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Cylindromatosis (Turban Tumor Syndrome) ELISA试剂盒 (CYLD)
在www.antibodies-online.cn可供9 Cylindromatosis (Turban Tumor Syndrome) (CYLD) ELISA试剂盒的5不同的供货商。 再加上,我们可以发CYLD 抗体 (79)CYLD 蛋白 (8)和数多这个蛋白质的别的产品。 总共99 CYLD产品已列进来了。
2010013M14Rik, 2900009M21Rik, BRSS, C130039D01Rik, CDMT, cyld, CYLD1, CYLDI, EAC, LRRGT00003, MFT, MFT1, mKIAA0849, Rp1, Rp1h, SBS, TEM, USPL2

适于 CYLD 相互作用对的更多 ELISA 试剂盒

Zebrafish Cylindromatosis (Turban Tumor Syndrome) (CYLD) interaction partners

  1. The crystal structures representing the catalytic states of zebrafish CYLD for Met1 (显示 DNMT1 ELISA试剂盒)- and Lys63-linked Ub chains and two distinct precatalytic states for Met1 (显示 DNMT1 ELISA试剂盒)-linked chains are presented.

Mouse (Murine) Cylindromatosis (Turban Tumor Syndrome) (CYLD) interaction partners

  1. TLR4 (显示 TLR4 ELISA试剂盒) activates CASPASE-8 (显示 CASP8 ELISA试剂盒) to cleave and remove the deubiquitinase cylindromatosis (CYLD) in a TRIF (显示 RNF138 ELISA试剂盒)- and RIPK1 (显示 RIPK1 ELISA试剂盒)-dependent manner to disable necroptosis in macrophages.

  2. CYLD contributes to the transdifferentiation of adventitial fibroblasts via deubiquitinating Nox4 (显示 NOX4 ELISA试剂盒) and may play a role in vascular remodeling.

  3. this study shows that by polarization of the T cell cytokine response, CYLD can favor the development of allergic airway disease

  4. Our findings underscore a critical tumor-suppressing role for functional intestinal epithelial CYLD in colitis-associated carcinogenesis

  5. Deubiquitinase CYLD negatively regulates MyD88 (显示 MYD88 ELISA试剂盒)-mediated signaling by directly interacting with MyD88 (显示 MYD88 ELISA试剂盒) and deubiquitinating nontypeable Haemophilus influenzae (NTHi)-induced K63-linked polyubiquitination of MyD88 (显示 MYD88 ELISA试剂盒) at lysine 231.

  6. CYLD interrupts the ERK (显示 EPHB2 ELISA试剂盒)- and p38 (显示 CRK ELISA试剂盒)-/AP-1 (显示 JUN ELISA试剂盒) and c-Myc (显示 MYC ELISA试剂盒) pathways to suppress Nrf2 (显示 NFE2L2 ELISA试剂盒)-operated antioxidative capacity, thereby enhancing oxidative stress in the heart.

  7. Our data demonstrate that inefficient negative selection in the thymus of CYLD(ex7/8) mice result from a defect in mTEC maturation.

  8. The deubiquitinating enzyme CYLD controls apical docking of basal bodies in ciliated epithelial cells.

  9. Data show that the in utero death of NF-NF (显示 NFASC ELISA试剂盒)-kappaB (显示 NFKB1 ELISA试剂盒) essential modulator (NEMO (显示 IKBKG ELISA试剂盒)) and cylindromatosis protein double mutant mice is mediated by TNF (显示 TNF ELISA试剂盒) receptor 1 (TNFR1 (显示 TNFRSF1A ELISA试剂盒)) signaling and can be rescued by TNFR1 (显示 TNFRSF1A ELISA试剂盒) deficiency.

  10. CYLD is a central regulator of apoptotic cell death in murine hepatocytes by controlling NF-kappaB (显示 NFKB1 ELISA试剂盒) dependent anti-apoptotic signaling.

Human Cylindromatosis (Turban Tumor Syndrome) (CYLD) interaction partners

  1. The data reveal SPATA2 as a high-affinity binding partner of CYLD and HOIP (显示 RNF31 ELISA试剂盒), and a regulatory component of linear ubiquitin chain assembly complex-mediated NF-kappaB (显示 NFKB1 ELISA试剂盒) signaling.

