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MSK1 ELISA试剂盒

(Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5))
Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes to RELA inhibition and repression of inflammatory gene expression. In skeletal myoblasts is required for phosphorylation of RELA at 'Ser-276' during oxidative stress. In erythropoietin-stimulated cells, is necessary for the 'Ser-727' phosphorylation of STAT3 and regulation of its transcriptional potential. Phosphorylates ETV1/ER81 at 'Ser-191' and 'Ser-216', and thereby regulates its ability to stimulate transcription, which may be important during development and breast tumor formation. Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A. Phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and EGF, which results in the transcriptional activation of several immediate early genes, including proto- oncogenes c-fos/FOS and c-jun/JUN. May also phosphorylate 'Ser-28' of histone H3. Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 1 (HMGN1/HMG14). In lipopolysaccharide-stimulated primary macrophages, acts downstream of the Toll-like receptor TLR4 to limit the production of pro- inflammatory cytokines. Functions probably by inducing transcription of the MAP kinase phosphatase DUSP1 and the anti- inflammatory cytokine interleukin 10 (IL10), via CREB1 and ATF1 transcription factors. Plays a role in neuronal cell death by mediating the downstream effects of excitotoxic injury.
MSK1 ELISA 试剂盒 (ABIN1380308)

RPS6KA5 适用: 人, 小鼠 pThr581 Colorimetric Cell ELISA Cell Culture Cells

MSK1 ELISA 试剂盒 (ABIN1380780)

RPS6KA5 适用: 人, 小鼠 pSer212 Colorimetric Cell ELISA Cell Culture Cells

MSK1 ELISA 试剂盒 (ABIN1380644)

RPS6KA5 适用: 人, 小鼠 pSer376 Colorimetric Cell ELISA Cell Culture Cells

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Find MSK1 ELISA试剂盒 for a variety of species such as anti-Human MSK1, anti-Mouse MSK1. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular MSK1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
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Validations
Cat. No. ABIN1380308
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380780
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380644
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
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Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4886213
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6205785
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Cell ELISA
Validations
Cat. No. ABIN5526698
Quantity 96 tests
Datasheet Datasheet

Aliases for MSK1 ELISA试剂盒

ribosomal protein S6 kinase A5 (RPS6KA5) ELISA试剂盒
ribosomal protein S6 kinase, polypeptide 5 (Rps6ka5) ELISA试剂盒
ribosomal protein S6 kinase A5 (Rps6ka5) ELISA试剂盒
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AI854034 ELISA试剂盒
MSK1 ELISA试剂盒
Msk1 ELISA试剂盒
MSPK1 ELISA试剂盒
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