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BIM 抗体

(BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jul 2008].
BIM 抗体  (AA 2-120) BIM 抗体  (AA 2-120) BIM 抗体 (AA 2-120) (ABIN7430234)

BCL2L11 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

BIM 抗体  (pSer87) BIM 抗体  (pSer87) BIM 抗体 (pSer87) (ABIN682873)

BCL2L11 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

BIM 抗体  (AA 1-198) BIM 抗体  (AA 1-198) BIM 抗体 (AA 1-198) (ABIN7145302)

BCL2L11 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

BIM 抗体 by Grade

Find BIM 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

BIM 抗体 by 适用

Find BIM 抗体 for a variety of species such as anti-Human BIM, anti-Mouse BIM, anti-Rat BIM. The species listed below are among those available. Click on a link to go to the corresponding products.

BIM 抗体 by 应用范围

Find BIM 抗体 validated for a specific application such as WB, IHC, ELISA, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

BIM 抗体 by 抗体来源

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BIM 抗体 by 抗原表位

Find BIM 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

BIM 抗体 by 克隆形成能力

Find available monoclonal or polyclonal BIM 抗体. Click on a link to go to the corresponding products.

BIM 抗体 by 克隆

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BIM 抗体 by 标记

Find BIM 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular BIM 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (8)
Cat. No. ABIN7430234
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (2)
  • (2)
Cat. No. ABIN682873
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, IF
Validations
  • (3)
Cat. No. ABIN7145302
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (1)
  • (2)
Cat. No. ABIN361750
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (4)
Cat. No. ABIN652493
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, EIA
Validations
  • (4)
Cat. No. ABIN453531
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC (p), FACS
Validations
  • (2)
Cat. No. ABIN687277
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7138680
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN2485937
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN2485942
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN2485941
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN2485936
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN2485928
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN2485930
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN2485927
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our BIM 抗体

Peperzak, Slinger, Ter Burg, Eldering: "Functional disparities among BCL-2 members in tonsillar and leukemic B-cell subsets assessed by BH3-mimetic profiling." in: Cell death and differentiation, Vol. 24, Issue 1, pp. 111-119, (2018) (PubMed).

Jiao, Li, Zhang, Liu, Chi: "Role of Sirtuin3 in high glucose-induced apoptosis in renal tubular epithelial cells." in: Biochemical and biophysical research communications, Vol. 480, Issue 3, pp. 387-393, (2017) (PubMed).

Luan, Jin, Jiang, Tay, Lai, Liu, Liu, Guo, Li, Yan, Tseng, Zhang: "RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy." in: Autophagy, Vol. 11, Issue 7, pp. 975-94, (2015) (PubMed).

Wang, Lv, Cheng, Du, Chen, Li, Zhang: "Apoptosis induced by Ginkgo biloba (EGb761) in melanoma cells is Mcl-1-dependent." in: PLoS ONE, Vol. 10, Issue 4, pp. e0124812, (2015) (PubMed).

Lee, Maeng, Kang, Choi, Oh, Ju, Yune: "Valproic acid protects motor neuron death by inhibiting oxidative stress and endoplasmic reticulum stress-mediated cytochrome C release after spinal cord injury." in: Journal of neurotrauma, Vol. 31, Issue 6, pp. 582-94, (2014) (PubMed).

Gogada, Yadav, Liu, Tang, Zhang, Schneider, Seshadri, Sun, Aldaz, Tang, Chandra: "Bim, a proapoptotic protein, up-regulated via transcription factor E2F1-dependent mechanism, functions as a prosurvival molecule in cancer." in: The Journal of biological chemistry, Vol. 288, Issue 1, pp. 368-81, (2013) (PubMed).

Wroblewski, Jiang, Croft, Farrelly, Zhang, Hersey: "OBATOCLAX and ABT-737 induce ER stress responses in human melanoma cells that limit induction of apoptosis." in: PLoS ONE, Vol. 8, Issue 12, pp. e84073, (2013) (PubMed).

Cash, Gruber, Hartman, Henske, Simon: "Loss of the Birt-Hogg-Dubé tumor suppressor results in apoptotic resistance due to aberrant TGFβ-mediated transcription." in: Oncogene, Vol. 30, Issue 22, pp. 2534-46, (2011) (PubMed).

Loh, Liou, Jiau, Cheng, Shih, Chen: "Hepatic effects among workers exposed to ethylene glycol monoethyl ether acetate." in: Industrial health, Vol. 46, Issue 5, pp. 463-9, (2008) (PubMed).

Del Gaizo Moore, Schlis, Sallan, Armstrong, Letai: "BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia." in: Blood, Vol. 111, Issue 4, pp. 2300-9, (2008) (PubMed).

Aliases for BIM 抗体

BCL2-like 11 (bcl2l11) 抗体
BCL2 like 11 (BCL2L11) 抗体
BCL2-like 11 (apoptosis facilitator) (Bcl2l11) 抗体
BCL2 like 11 (Bcl2l11) 抗体
1500006F24Rik 抗体
BAM 抗体
bim 抗体
BIM 抗体
Bim 抗体
BIMEL 抗体
BimL 抗体
BOD 抗体
Bod 抗体
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