  2. The current investigations identified a subset of HPV-positive HNSCCs with mutations in the genes TRAF3 (显示 TRAF3 ELISA试剂盒) (tumor necrosis factor (显示 TNF ELISA试剂盒) receptor-associated factor 3) and CYLD (cylindromatosis lysine 63 deubiquitinase). Defects in TRAF3 (显示 TRAF3 ELISA试剂盒) and CYLD correlated with the activation of transcriptional factor nuclear factor kappaB, episomal HPV status of tumors, and improved patient survival.

  3. The predicted PUB domain in the N-terminus of SPATA2 interacts with the USP domain of CYLD and SPATA2 is required for recruitment of CYLD to the TNF-alpha receptor-associated signaling complexes.

  4. STAT3 (显示 STAT3 ELISA试剂盒) and miR (显示 MLXIP ELISA试剂盒)-181b control each other's expression in a positive feedback loop that regulates SFCs via CYLD pathway.

  5. CYLD Promotes TNF-alpha (显示 TNF ELISA试剂盒)-Induced Cell Necrosis Mediated by RIP-1 in Human Lung Cancer Cells

  6. Low CYLD expression is associated with hepatocellular carcinoma.

  7. miR20a directly repressed the expression of CYLD, leading to activation of the NFkappaB (显示 NFKB1 ELISA试剂盒) pathway and the downstream targets, livin (显示 BIRC7 ELISA试剂盒) and survivin (显示 BIRC5 ELISA试剂盒), which potentially induced GC chemoresistance.

  8. Data show that cylindromatosis (CYLD) overexpression and livin (显示 BIRC7 ELISA试剂盒) knockdown might improve gemcitabine chemosensitivity by decreasing autophagy and increasing apoptosis in bladder cancer (BCa (显示 BLNK ELISA试剂盒)) cells.

  9. aberrantly expressed miR (显示 MLXIP ELISA试剂盒)-130b may regulate cell apoptosis and proliferation of human gastric cancer cells via CYLD, which appears to be a promising therapeutic target for gastric cancer

  10. These results demonstrate the involvement of histone deacetylases in the down regulation of Cyld expression in hepatocellular carcinoma cells.

CYLD 抗原简介

Antigen Summary

This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with CYLD

  • cylindromatosis (turban tumor syndrome) (CYLD) Elisa Kit
  • cylindromatosis (turban tumor syndrome), a (cylda) Elisa Kit
  • ubiquitin carboxyl-terminal hydrolase CYLD (LOC100362727) Elisa Kit
  • cylindromatosis (turban tumor syndrome) (Cyld) Elisa Kit
  • 2010013M14Rik Elisa Kit
  • 2900009M21Rik Elisa Kit
  • BRSS Elisa Kit
  • C130039D01Rik Elisa Kit
  • CDMT Elisa Kit
  • cyld Elisa Kit
  • CYLD1 Elisa Kit
  • CYLDI Elisa Kit
  • EAC Elisa Kit
  • LRRGT00003 Elisa Kit
  • MFT Elisa Kit
  • MFT1 Elisa Kit
  • mKIAA0849 Elisa Kit
  • Rp1 Elisa Kit
  • Rp1h Elisa Kit
  • SBS Elisa Kit
  • TEM Elisa Kit
  • USPL2 Elisa Kit

Protein level used designations for CYLD

cylindromatosis (turban tumor syndrome) , probable ubiquitin carboxyl-terminal hydrolase CYLD-like , ubiquitin carboxyl-terminal hydrolase CYLD , deubiquitinating enzyme CYLD , ubiquitin thioesterase CYLD , ubiquitin thiolesterase CYLD , ubiquitin-specific-processing protease CYLD , probable ubiquitin carboxyl-terminal hydrolase CYLD , retinitis pigmentosa 1 homolog , ubiquitin specific peptidase like 2

100050308 Equus caballus
556823 Danio rerio
100467467 Ailuropoda melanoleuca
100547998 Meleagris gallopavo
100362727 Rattus norvegicus
74256 Mus musculus
312937 Rattus norvegicus
1540 Homo sapiens
611649 Canis lupus familiaris
536421 Bos taurus
415725 Gallus gallus
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