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Human Thrombospondin 1 ELISA Kit for Sandwich ELISA - ABIN414489
Hoetzenecker, Assinger, Lichtenauer, Mildner, Schweiger, Starlinger, Jakab, Berényi, Pavo, Zimmermann, Gabriel, Plass, Gyöngyösi, Volf, Ankersmit et al.: Secretome of apoptotic peripheral blood cells (APOSEC) attenuates microvascular obstruction in a porcine closed chest reperfused acute myocardial infarction model: role of platelet aggregation and ... in Basic research in cardiology 2012
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Rat (Rattus) Thrombospondin 1 ELISA Kit for Sandwich ELISA - ABIN416163
Garcia-Diaz, Arellano, Milagro, Moreno-Aliaga, Portillo, Martinez, Campion: Glucose and insulin modify thrombospondin 1 expression and secretion in primary adipocytes from diet-induced obese rats. in Journal of physiology and biochemistry 2011
Mouse (Murine) Thrombospondin 1 ELISA Kit for Sandwich ELISA - ABIN415440
Kang, Lim, Lee, Yeo, Kang: Anthocyanin-rich purple corn extract inhibit diabetes-associated glomerular angiogenesis. in PLoS ONE 2013
Mouse (Murine) Thrombospondin 1 ELISA Kit for Sandwich ELISA - ABIN367912
Bourgeaux, Aufradet, Campion, De Souza, Horand, Bessaad, Chevrier, Canet-Soulas, Godfrin, Martin: Efficacy of homologous inositol hexaphosphate-loaded red blood cells in sickle transgenic mice. in British journal of haematology 2012
Genetic variants of THBS1 were significantly more frequent in patients affected by idiopathic/genetic generalized epilepsies than in non-epileptic controls.
In pulmonary hypertension TSP1-CD47 (显示 CD47 ELISA试剂盒) is upregulated, and contributes to pulmonary arterial vasculopathy and dysfunction.
High THBS1 expression is associated with primary effusion lymphoma.
Results show that the presence of OPN (显示 SPP1 ELISA试剂盒) and TSP-1 in the serum of patients with non-small cell lung cancer may reflect the aggressiveness of the tumor.
KLK4 (显示 KLK4 ELISA试剂盒) further liberated an N-terminal product, with purported angiogenic activity, from thrombospondin-1 (TSP1) and cleaved TSP1 in an osteoblast-derived matrix.
Data suggest pituitary cells secrete factor (TSP1) that binds to and inhibits action of BMP2 and BMP4; von Willebrand type C domain of TSP1 is likely responsible for this BMP2/4-binding activity. These studies were initially conducted using cultured cells from ovine pituitary gland and mouse cell line; interactions were confirmed using recombinant human proteins. (TSP1 = thrombospondin-1; BMP = bone morphogenetic protein)
the results obtained by combining bioinformatics and preclinical studies strongly suggest that targeting TSP-1/CD47 (显示 CD47 ELISA试剂盒) axis may represent a valuable therapeutic alternative for hampering melanoma spreading.
The levels of CD36 (显示 CD36 ELISA试剂盒), STAT3 (显示 STAT3 ELISA试剂盒) and TGFbetaR2 mRNA were significantly higher in the TSP1-high group.
Study discovered novel and independent associations of prediabetes and related traits with MASP1 (显示 MASP1 ELISA试剂盒), and some evidence for associations with THBS1, GPLD1 (显示 GPLD1 ELISA试剂盒) and ApoA-IV (显示 APOA4 ELISA试剂盒), suggesting a role for these proteins in the pathophysiology of type 2 diabetes.
TSP-1 deficiency promotes maladaptive remodelling of the ECM (显示 MMRN1 ELISA试剂盒) leading to accelerated abdominal aortic aneurysms progression.
In pulmonary hypertension TSP1 (显示 GZMA ELISA试剂盒)-CD47 (显示 CD47 ELISA试剂盒) is upregulated, and contributes to pulmonary arterial vasculopathy and dysfunction.
