Advanced Glycosylation End Product-Specific Receptor 蛋白 (AGER)产品概述

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Advanced Glycosylation End Product-Specific Receptor 蛋白 (AGER)
在www.antibodies-online.cn可供40 Advanced Glycosylation End Product-Specific Receptor (AGER) 蛋白的14不同的供货商。 再加上,我们可以发Advanced Glycosylation End Product-Specific Receptor 抗体 (308)Advanced Glycosylation End Product-Specific Receptor 试剂盒 (81)和数多这个蛋白质的别的产品。 总共446 Advanced Glycosylation End Product-Specific Receptor产品已列进来了。
别名:
AGER, RAGE
列出全部蛋白 基因 基因ID UniProt
AGER 177 Q15109
AGER 11596  
AGER 81722  

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引用最多的Advanced Glycosylation End Product-Specific Receptor 蛋白

  1. Mouse (Murine) AGER Protein expressed in Human Cells - ABIN2007883 : Sugaya, Fukagawa, Matsumoto, Mita, Takahashi, Ando, Inoko, Ikemura et al.: Three genes in the human MHC class III region near the junction with the class II: gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart ... in Genomics 1995 (PubMed)
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  2. Human AGER Protein expressed in Human Cells - ABIN2004449 : Neeper, Schmidt, Brett, Yan, Wang, Pan, Elliston, Stern, Shaw: Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins. in The Journal of biological chemistry 1992 (PubMed)
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  3. Human AGER Protein expressed in HEK-293 Cells - ABIN2180572 : Xue, Rai, Singer, Chabierski, Xie, Reverdatto, Burz, Schmidt, Hoffmann, Shekhtman: Advanced glycation end product recognition by the receptor for AGEs. in Structure (London, England : 1993) 2011 (PubMed)
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Human Advanced Glycosylation End Product-Specific Receptor (AGER) interaction partners

  1. AGER polymorphisms showed no statistically significant difference between patients with primary open-angle glaucoma and healthy controls.

  2. Our findings demonstrate how RAGE-PR3 interactions between human prostate cancer cells and the bone marrow microenvironment mediate bone metastasis during prostate cancer progression

  3. The severity of acute respiratory distress syndrome in preterm infants seemed to be associated with the plasma level of sRAGE and AQP5 (显示 AQP5 蛋白): the more severe the disease, the higher the plasma level of sRAGE and AQP5 (显示 AQP5 蛋白)

  4. Advanced glycation end products are capable of inducing VEGF (显示 VEGFA 蛋白) production and inflammatory responses via RAGE-NF-kappaB (显示 NFKB1 蛋白) pathway activation in synoviocytes.

  5. Atrial tissue expression of RAGE was significantly associated with atrial fibrosis in patients with mitral valve disease.

  6. RAGE drives tumor progression and metastasis through distinct tumor cell-intrinsic and -extrinsic mechanisms, and may represent a novel and therapeutically viable approach for treating metastatic cancers.

  7. these studies suggest that expression of RAGE in T cells of patients at risk for type 1 diabetes progressing to disease predates dysglycemia

  8. These studies confirm that intranasal insulin (显示 INS 蛋白) improves indexes of experimental DPN but indicates that females with DPN may differ in their underlying phenotype. RN mice had partial but incomplete protection from underlying DPN and lesser impacts from insulin (显示 INS 蛋白).

  9. findings show that RAGE binds RNA molecules in a sequence-independent manner and enhances cellular RNA uptake into endosomes; gain- and loss-of-function studies demonstrate that RAGE increases the sensitivity of all ssRNA-sensing TLRs (TLR7 (显示 TLR7 蛋白), TLR8 (显示 TLR8 蛋白), TLR13 (显示 Tlr13 蛋白)), suggesting RAGE is an integral part of the endosomal nucleic acid-sensing system

  10. HMGB1 (显示 HMGB1 蛋白) and sRAGE are not affected by combined antiretroviral therapy for HIV infection

Cow (Bovine) Advanced Glycosylation End Product-Specific Receptor (AGER) interaction partners

  1. Our results suggested that the increased RAGE expression in inflammatory circumstances and interaction with AGEs are risk factors in decreasing of aggrecan (显示 ACAN 蛋白) content in nucleus pulposus.

Mouse (Murine) Advanced Glycosylation End Product-Specific Receptor (AGER) interaction partners

  1. perturbation of Bone marrow mesenchymal stromal cells in diabetes mellitus could be partially explained by chronic RAGE signaling.

  2. RAGE mediates inflammation that contributes to lung damage, in cigarette smoke-induced lung pathology.

  3. Ager deletion enhances ischemic muscle inflammation, angiogenesis, and blood flow recovery in diabetic mice.

  4. HMGB1 (显示 HMGB1 蛋白) neither exerts influence on cardiac remodeling by binding to RAGE nor induces apoptosis of cardiomyocytes under physiological condition

  5. Our results indicate that lack of RAGE has no significant impact on septic arthritis. However, RAGE-/- mice had significantly higher BMD (显示 BEST1 蛋白) compared to WT mice, which coincided with lower IL-17A (显示 IL17A 蛋白) in RAGE-/- mice. In sepsis, RAGE deficiency impairs bacterial kidney clearance.

  6. SAA (显示 SAA1 蛋白) is a potential new uremic toxin involved in uremia-related atherosclerosis through interaction with RAGE.

  7. that selective RAGE regulation reflects a self-protective mechanism to maintain low levels of RAGE ligands

  8. Data show that receptor for advanced glycation end products (RAGE) impairs collateral growth in a diabetic setting and also in a non-diabetic setting, indicting the importance of RAGE and alternate RAGE ligands in the setting of collateral vessel growth.

  9. These findings demonstrate the role for RAGE-dependent IL-10 (显示 IL10 蛋白) suppression as a key modulator of mortality from Gram-negative sepsis.

  10. HMGB1 (显示 HMGB1 蛋白) promotes intraoral palatal wound healing through RAGE-dependent mechanisms.

蛋白简介Advanced Glycosylation End Product-Specific Receptor (AGER)

蛋白简介

The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847).

Alternative names and synonyms associated with Advanced Glycosylation End Product-Specific Receptor (AGER)

  • advanced glycosylation end product-specific receptor (AGER)
  • advanced glycosylation end product-specific receptor (Ager)
  • advanced glycosylation end product-specific receptor (LOC100343142)
  • AGER 蛋白
  • RAGE 蛋白

Protein level used designations for AGER

advanced glycosylation end product-specific receptor , RAGE isoform NtRAGE-delta , RAGE isoform sRAGE-delta , RAGE/AGER , advanced glycation end product receptor , advanced glycosylation end product-specific receptor variant 1 , advanced glycosylation end product-specific receptor variant 3 , advanced glycosylation end product-specific receptor variant 4 , advanced glycosylation end product-specific receptor variant 5 , advanced glycosylation end product-specific receptor variant 6 , advanced glycosylation end product-specific receptor variant 7 , advanced glycosylation end product-specific receptor variant 8 , receptor for advanced glycosylation end products , advanced glycation end-products receptor , advanced glycosylation end product-specific receptor variant 2

GENE ID SPECIES
462584 Pan troglodytes
177 Homo sapiens
403168 Canis lupus familiaris
396591 Sus scrofa
280986 Bos taurus
11596 Mus musculus
81722 Rattus norvegicus
100343142 Oryctolagus cuniculus
100726130 Cavia porcellus
101111586 Ovis aries
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