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AKR1C1 抗体

(Dihydrodiol Dehydrogenase (DDH))
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008].
AKR1C1 抗体 AKR1C1 抗体 AKR1C1 抗体 (ABIN2856139)

KO Validated DDH 适用: 人 WB, IHC, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated

AKR1C1 抗体  (AA 1-110) AKR1C1 抗体  (AA 1-110) AKR1C1 抗体 (AA 1-110) (ABIN560581)

DDH 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

AKR1C1 抗体  (AA 1-323) AKR1C1 抗体  (AA 1-323) AKR1C1 抗体 (AA 1-323) (ABIN514922)

DDH 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

AKR1C1 抗体 by Grade

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AKR1C1 抗体 by 适用

Find AKR1C1 抗体 for a variety of species such as anti-Human AKR1C1, anti-Rat AKR1C1, anti-Mouse AKR1C1. The species listed below are among those available. Click on a link to go to the corresponding products.

AKR1C1 抗体 by 应用范围

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AKR1C1 抗体 by 抗原表位

Find AKR1C1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

AKR1C1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal AKR1C1 抗体. Click on a link to go to the corresponding products.

AKR1C1 抗体 by 克隆

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AKR1C1 抗体 by 标记

Find AKR1C1 抗体 with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular AKR1C1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IHC (p), IF, ICC
Validations
  • (3)
  • (8)
Cat. No. ABIN2856139
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (2)
Cat. No. ABIN560581
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (3)
Cat. No. ABIN514922
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (2)
Cat. No. ABIN514921
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN1327000
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (2)
Cat. No. ABIN5774852
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7143686
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN7256524
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6136721
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Horse, Human, Pig, Rabbit, Rat
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN2788358
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN2788359
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN7299216
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
Cat. No. ABIN7188688
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7143689
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7143688
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our AKR1C1 抗体

Zhu, Hu, Zeng, Chang, Ge, Wang, Yan, Zhao, Cao, Ying, Gu, Zheng, He, Yang: "The SIRT2-mediated deacetylation of AKR1C1 is required for suppressing its pro-metastasis function in Non-Small Cell Lung Cancer." in: Theranostics, Vol. 10, Issue 5, pp. 2188-2200, (2020) (PubMed).

Zeng, Zhu, You, Dong, Yang, Zhu, He: "Liquiritin, as a Natural Inhibitor of AKR1C1, Could Interfere With the Progesterone Metabolism." in: Frontiers in physiology, Vol. 10, pp. 833, (2019) (PubMed).

Zhu, Chang, Yan, Hu, Zeng, Zhou, Yuan, Ying, Cao, He, Yang: "AKR1C1 Activates STAT3 to Promote the Metastasis of Non-Small Cell Lung Cancer." in: Theranostics, Vol. 8, Issue 3, pp. 676-692, (2018) (PubMed).

Chen, Solomides, Parekh, Simpkins, Simpkins: "Cisplatin resistance in human cervical, ovarian and lung cancer cells." in: Cancer chemotherapy and pharmacology, Vol. 75, Issue 6, pp. 1217-27, (2015) (PubMed).

Han, Bourboulia, Jensen-Taubman, Isaac, Wei, Stetler-Stevenson: "An endogenous inhibitor of angiogenesis inversely correlates with side population phenotype and function in human lung cancer cells." in: Oncogene, Vol. 33, Issue 9, pp. 1198-206, (2014) (PubMed).

Choi, Ryoo, Kang, Kwak: "The sensitivity of cancer cells to pheophorbide a-based photodynamic therapy is enhanced by Nrf2 silencing." in: PLoS ONE, Vol. 9, Issue 9, pp. e107158, (2014) (PubMed).

Ebert, Kisiela, Wsól, Maser: "Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 239-49, (2011) (PubMed).

Buytaert, Matroule, Durinck, Close, Kocanova, Vandenheede, de Witte, Piette, Agostinis: "Molecular effectors and modulators of hypericin-mediated cell death in bladder cancer cells." in: Oncogene, Vol. 27, Issue 13, pp. 1916-29, (2008) (PubMed).

McLoughlin, Irving, Brownlees, Brion, Leroy, Miller: "Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease." in: The European journal of neuroscience, Vol. 11, Issue 6, pp. 1988-94, (1999) (PubMed).

Borg, Straight, Kaech, de Taddéo-Borg, Kroon, Karnak, Turner, Kim, Margolis: "Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting." in: The Journal of biological chemistry, Vol. 273, Issue 48, pp. 31633-6, (1998) (PubMed).

Aliases for AKR1C1 抗体

aldo-keto reductase family 1 member C1 (AKR1C1) 抗体
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1) 抗体
2-ALPHA-HSD 抗体
20-ALPHA-HSD 抗体
C9 抗体
DD1 抗体
DD1/DD2 抗体
DDH 抗体
DDH1 抗体
H-37 抗体
HAKRC 抗体
HBAB 抗体
MBAB 抗体
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