anti-Caspase 3 (CASP3) 抗体产品概述

Full name:
anti-Caspase 3, Apoptosis-Related Cysteine Peptidase 抗体 (CASP3)
在www.antibodies-online.cn可供634 Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) 抗体的42不同的供货商。 再加上,我们可以发Caspase 3 试剂盒 (93)Caspase 3 蛋白 (44)和数多这个蛋白质的别的产品。 总共826 Caspase 3产品已列进来了。
别名:
A830040C14Rik, AC-3, Apopain, Cas3, Casp 3, Casp3, caspase-3, caspase 3, CC3, CG7788, CG14902, CPP32, CPP32B, crice, Decay, Dmel\\CG7788, Dmel\\CG14902, drice, Drosophila executioner caspase related to Apopain/Yama, ice, Lice, mldy, SCA-1, xcpp32, Yama

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引用最多的anti-Caspase 3 抗体

  1. Human Polyclonal Caspase 3 Primary Antibody for IHC, WB - ABIN222873 : Fernando, Kelly, Balazsi, Slack, Megeney: Caspase 3 activity is required for skeletal muscle differentiation. in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
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  2. Human Polyclonal Caspase 3 Primary Antibody for WB - ABIN222951 : Atkin, Farg, Turner, Tomas, Lysaght, Nunan, Rembach, Nagley, Beart, Cheema, Horne: Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1. in The Journal of biological chemistry 2006 (PubMed)
    Show all 8 references for 222951

  3. Human Polyclonal Caspase 3 Primary Antibody for FACS, IHC (p) - ABIN655271 : Würstle, Laussmann, Rehm: The caspase-8 dimerization/dissociation balance is a highly potent regulator of caspase-8, -3, -6 signaling. in The Journal of biological chemistry 2010 (PubMed)
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  4. Human Polyclonal Caspase 3 Primary Antibody for EIA, IHC (p) - ABIN359724 : Wright, Farquhar, Aletrari, Ladds, Hodgkin: Identification of caspase 3 motifs and critical aspartate residues in human phospholipase D1b and phospholipase D2a. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 3 references for 359724

  5. Human Polyclonal Caspase 3 Primary Antibody for DB, IHC (p) - ABIN650861 : Mei, Yong, Liu, Shi, Meinkoth, Dreyfuss, Yang: tRNA binds to cytochrome c and inhibits caspase activation. in Molecular cell 2010 (PubMed)
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  6. Human Polyclonal Caspase 3 Primary Antibody for WB - ABIN783310 : Gervais, Xu, Robertson, Vaillancourt, Zhu, Huang, LeBlanc, Smith, Rigby, Shearman, Clarke, Zheng, Van Der Ploeg, Ruffolo, Thornberry, Xanthoudakis, Zamboni, Roy, Nicholson: Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation. in Cell 1999 (PubMed)
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  7. Human Monoclonal Caspase 3 Primary Antibody for IHC (p), WB - ABIN400729 : Cartault, Munier, Benko, Desguerre, Hanein, Boddaert, Bandiera, Vellayoudom, Krejbich-Trotot, Bintner, Hoarau, Girard, Génin, de Lonlay, Fourmaintraux, Naville, Rodriguez, Feingold, Renouil, Munnich, Westhof, Fähling, Lyonnet, Henrion-Caude: Mutation in a primate-conserved retrotransposon reveals a noncoding RNA as a mediator of infantile encephalopathy. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)

  8. Cow (Bovine) Polyclonal Caspase 3 Primary Antibody for IHC, WB - ABIN2774596 : Selvakumar, Smith-Windsor, Bonham, Sharma: N-myristoyltransferase 2 expression in human colon cancer: cross-talk between the calpain and caspase system. in FEBS letters 2006 (PubMed)

  9. Human Polyclonal Caspase 3 Primary Antibody for ELISA, WB - ABIN1536103 : Tewari, Quan, ORourke, Desnoyers, Zeng, Beidler, Poirier, Salvesen, Dixit: Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. in Cell 1995 (PubMed)

更多抗Caspase 3的相互作用对抗体

Fruit Fly (Drosophila melanogaster) Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) interaction partners

  1. Genetic characterization of two gain-of-function alleles of the effector caspase DrICE in Drosophila.

  2. drICE plays an important role in activating corpse clearance in dying cells, and that an additional function of effector caspases is required for the activation of corpse clearance as well as that for carrying out cell death.

