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PLAU 抗体

(Plasminogen Activator, Urokinase (PLAU))
This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009].
PLAU 抗体  (N-Term) PLAU 抗体  (N-Term) PLAU 抗体 (N-Term) (ABIN1882148)

PLAU 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB04087 unconjugated

PLAU 抗体  (C-Term) PLAU 抗体  (C-Term) PLAU 抗体 (C-Term) (ABIN185470)

Verified PLAU 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

PLAU 抗体  (AA 60-90) PLAU 抗体  (AA 60-90) PLAU 抗体 (AA 60-90) (ABIN3032245)

PLAU 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

PLAU 抗体 by Grade

Find PLAU 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

PLAU 抗体 by 适用

Find PLAU 抗体 for a variety of species such as anti-Human PLAU, anti-Mouse PLAU, anti-Rat PLAU. The species listed below are among those available. Click on a link to go to the corresponding products.

PLAU 抗体 by 应用范围

Find PLAU 抗体 validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

PLAU 抗体 by 抗体来源

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PLAU 抗体 by 抗原表位

Find PLAU 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PLAU 抗体 by 克隆形成能力

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PLAU 抗体 by 克隆

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PLAU 抗体 by 标记

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PLAU 抗体 by Fragment

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Popular PLAU 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IHC (p), FACS
Validations
  • (8)
  • (4)
Cat. No. ABIN1882148
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (5)
Cat. No. ABIN185470
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, FACS
Validations
  • (6)
Cat. No. ABIN3032245
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, IF
Validations
  • (6)
Cat. No. ABIN3032244
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7431170
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN562262
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (2)
  • (2)
Cat. No. ABIN544968
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN2854759
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS, IF
Validations
  • (4)
Cat. No. ABIN392797
Quantity 400 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7431176
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7175129
Quantity 100 μg
Datasheet Datasheet
Reactivity Pig
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7431173
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN3023142
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN5531939
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN3028928
Quantity 0.4 mL
Datasheet Datasheet

Latest Publications for our PLAU 抗体

Dreymann, Sabrowski, Danso, Menger: "Aptamer-Based Sandwich Assay Formats for Detection and Discrimination of Human High- and Low-Molecular-Weight uPA for Cancer Prognosis and Diagnosis." in: Cancers, Vol. 14, Issue 21, (2022) (PubMed).

Liu, Zheng, Zhang, Wang, Yang, Bai, Dai: "Fucoxanthin Activates Apoptosis via Inhibition of PI3K/Akt/mTOR Pathway and Suppresses Invasion and Migration by Restriction of p38-MMP-2/9 Pathway in Human Glioblastoma Cells." in: Neurochemical research, Vol. 41, Issue 10, pp. 2728-2751, (2017) (PubMed).

Huang, Chang, Huang, Huang, Tang, Huang, Kuo, Chen, Cheng: "Urokinase-type plasminogen activator resulting from endometrial carcinogenesis enhances tumor invasion and correlates with poor outcome of endometrial carcinoma patients." in: Scientific reports, Vol. 5, pp. 10680, (2016) (PubMed).

Florova, Azghani, Karandashova, Schaefer, Koenig, Stewart-Evans, Declerck, Idell, Komissarov: "Targeting of plasminogen activator inhibitor 1 improves fibrinolytic therapy for tetracycline-induced pleural injury in rabbits." in: American journal of respiratory cell and molecular biology, Vol. 52, Issue 4, pp. 429-37, (2015) (PubMed).

Lee, Oh, Park, Na, Gil, Yang, Lee, Hong: "Urokinase, urokinase receptor, and plasminogen activator inhibitor-1 expression on podocytes in immunoglobulin A glomerulonephritis." in: The Korean journal of internal medicine, Vol. 29, Issue 2, pp. 176-82, (2014) (PubMed).

Komissarov, Florova, Azghani, Karandashova, Kurdowska, Idell: "Active ?-macroglobulin is a reservoir for urokinase after fibrinolytic therapy in rabbits with tetracycline-induced pleural injury and in human pleural fluids." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 305, Issue 10, pp. L682-92, (2013) (PubMed).

Botkjaer, Deryugina, Dupont, Gårdsvoll, Bekes, Thuesen, Chen, Chen, Ploug, Quigley, Andreasen: "Targeting tumor cell invasion and dissemination in vivo by an aptamer that inhibits urokinase-type plasminogen activator through a novel multifunctional mechanism." in: Molecular cancer research : MCR, Vol. 10, Issue 12, pp. 1532-43, (2012) (PubMed).

Coy, Jiménez-Movilla, García-Vázquez, Mondéjar, Grullón, Romar: "Oocytes use the plasminogen-plasmin system to remove supernumerary spermatozoa." in: Human reproduction (Oxford, England), Vol. 27, Issue 7, pp. 1985-93, (2012) (PubMed).

Kim, Minai-Tehrani, Kim, Shin, Hong, Kim, Lee, Chang, Yu, Bang, Cho, Yoon, Yu, Jiang, Cho: "Suppression of tumor growth in H-ras12V liver cancer mice by delivery of programmed cell death protein 4 using galactosylated poly(ethylene glycol)-chitosan-graft-spermine." in: Biomaterials, Vol. 33, Issue 6, pp. 1894-902, (2011) (PubMed).

Eefting, de Vries, Grimbergen, Karper, van Bockel, Quax et al.: "In vivo suppression of vein graft disease by nonviral, electroporation-mediated, gene transfer of tissue inhibitor of metalloproteinase-1 linked to the amino terminal fragment of urokinase ..." in: Journal of vascular surgery, Vol. 51, Issue 2, pp. 429-37, (2010) (PubMed).

Aliases for PLAU 抗体

plasminogen activator, urokinase (PLAU) 抗体
urokinase-type plasminogen activator (CpipJ_CPIJ002131) 抗体
urokinase-type plasminogen activator (CpipJ_CPIJ006543) 抗体
urokinase-type plasminogen activator (CpipJ_CPIJ013396) 抗体
urokinase-type plasminogen activator (CpipJ_CPIJ013623) 抗体
plasminogen activator, urokinase (Plau) 抗体
ATF 抗体
BDPLT5 抗体
PLAU 抗体
QPD 抗体
u-PA 抗体
UPA 抗体
uPA 抗体
UPAM 抗体
URK 抗体
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