anti-小鼠 APP 抗体 for Western Blotting

Recommended APP Antibody (supplied by: Log in to see )

抗原
Amyloid beta (A4) Precursor Protein (APP) 抗体
  • AAA
  • ABETA
  • ABPP
  • AD1
  • APPI
  • CTFgamma
  • CVAP
  • PN-II
  • PN2
  • aaa
  • abeta
  • abpp
  • ad1
  • appi
  • ctfgamma
  • cvap
  • pn2
  • APP
  • APP-like
  • APPL
  • Abeta
  • BcDNA:GH04413
  • CG7727
  • Dmel\\CG7727
  • EG:65F1.5
  • appl
  • Abpp
  • Adap
  • Ag
  • Cvap
  • E030013M08Rik
  • betaApp
  • app
  • wu:fj34d10
  • wu:fk65e12
  • zgc:85740
  • amyloid beta precursor protein
  • amyloid beta (A4) precursor protein
  • beta amyloid protein precursor-like
  • amyloid beta (A4) precursor protein a
  • amyloid beta precursor protein L homeolog
  • APP
  • app
  • Appl
  • App
  • appa
  • app.L
抗原表位
Middle Region
107
106
71
39
37
32
30
19
17
15
15
14
14
13
12
10
9
7
7
7
7
6
6
5
5
5
5
5
5
5
5
5
5
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠
938
385
364
39
27
20
18
18
14
13
11
10
7
7
4
4
4
3
2
2
1
宿主

652
263
52
6
2
克隆类型
多克隆
标记
This APP antibody is un-conjugated
51
43
41
17
16
14
14
14
13
13
13
13
13
13
13
8
8
4
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
668
403
293
164
159
121
87
57
40
35
17
15
15
10
8
3
3
2
1
1
1
选项
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产品编号 ABIN2777739
$ 289.00
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.0849469 ABIN2777738 WB Rabbit Middle Region Log in to see Polyclonal 1
3.0849469 ABIN2779739 IHC WB Rabbit C-Term Log in to see Polyclonal
3.0849469 ABIN2787850 WB Rabbit C-Term Log in to see Polyclonal
3.0849469 ABIN3043787 IHC (p) WB Rabbit IgG AA 672-713, C-Term Log in to see Polyclonal 4
3.0849469 ABIN358841 EIA WB Rabbit Ig N-Term Log in to see Polyclonal 5
3.0849469 ABIN1449275 WB Mouse IgG1 AA 18-38 Log in to see 3-00E-009 3
3.0849469 ABIN2465038 ELISA WB Goat N-Term Log in to see Polyclonal
3.0849469 ABIN317496 EIA IHC (p) WB Mouse IgG2b AA 18-289 Log in to see J4H9
3.0849469 ABIN1532190 IF IHC ELISA WB Rabbit IgG AA 711-760 Log in to see Polyclonal
3.0849469 ABIN1531173 IF IHC ELISA WB Rabbit IgG AA 711-760, pThr743 Log in to see Polyclonal
3.0849469 ABIN2451919 IC IF WB Rabbit N-Term, AA 18-38 Log in to see Polyclonal 4
3.0849469 ABIN2451920 IC IF IHC WB Rabbit C-Term, AA 671-695 Log in to see Polyclonal 5
3.0849469 ABIN2477428 IHC (p) WB Rabbit IgG AA 672-681 Log in to see Polyclonal 3
3.0849469 ABIN1742281 ICC IHC WB Rabbit C-Term Log in to see Polyclonal 1
3.0849469 ABIN2464967 ELISA WB Goat N-Term Log in to see Polyclonal
3.0849469 ABIN1077787 ICC IHC IP WB Rabbit IgG AA 18-286 Log in to see Polyclonal
3.0849469 ABIN1858064 ICC IHC IP WB Rabbit IgG AA 672-770 Log in to see Polyclonal
3.0849469 ABIN306462 ELISA WB Mouse IgG2b, kappa chain Log in to see J4H0 1
3.0849469 ABIN2855011 ICC IF IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
3.0849469 ABIN1869978 IHC WB Rabbit IgG pThr743 Log in to see Polyclonal

General

抗原 Amyloid beta (A4) Precursor Protein (APP) 抗体
抗原表位 Middle Region
(107), (106), (71), (39), (37), (32), (30), (19), (17), (15), (15), (14), (14), (13), (12), (10), (9), (7), (7), (7), (7), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用 牛, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠
(938), (385), (364), (39), (27), (20), (18), (18), (14), (13), (11), (10), (7), (7), (4), (4), (4), (3), (2), (2), (1)
宿主
(652), (263), (52), (6), (2)
克隆类型
多克隆
标记 This APP antibody is un-conjugated
(51), (43), (41), (17), (16), (14), (14), (14), (13), (13), (13), (13), (13), (13), (13), (8), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Immunohistochemistry (IHC), Western Blotting (WB)
(668), (403), (293), (164), (159), (121), (87), (57), (40), (35), (17), (15), (15), (10), (8), (3), (3), (2), (1), (1), (1)
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APP抗体详情

APP目标详情 使用细节 贮存及处理 References for anti-APP antibody (ABIN2777739) 图像
Blocking Peptide Blocking peptide for this product available: ABIN973340
序列 RMNQSLSLLY NVPAVAEEIQ DEVDELLQKE QNYSDDVLAN MISEPRISYG
预测反应 Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
产品特性 This is a rabbit polyclonal antibody against APP. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
免疫原 The immunogen is a synthetic peptide directed towards the middle region of human APP

APP目标详情

APP抗体详情 使用细节 贮存及处理 References for anti-APP antibody (ABIN2777739) 图像 回页首
抗原
别名 APP (APP Antibody 摘要)
背景 APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
Alias Symbols: AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN2, PN-II
Protein Size: 770
分子量 85 kDa
基因ID 351
NCBI登录号 NM_000484, NP_000475
UniProt P05067
研究领域 Signaling
途径 Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour

使用细节

APP抗体详情 APP目标详情 贮存及处理 References for anti-APP antibody (ABIN2777739) 图像 回页首
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 770 AA

限制 仅限研究用

贮存及处理

APP抗体详情 APP目标详情 使用细节 References for anti-APP antibody (ABIN2777739) 图像 回页首
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-APP antibody (ABIN2777739)

APP抗体详情 APP目标详情 使用细节 贮存及处理 图像 回页首
背景

Locascio, Fukumoto, Yap, Bottiglieri, Growdon, Hyman, Irizarry: "Plasma amyloid beta-protein and C-reactive protein in relation to the rate of progression of Alzheimer disease." in: Archives of neurology, Vol. 65, Issue 6, pp. 776-85, 2008

图像

APP抗体详情 APP目标详情 使用细节 贮存及处理 References for anti-APP antibody (ABIN2777739) 回页首
厂商提供的图像
Immunohistochemistry (IHC) image for anti-Amyloid beta (A4) Precursor Protein (APP) (Middle Region) antibody (ABIN2777739) Sample Type : Mouse hippo campus Primary Antibody Dilution : 1:100 Secondary Antib...
Western Blotting (WB) image for anti-Amyloid beta (A4) Precursor Protein (APP) (Middle Region) antibody (ABIN2777739) WB Suggested Anti-APP Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:2500 Positive Co...