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FLIP 抗体

(CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011].
FLIP 抗体  (AA 100-251) FLIP 抗体  (AA 100-251) FLIP 抗体 (AA 100-251) (ABIN1724850)

CFLAR 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7A3D12 unconjugated

FLIP 抗体  (AA 178-277) FLIP 抗体  (AA 178-277) FLIP 抗体 (AA 178-277) (ABIN563829)

CFLAR 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 2F12 unconjugated

FLIP 抗体  (AA 1-250) FLIP 抗体  (AA 1-250) FLIP 抗体 (AA 1-250) (ABIN7146901)

CFLAR 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

FLIP 抗体 by 适用

Find FLIP 抗体 for a variety of species such as anti-Human FLIP, anti-Mouse FLIP, anti-Rat FLIP. The species listed below are among those available. Click on a link to go to the corresponding products.

FLIP 抗体 by 应用范围

Find FLIP 抗体 validated for a specific application such as WB, IF (cc), ELISA, IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

FLIP 抗体 by 抗体来源

Find FLIP 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

FLIP 抗体 by 抗原表位

Find FLIP 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

FLIP 抗体 by 克隆形成能力

Find available monoclonal or polyclonal FLIP 抗体. Click on a link to go to the corresponding products.

FLIP 抗体 by 克隆

Find FLIP 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

FLIP 抗体 by 标记

Find FLIP 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular FLIP 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, FACS
Validations
  • (2)
  • (6)
Cat. No. ABIN1724850
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF
Validations
  • (7)
Cat. No. ABIN563829
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7146901
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IP, IF
Validations
  • (4)
Cat. No. ABIN522287
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, ICC, IHC (p)
Validations
  • (4)
Cat. No. ABIN461877
Quantity 0.05 mg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (4)
Cat. No. ABIN3016247
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IHC (p), IF (p), IHC (fro)
Validations
  • (3)
Cat. No. ABIN737946
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IHC (p), FACS, IF (p), IHC (fro)
Validations
  • (3)
Cat. No. ABIN725255
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Horse, Human, Mouse, Rat
Application WB
Validations
  • (4)
Cat. No. ABIN2792098
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC, IP
Validations
  • (2)
Cat. No. ABIN7443605
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN948737
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, PLA
Validations
  • (2)
Cat. No. ABIN522286
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN522284
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, ICC, IF
Validations
  • (2)
  • (1)
Cat. No. ABIN533803
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ICC
Validations
  • (2)
Cat. No. ABIN541790
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our FLIP 抗体

Van Opdenbosch, Van Gorp, Verdonckt, Saavedra, de Vasconcelos, Gonçalves, Vande Walle, Demon, Matusiak, Van Hauwermeiren, DHont, Hochepied, Krautwald, Kanneganti, Lamkanfi: "Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4." in: Cell reports, Vol. 21, Issue 12, pp. 3427-3444, (2018) (PubMed).

Hartwig, Montinaro, von Karstedt, Sevko, Surinova, Chakravarthy, Taraborrelli, Draber, Lafont, Arce Vargas, El-Bahrawy, Quezada, Walczak: "The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2." in: Molecular cell, Vol. 65, Issue 4, pp. 730-742.e5, (2017) (PubMed).

Garimella, Gehlhaus, Dine, Pitt, Grandin, Chakka, Nau, Caplen, Lipkowitz: "Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening." in: Breast cancer research : BCR, Vol. 16, Issue 2, pp. R41, (2014) (PubMed).

Dannappel, Vlantis, Kumari, Polykratis, Kim, Wachsmuth, Eftychi, Lin, Corona, Hermance, Zelic, Kirsch, Basic, Bleich, Kelliher, Pasparakis: "RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis." in: Nature, Vol. 513, Issue 7516, pp. 90-4, (2014) (PubMed).

Bucur, Pennarun, Stancu, Nadler, Muraru, Bertomeu, Khosravi-Far: "Poor antibody validation is a challenge in biomedical research: a case study for detection of c-FLIP." in: Apoptosis : an international journal on programmed cell death, Vol. 18, Issue 10, pp. 1154-62, (2013) (PubMed).

Toporkiewicz, Grzybek, Meissner, Michalczyk, Dubielecka, Korycka, Seweryn, Sikorski: "Release of an ~55kDa fragment containing the actin-binding domain of ?-spectrin by caspase-8 during FND-induced apoptosis depends on the presence of protein 4.1." in: Archives of biochemistry and biophysics, Vol. 535, Issue 2, pp. 205-13, (2013) (PubMed).

Rao-Bindal, Rao, Yu, Kleinerman: "Expression of c-FLIP in pulmonary metastases in osteosarcoma patients and human xenografts." in: Pediatric blood & cancer, Vol. 60, Issue 4, pp. 575-9, (2013) (PubMed).

Bedolla, Gong, Prihoda, Yeh, Thompson, Ghosh, Kumar: "Predictive value of Sp1/Sp3/FLIP signature for prostate cancer recurrence." in: PLoS ONE, Vol. 7, Issue 9, pp. e44917, (2012) (PubMed).

Li, Ren, Yue, Chen, Khuri, Sun: "The novel Akt inhibitor API-1 induces c-FLIP degradation and synergizes with TRAIL to augment apoptosis independent of Akt inhibition." in: Cancer prevention research (Philadelphia, Pa.), Vol. 5, Issue 4, pp. 612-20, (2012) (PubMed).

Noh, Lee, Sung, Song, Kim, Woo, Kwon, Lee: "CHOP down-regulates cFLIP(L) expression by promoting ubiquitin/proteasome-mediated cFLIP(L) degradation." in: Journal of cellular biochemistry, Vol. 113, Issue 12, pp. 3692-700, (2012) (PubMed).

Aliases for FLIP 抗体

CASP8 and FADD-like apoptosis regulator a (cflara) 抗体
CASP8 and FADD like apoptosis regulator (CFLAR) 抗体
CASP8 and FADD like apoptosis regulator (cflar) 抗体
CASP8 and FADD like apoptosis regulator S homeolog (cflar.S) 抗体
CASP8 and FADD-like apoptosis regulator (Cflar) 抗体
2310024N18Rik 抗体
A430105C05Rik 抗体
c-FLIP 抗体
c-Flip 抗体
c-FLIPL 抗体
c-FLIPR 抗体
c-FLIPS 抗体
CASH 抗体
Cash 抗体
CASP8AP1 抗体
Casper 抗体
cflar 抗体
CFLAR 抗体
CLARP 抗体
Clarp1 抗体
ENSMUSG00000072980 抗体
FLAME 抗体
FLAME-1 抗体
FLAME1 抗体
FLIP 抗体
Flip 抗体
Gm9845 抗体
I-FLICE 抗体
MRIT 抗体
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