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PAK2 抗体 (P21-Activated Kinase 2)

Details for Product anti-PAK2 Antibody No. ABIN969338, 供应商: Log in to see
抗原
  • pak2
  • cb422
  • kinase
  • zgc:91798
  • wu:fb71h01
  • si:dz198m22.1
  • pak65
  • pakgamma
  • PAK65
  • PAKgamma
  • 5330420P17Rik
  • A130002K10Rik
  • AI836325
  • D16Ertd269e
  • PAK-2
  • mKIAA4182
  • gamma-PAK
  • PAKI
  • Pak3
  • p21 (CDKN1A)-activated kinase 2a
  • p21 protein (Cdc42/Rac)-activated kinase 2
  • pak2a
  • pak2
  • PAK2
  • Pak2
适用
人, 猴
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宿主
小鼠
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克隆类型 (克隆位点)
单克隆 ()
标记
This PAK2 antibody is un-conjugated
4
4
4
4
4
4
应用范围
Immunocytochemistry (ICC), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
166
100
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Supplier
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Supplier Product No.
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免疫原 Purified recombinant fragment of PAK2 expressed in E. Coli.
克隆位点 3B5
亚型 IgG1
纯化方法 Ascites
别名 PAK2 (PAK2 Antibody 摘要)
背景 PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.
分子量 61 kDa
基因ID 5062
HGNC 5062
研究领域 Cancer, Apoptosis/Necrosis, Tyrosine Kinases, Kinases/Phosphatases
途径 MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
应用备注 ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
限制 仅限研究用
状态 Liquid
缓冲液 Ascitic fluid containing 0.03 % sodium azide.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C,-20 °C
储存方法 4°C, -20°C for long term storage
厂商提供的图像
Immunocytochemistry (ICC) image for anti-P21-Activated Kinase 2 (PAK2) antibody (ABIN969338) Figure 1: Confocal immunofluorescence analysis of Hela cells using PAK2 mouse mAb (gr...
Immunohistochemistry (IHC) image for anti-P21-Activated Kinase 2 (PAK2) antibody (ABIN969338) Figure 2: Immunohistochemical analysis of paraffin-embedded human lung cancer (left) ...
Western Blotting (WB) image for anti-P21-Activated Kinase 2 (PAK2) antibody (ABIN969338) Figure 3: Western blot analysis using PAK2 mouse mAb against Hela (1), Jurkat (2), A5...
有引用在: Machuy, Campa, Thieck, Rudel: "c-Abl-binding protein interacts with p21-activated kinase 2 (PAK-2) to regulate PDGF-induced membrane ruffles." in: Journal of molecular biology, Vol. 370, Issue 4, pp. 620-32, 2007 (PubMed).

Chu, Wu, Liao, Pardo, Zhao, Li, Mendenhall, Pali, Shen, Yu, Taylor, Aversa, Molineaux, Payan, Masuda: "A novel role for p21-activated protein kinase 2 in T cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 12, pp. 7324-34, 2004 (PubMed).

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