  3. Both autophagy and caspase activity are induced by 20-hydroxyecdysone during the larval-prepupal transition.

  4. The cleaved DIAP1 (显示 DIAPH1 抗体) binds drICE, inhibits its protease activity, and also targets drICE for ubiquitylation.

  5. Drosophila corazonin-producing interneuron programmed cell death utilizes dronc, strica, dcp-1 (显示 ACE 抗体), and ice

  6. Data suggest that the cleaved-Caspase-3 antibody recognizes multiple proteins including DCP-1 (显示 ACE 抗体) and likely DRICE, but also at least one additional unknown protein, all of which require DRONC for epitope exposure.

  7. The caspase effector DRICE is activated during apoptosis in both mid- and late oogenesis; however, active DRICE was found more ubiquitously and at a higher level during germline cell death in midoogenesis.

  8. examination of inhibition by DIAP1 (显示 DIAPH1 抗体)

  9. Ecdysone-mediated up-regulation of the effector caspase DRICE is required for hormone-dependent apoptosis in Drosophila cells.

  10. A double-mutant analysis between drICE and death caspase-1 (dcp-1), another effector caspase, reveals that some cells (type I) strictly require drICE for apoptosis, whereas other cells (type II) require either drICE or dcp-1 (显示 ACE 抗体).

Mouse (Murine) Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) interaction partners

  1. report that mutating the caspase-3 consensus site in the EAAT2 (显示 SLC1A2 抗体) sequence with an aspartate to asparagine mutation

  2. These studies suggest a link between Bik (显示 BIK 抗体)-mediated caspase activation and cleavage of viral proteins.

  3. melatonin could inhibit TLR4 (显示 TLR4 抗体) expression in hypoxic microglia followed by suppression of caspase3 activation leading to decrease in production of proinflammatory mediators

  4. A significant emergence of GFP-expressing PCs and interneurons in symptomatic, but not non-symptomatic, SCA1 (显示 ATXN1 抗体) mice 2 weeks after the MSC (显示 MSC 抗体) injection.

  5. Conversely, treatment with LY294002 (a selective inhibitor of Akt1 (显示 AKT1 抗体)) reversed the effects of quercetin. In conclusion, these findings highlight the important role of quercetin in protecting against cognitive deficits and inhibiting neuronal apoptosis via the Akt (显示 AKT1 抗体) signaling pathway. We believe that quercetin might prove to be a useful therapeutic component in treating cerebral I/R diseases in the near future.

  6. cognitive decline was significantly correlated with increased levels of caspase activity and tau truncated by caspase-3

  7. this study shows that Le Carbone, a charcoal supplement, attenuates experimental colitis through caspase 3 dependent apoptotic pathways

  8. Cepharanthine treatment reduced mitochondrial membrane potential and upregulated the level of cleaved caspases, including caspase-9 (显示 CASP9 抗体) and caspase-3/7, in a dose-dependent fashion.

  9. Our results showed that Sca-1 (显示 Ly6a 抗体)(+) MSCs inhibit the commitment of marginal zone B lymphocytes. The inhibition was exerted through lowered Caspase-3 expression. Furthermore, we found marginal zone B lymphocytes in spleen of Caspase-3 knockout mice decreased and Caspase-3 knockout Sca-1 (显示 Ly6a 抗体)(+) MSCs accounted for the MZB lymphocytes decrease.

  10. caspase-3 is essential for a subset of social behaviors, but despite similar hyper-locomotion in both sexes, only male Casp3(-/-) mice exhibited social interaction deficits, which is interesting given the male bias of autism

Human Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) interaction partners

  1. Caspase 3 activation in dying glioma cells unfavorably supported post-irradiation angiogenesis.

  2. Bcl-xL (显示 BCL2L1 抗体) is an exosomal caspase-3 substrate and that this processing is required for the uptake of exosomes by recipient cells.