HIF-1alpha (显示 HIF1A ELISA试剂盒) induced angiogenesis by upregulating not only vascular endothelial growth factor but also miR (显示 MLXIP ELISA试剂盒)-21 via inhibiting a novel target gene TSP-1 (显示 GZMA ELISA试剂盒). Both of them may contribute to the protective effect of HIF-1alpha (显示 HIF1A ELISA试剂盒) on renal I/R injury.
the results obtained by combining bioinformatics and preclinical studies strongly suggest that targeting TSP-1 (显示 GZMA ELISA试剂盒)/CD47 (显示 CD47 ELISA试剂盒) axis may represent a valuable therapeutic alternative for hampering melanoma spreading.
TSP-1 (显示 GZMA ELISA试剂盒) deficiency promotes maladaptive remodelling of the ECM (显示 MMRN1 ELISA试剂盒) leading to accelerated abdominal aortic aneurysms progression.
TSP-1 (显示 GZMA ELISA试剂盒) suppressed insulin (显示 INS ELISA试剂盒) signaling in cultured muscle cells, which was accompanied by the activation of stress signaling such as JNK (显示 MAPK8 ELISA试剂盒), p38 (显示 CRK ELISA试剂盒), and IKK (显示 CHUK ELISA试剂盒).
Three transcription factors were overexpressed and eleven underexpressed in TSP1 (显示 GZMA ELISA试剂盒)(-/-) compared to WT LGs (显示 LGSN ELISA试剂盒).
THSD1 (显示 THSD1 ELISA试剂盒) is a new regulator of endothelial barrier function during vascular development and protects intraplaque microvessels against haemorrhaging in advanced atherosclerotic lesions
Data indicate that thrombospondin-1 may contribute to a destructive macrophage response in dysferlinopathy and pose the intriguing possibility that thrombospondin-1 levels may serve as a biomarker for disease progression.
demonstrate that HIF-2alpha (显示 EPAS1 ELISA试剂盒) is clearly implicated in the TSP1 (显示 GZMA ELISA试剂盒) pulmonary regulation and provide new insights on its contribution to pulmonary arterial hypertension-driven vascular remodelling and vasoconstriction
Thrombospondin-1 was differentially expressed according to tumor grade, but not affected by p53 (显示 TP53 ELISA试剂盒) expression or mutational status
Data suggest THBS1 expression predominates in luteal endothelial cells; THBS2 (显示 THBS2 ELISA试剂盒) expression predominates in luteinized granulosa cells. Luteinization down-regulates expression of THBS1/THBS2 (显示 THBS2 ELISA试剂盒), up-regulates expression of FGF2 (fibroblast growth factor 2 (显示 FGF2 ELISA试剂盒)).
Thrombospondin has a role in inducing RhoA (显示 RHOA ELISA试剂盒) inactivation through FAK (显示 PTK2 ELISA试剂盒)-dependent signaling to stimulate focal adhesion disassembly
Thrombospondin-1 and -2 were coordinately expressed in the extravascular compartment of the ovary during early follicle development. VEGF was inversely expressed, with expression increasing as follicles developed.
Preincubation of erythroid cells with thrombospondin 1 eliminated the inhibitory activity of insulin (显示 INS ELISA试剂盒)-like growth factor
The cell-specific regulation of TSP-1 suggests a potential mechanism for the aberrant angiogenesis in diabetics and TSP-1 involvement in development of various vascular diabetic complications
The novel finding that TSP-1-induced migration is dependent on the CD44 (显示 CD44 ELISA试剂盒) receptor links 2 pathways thought to be disparate (ie, TSP-1 and HyA (显示 KDM5D ELISA试剂盒)).
These current studies were undertaken to determine how TSP-1 functions to modulate the smooth muscle cell response to IGF-I (显示 IGF1 ELISA试剂盒) and the mechanisms by which hyperglycemia regulates TSP-1 protein.
Increased TSP-1 expression in non-heart-beating donors may indicate a compensatory response to the reported diminished TGF-beta1 (显示 TGFB1 ELISA试剂盒) expression.
ELL (显示 ELL ELISA试剂盒) (Eleven-Nineteen Lysine-rich Leukemia) acts as a transcription factor for direct thrombospondin-1 regulation
The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.
, thrombospondin 1