anti-小鼠 Caspase 8 抗体 for Enzyme Immunoassay

Recommended Caspase 8 Antibody (supplied by: Log in to see )

抗原
Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) 抗体
  • casp8-A
  • xCaspase-8
  • casp8
  • CASP8
  • CASP-8
  • FLICE
  • MACH
  • Mch5
  • ALPS2B
  • CAP4
  • Casp-8
  • MCH5
  • caspase-8
  • zgc:92075
  • caspase 8, apoptosis-related cysteine peptidase
  • death related ced-3/Nedd2-like protein
  • caspase-8
  • caspase 8
  • casp8
  • Dredd
  • CASP8
  • AaeL_AAEL014148
  • LOC100222284
  • Casp8
  • LOC100348477
抗原表位
C-Term
42
19
18
16
15
12
10
10
9
8
7
6
6
6
6
5
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用
人, 小鼠, 大鼠
360
120
95
25
21
20
3
2
1
宿主

278
115
10
2
克隆类型
多克隆
标记
This Caspase 8 antibody is un-conjugated
18
13
8
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
应用范围
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
360
109
92
79
51
36
36
27
14
13
9
7
6
5
2
2
2
1
1
1
1
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产品编号 ABIN5554665
$ 375.38
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5554666 EIA WB Rabbit IgG Log in to see Polyclonal
1 ABIN187452 EIA IHC (fro) WB Rat IgG1 Log in to see 1G12
1 ABIN1105678 EIA FACS IHC (p) WB Mouse IgG1 Log in to see 1H11

General

抗原 Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) 抗体
抗原表位 C-Term
(42), (19), (18), (16), (15), (12), (10), (10), (9), (8), (7), (6), (6), (6), (6), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用 人, 小鼠, 大鼠
(360), (120), (95), (25), (21), (20), (3), (2), (1)
宿主
(278), (115), (10), (2)
克隆类型
多克隆
标记 This Caspase 8 antibody is un-conjugated
(18), (13), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(360), (109), (92), (79), (51), (36), (36), (27), (14), (13), (9), (7), (6), (5), (2), (2), (2), (1), (1), (1), (1)
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Caspase 8抗体详情

Caspase 8目标详情 使用细节 贮存及处理 图像
特异性 Caspase-8 antibody was raised against a 16 amino acid peptide from near the carboxy-terminus of human Caspase-8 isoform A.
纯化方法 Affinity chromatography purified via peptide column
免疫原 Virus Casp-8 / FLICE / MACH / Mch5 (C-Terminus) Peptide
亚型 IgG

Caspase 8目标详情

Caspase 8抗体详情 使用细节 贮存及处理 图像 回页首
抗原
别名 Caspase-8 (CASP8 Antibody 摘要)
背景 Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens (reviewed in 1 and 2). The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death (reviewed in 3). Caspase-8 is an initiator caspase that was identified as a member of the Fas/APO-1 death-inducing signaling complex (4). The adaptor molecule FADD couples procaspase-8 to the Fas receptor death domain, subsequent oligomerization promotes procaspase-8 autoactivation (reviewed in 5). FLIP, a catalytically inactive caspase-8-like molecule inhibits these interactions and thus can inhibit apoptosis (6).Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, CASP-8, CASP8, FADD-homologous ICE/CED-3-like protease, FADD-like ICE, ICE-like apoptotic protease 5, MCH5, MORT1-associated CED-3 homolog
基因ID 841
NCBI登录号 NP_001219
UniProt Q14790
研究领域 Apoptosis/Necrosis
途径 Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades

使用细节

Caspase 8抗体详情 Caspase 8目标详情 贮存及处理 图像 回页首
应用备注 ELISA. Western Blot: Caspase-8 antibody can be used for the detection of caspase-8 at 0.5 μg/mL. Depending on cell lines or tissues used, either full-length or other cleavage products maybe observed. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用

贮存及处理

Caspase 8抗体详情 Caspase 8目标详情 使用细节 图像 回页首
缓冲液 PBS containing 0.02 % sodium azide.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C
储存方法 Store the antibody undiluted at 2-8 °C.