  3. CASP3 is a direct target of specific Epstein-Barr virus BART (显示 BSND 抗体) miRNAs.

  4. Data suggest that EV71 infection in enterocytes does not inhibit phosphorylation of STAT1 (显示 STAT1 抗体)/2 induced by IFN-beta (显示 IFNB1 抗体), but p-STAT1 (显示 STAT1 抗体)/2 transport into the nucleus is significantly blocked; EV71 infection in enterocytes down-regulates expression of KPNA1 (显示 KPNA1 抗体) and induces degradation of cellular KPNA1 (显示 KPNA1 抗体) via caspase-3. [EV17 = Enterovirus 71]

  5. our results identified that mammalian sterile 20-like kinase 1 (显示 STK4 抗体) is a novel downstream target of pyruvate kinase M2, and knockdown of pyruvate kinase M2 contributes apoptosis via promoting nuclear translocation of mammalian sterile 20-like kinase 1 (显示 STK4 抗体) by enhancing Caspase-3-dependent cleavage.

  6. These studies suggest a link between Bik (显示 BIK 抗体)-mediated caspase activation and cleavage of viral proteins.

  7. High levels of FADD (显示 FADD 抗体) and caspase-8 (显示 CASP8 抗体), but not caspase-3, were associated with increased incidence of coronary events in subjects from the general population.

  8. Interestingly, EspC-induced apoptosis was triggered through a dual mechanism involving both independent and dependent functions of its EspC serine protease (显示 F2 抗体) motif, the direct cleavage of procaspase-3 being dependent on this motif.

  9. LRRC8A (显示 LRRC8A 抗体) is an essential regulator of cisplatin induced p53 (显示 TP53 抗体) protein activity and its downstream signaling involving increased expression of p21Waf1/Cip1 and MDM2 (显示 MDM2 抗体), as well as activation of caspase-9 (显示 CASP9 抗体) and -3 in tumor cell lines.

  10. Our results provide evidence that inhibition of the denitrosylation of S-nitrosylated procaspase-3 mediated by the redox protein Trx2 is a part of the microglial pro-tumoral activation pathway initiated by glioma cancer cells.

Cow (Bovine) Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) interaction partners

  1. Over-expression of STC-1 (显示 STC1 抗体) up-regulated Bcl-2 (显示 BCL2 抗体) protein expression and slightly down-regulated caspase-3 production in the damaged cells. Findings from this study suggest that STC-1 (显示 STC1 抗体) plays a protective role in intestinal cells through an antioxidant mechanism.

  2. Data suggest that Escherichia coli infections (here, administration of LPS (显示 IRF6 抗体)) provokes luteolysis in diestrus, non-lactating cows and up-regulation of expression of caspase 3 in corpus luteum but has no effect on luteinization in the following cycle.

  3. Data suggest that activation of caspase-3 is likely involved in both spontaneous and induced apoptosis in bovine pre-implantation embryos.

  4. mRNA expression of Bax (显示 BAX 抗体), Bcl-2 (显示 BCL2 抗体), caspase-3 and-7 cannot be used as a reliable apoptosis detection method.

  5. the capacity for blastocysts to undergo further development is related to degree of group II caspase activity

  6. Treatment of mammary epithelial cells with serotonin 1B and serotonin 2A receptor antagonists increased caspase-3 activity.

Pig (Porcine) Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) interaction partners

  1. This study demonstrated that LAMPs from M. hyopneumoniae can induce apoptosis in St. Jude porcine lung epithelial cell line through the activation of caspase 3, caspase 8 (显示 CASP8 抗体), cyt c (显示 CYCS 抗体), Bax (显示 BAX 抗体), and p38 MAPK (显示 MAPK14 抗体).

  2. Caspase-3 (CC3) was shown to be more abundant in early-cleaving and more developmentally competent embryos compared to late-cleaving and less developmentally competent embryos.

  3. Results suggest that zearalenone induces apoptosis and necrosis of porcine granulosa cells in a dose-dependent manner via a caspase-3- and caspase-9 (显示 CASP9 抗体)-dependent mitochondrial pathway.

  4. FiO2 used for resuscitation affects matrix metalloproteinases MMP-9 (显示 MMP9 抗体) and MMP-2 (显示 MMP2 抗体), caspase-3 and BDNF (显示 BDNF 抗体)

  5. both caspase-3-dependent and -independent pathways of programmed cell death increased upon Salmonella typhimurium infection.

  6. clonidine administration prior to hypoxia prevents the hypoxia-induced increase in the activity of caspase-3 in the cerebral cortex.

  7. Suppressive effect of FSH (显示 BRD2 抗体) and LH on p53 (显示 TP53 抗体) expression and caspase-3 activity with parallel increase in bcl-2 (显示 BCL2 抗体) expression and increased P production was observed

  8. Ischemic preconditioning exerts a powerful protective effect against hepatic ischemia-reperfusion injury in the early phase of reperfusion, which may be mediated by preservation of mitochondrial structure and inhibition of caspase-3 activity.

