535509 Bos taurus
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