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FADD 抗体

(Fas (TNFRSF6)-Associated Via Death Domain (FADD))
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008].
FADD 抗体  (AA 12-206) FADD 抗体  (AA 12-206) FADD 抗体 (AA 12-206) (ABIN7439960)

FADD 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

FADD 抗体  (AA 1-208) FADD 抗体  (AA 1-208) FADD 抗体 (AA 1-208) (ABIN6140432)

FADD 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

FADD 抗体 FADD 抗体 FADD 抗体 (ABIN7267137)

FADD 适用: 小鼠 WB, IP, IF 宿主: 兔 Polyclonal unconjugated

FADD 抗体 by 适用

Find FADD 抗体 for a variety of species such as anti-Human FADD, anti-Mouse FADD, anti-Monkey FADD. The species listed below are among those available. Click on a link to go to the corresponding products.

FADD 抗体 by 应用范围

Find FADD 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

FADD 抗体 by 抗体来源

Find FADD 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

FADD 抗体 by 抗原表位

Find FADD 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

FADD 抗体 by 克隆形成能力

Find available monoclonal or polyclonal FADD 抗体. Click on a link to go to the corresponding products.

FADD 抗体 by 克隆

Find FADD 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

FADD 抗体 by 标记

Find FADD 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular FADD 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7439960
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (1)
  • (4)
Cat. No. ABIN6140432
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IP, IF
Validations
  • (4)
Cat. No. ABIN7267137
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (4)
Cat. No. ABIN7193411
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7439453
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7235044
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, PLA
Validations
  • (3)
Cat. No. ABIN522209
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN522210
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN7267135
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Pig, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
  • (1)
Cat. No. ABIN669471
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7138749
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7259174
Quantity 200 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN5577697
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6735927
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF, ICC
Validations
  • (3)
  • (1)
Cat. No. ABIN533782
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our FADD 抗体

Lindstrom, Sigurdardottir, Zapadka, Tang, Liu, Taylor, Smith, Lee, DeAngelis, Kern, Taylor: "Diabetes induces IL-17A-Act1-FADD-dependent retinal endothelial cell death and capillary degeneration." in: Journal of diabetes and its complications, Vol. 33, Issue 9, pp. 668-674, (2019) (PubMed).

Li, Mo, Lei, Li, Fu, Huang, Luo, Zhang: "Edaravone attenuates neuronal apoptosis in hypoxic-ischemic brain damage rat model via suppression of TRAIL signaling pathway." in: The international journal of biochemistry & cell biology, Vol. 99, pp. 169-177, (2018) (PubMed).

Cai, Lv, Kaldybayeva, Zhamilya, Wu, Wu: "15, 16-Dihydrotanshinone I Inhibits Hemangiomas through Inducing Pro-apoptotic and Anti-angiogenic Mechanisms in Vitro and in Vivo." in: Frontiers in pharmacology, Vol. 9, pp. 25, (2018) (PubMed).

Tian, Yao, Yang, Ren, Jiao, Zhang, Li, Zhang, Xia, Qin: "D4F alleviates macrophage-derived foam cell apoptosis by inhibiting the NF-κB-dependent Fas/FasL pathway." in: Scientific reports, Vol. 7, Issue 1, pp. 7333, (2017) (PubMed).

Soni, Adebiyi: "Early septic insult in neonatal pigs increases serum and urinary soluble Fas ligand and decreases kidney function without inducing significant renal apoptosis." in: Renal failure, pp. 1-12, (2016) (PubMed).

Papoff, Trivieri, Crielesi, Ruberti, Marsilio, Ruberti: "FADD-calmodulin interaction: a novel player in cell cycle regulation." in: Biochimica et biophysica acta, Vol. 1803, Issue 8, pp. 898-911, (2010) (PubMed).

Li, Jayarama, Ganesh, Mordi, Carr, Kanteti, Hay, Prabhakar: "Akt-phosphorylated mitogen-activated kinase-activating death domain protein (MADD) inhibits TRAIL-induced apoptosis by blocking Fas-associated death domain (FADD) association with death receptor 4." in: The Journal of biological chemistry, Vol. 285, Issue 29, pp. 22713-22, (2010) (PubMed).

Ko, Yang, Chung, Wen, Hsu, Miaw, Hsia: "Lack of Fas-pathway gene mutations in primary resected esophageal squamous cell carcinoma." in: Chang Gung medical journal, Vol. 33, Issue 2, pp. 145-51, (2010) (PubMed).

Hindryckx, De Vos, Jacques, Ferdinande, Peeters, Olievier, Bogaert, Brinkman, Vandenabeele, Elewaut, Laukens: "Hydroxylase inhibition abrogates TNF-alpha-induced intestinal epithelial damage by hypoxia-inducible factor-1-dependent repression of FADD." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 10, pp. 6306-16, (2010) (PubMed).

Silva, Blanton, Parrado, Melo, Morato, Reis, Dias, Castro, Vasconcelos, Goddard, Barreto, Reis, Teixeira: "Dengue hemorrhagic fever is associated with polymorphisms in JAK1." in: European journal of human genetics : EJHG, Vol. 18, Issue 11, pp. 1221-7, (2010) (PubMed).

Aliases for FADD 抗体

Fas associated via death domain (FADD) 抗体
Fas (TNFRSF6)-associated via death domain (Fadd) 抗体
Fas associated via death domain (Fadd) 抗体
Fas associated via death domain S homeolog (fadd.S) 抗体
Fas (tnfrsf6)-associated via death domain (fadd) 抗体
adaptor 抗体
fadd 抗体
MORT1 抗体
Mort1 抗体
mort1 抗体
Mort1/FADD 抗体
TNFRSF6 抗体
xfadd 抗体
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