Rabbit Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) interaction partners

  1. excessive apoptosis does occur in acetabular cartilage with developmental dislocations of the hip, and is positively correlated with high caspase-3 expression as well as low Bcl-2 (显示 BCL2 抗体) expression.

  2. This study revealed that the 810-nm low-level laser can improve cartilage structure, prevent articular cartilage degradation and significantly decrease the expression of caspase-3 in this surgery-induced osteoarthritis model.

  3. Morphine hypoxic preconditioning can protect rabbits against acute kidney hypoxic/reoxygenation injury by decreasing expression of caspase-3.

  4. Isoflurane delayed preconditioning can inhibit the apoptosis of myocardium by up-regulating the expression of Bcl-2 (显示 BCL2 抗体) and down-regulating the activation of caspase-3.

  5. High frequency oscillatory ventilation combined with exogenous pulmonary surfactant can decrease the concentration of caspase-3 and p73 (显示 ARHGAP24 抗体) rabbit with acute respiratory failure.

Xenopus laevis Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) interaction partners

  1. Hyperosmotic Shock Engages Two Positive Feedback Loops through Caspase-3-dependent Proteolysis of JNK1 (显示 MAPK8 抗体)-2 and Bid (显示 BID 抗体).

  2. in the developing diencephalon, Caspase3 acts downstream of Barhl2 (显示 BARHL2 抗体) in limiting neuroepithelial cell proliferation by inhibiting beta-catenin (显示 CTNNB1 抗体) activation.

  3. PP2A:B56{epsilon}, a substrate of caspase-3, regulates p53 (显示 TP53 抗体)-dependent and p53 (显示 TP53 抗体)-independent apoptosis during development.

Caspase 3 (CASP3) 抗原简介

Antigen Summary

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

Alternative names and synonyms associated with Caspase 3 (CASP3)

  • caspase 3, apoptosis-related cysteine peptidase (CASP3) 抗体
  • death executioner caspase related to Apopain/Yama (decay) 抗体
  • CG7788 gene product from transcript CG7788-RA (Ice) 抗体
  • caspase 3 (Casp3) 抗体
  • caspase 3, apoptosis-related cysteine peptidase (Casp3) 抗体
  • caspase 3, apoptosis-related cysteine peptidase (casp3) 抗体
  • A830040C14Rik 抗体
  • AC-3 抗体
  • Apopain 抗体
  • Cas3 抗体
  • Casp 3 抗体
  • Casp3 抗体
  • caspase-3 抗体
  • caspase 3 抗体
  • CC3 抗体
  • CG7788 抗体
  • CG14902 抗体
  • CPP32 抗体
  • CPP32B 抗体
  • crice 抗体
  • Decay 抗体
  • Dmel\\CG7788 抗体
  • Dmel\\CG14902 抗体
  • drice 抗体
  • Drosophila executioner caspase related to Apopain/Yama 抗体
  • ice 抗体
  • Lice 抗体
  • mldy 抗体
  • SCA-1 抗体
  • xcpp32 抗体
  • Yama 抗体

Protein level used designations for CASP3

Caspase-3-like protein , caspase-3 , CG14902-PA , Caspase-3 , caspase 3 , caspase-3 protein , cleaved caspase 3 , decay-PA , CG7788-PA , Ice-PA , drice , interleukin-1beta-converting enzyme , CASP-3 , CPP-32 , SCA-1 , SREBP cleavage activity 1 , caspase 3, apoptosis related cysteine protease , cysteine protease CPP32 , protein Yama , CPP32beta , Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease) , Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease) , IRP , apopain , yama protein , PARP cleavage protease , caspase 3, apoptosis-related cysteine protease , procaspase3

GENE ID SPECIES
100034083 Equus caballus
42008 Drosophila melanogaster
43514 Drosophila melanogaster
12367 Mus musculus
25402 Rattus norvegicus
836 Homo sapiens
408016 Bos taurus
403567 Canis lupus familiaris
397244 Sus scrofa
443031 Ovis aries
100008840 Oryctolagus cuniculus
395476 Gallus gallus
100718309 Cavia porcellus
493932 Felis catus
397720 Xenopus laevis
461669 Pan troglodytes
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